1. Creating polymer templates and their use in the in-situ synthesis of biodegradable composite networks.
- Author
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Patil, Nitin, Kelsey, Jarred, Fischer, Jordan, Grady, Brian, and White, Jeffery L.
- Subjects
- *
CHEMICAL templates , *POLYMER analysis , *BIODEGRADABLE plastics , *POLYMERIC composites , *POLYETHYLENE oxide , *POLYCAPROLACTONE - Abstract
Abstract: A biodegradable polyethyleneoxide–polycaprolactone–polyethyleneoxide (PEO–PCL–PEO or PECE) triblock polymer was synthesized as a structure-directing agent for high-surface area silica formation. Systematic end-group functionalization of the triblock polymer, prior to its use as a structure-directing agent for high-surface area silica growth, imparts an additional reactive function that is exploited to grow a continuous organic phase within and around the silica particles. Hence, the biodegradable triblock also acts as a macromer whose dual function leads to in-situ generation of intimately mixed biopolymer/nanoporous–silica composite networks. This composite can be both biodegradable and biocompatible, and the modulus is comparable to other non-biodegradable materials. [Copyright &y& Elsevier]
- Published
- 2014
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