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1. Low frequency magnetic fields enhance antitumor immune response against mouse H22 hepatocellular carcinoma.

Author

Yunzhong Nie, Yueqiu Chen, Yongbin Mou, Leihua Weng, Zhenjun Xu, Youwei Du, Wenmei Wang, Yayi Hou, and Tingting Wang

Subjects
Medicine, Science
Abstract

OBJECTIVE: Many studies have shown that magnetic fields (MF) inhibit tumor growth and influence the function of immune system. However, the effect of MF on mechanism of immunological function in tumor-bearing mice is still unclear. METHODS: In this study, tumor-bearing mice were prepared by subcutaneously inoculating Balb/c mice with hepatocarcinoma cell line H22. The mice were then exposed to a low frequency MF (0.4 T, 7.5 Hz) for 30 days. Survival rate, tumor growth and the innate and adaptive immune parameters were measured. RESULTS: MF treatment could prolong survival time (n = 28, p

Published
2013
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2. Low frequency magnetic fields enhance antitumor immune response against mouse H22 hepatocellular carcinoma

Author

Wenmei Wang, Youwei Du, Yayi Hou, Yongbin Mou, Leihua Weng, Yueqiu Chen, Yunzhong Nie, Zhenjun Xu, and Tingting Wang

Subjects
Chemokine, Carcinoma, Hepatocellular, Cell Survival, T-Lymphocytes, lcsh:Medicine, Spleen, Adaptive Immunity, Granulocyte, Real-Time Polymerase Chain Reaction, Flow cytometry, Mice, Immune system, Immunity, Cell Line, Tumor, medicine, Animals, lcsh:Science, Mice, Inbred BALB C, Multidisciplinary, medicine.diagnostic_test, biology, Liver Neoplasms, lcsh:R, Flow Cytometry, Immunohistochemistry, Immunity, Innate, Magnetic Fields, medicine.anatomical_structure, Cell culture, Immunology, biology.protein, Cancer research, Cytokines, Female, lcsh:Q, CD8, Research Article
Abstract

Objective Many studies have shown that magnetic fields (MF) inhibit tumor growth and influence the function of immune system. However, the effect of MF on mechanism of immunological function in tumor-bearing mice is still unclear. Methods In this study, tumor-bearing mice were prepared by subcutaneously inoculating Balb/c mice with hepatocarcinoma cell line H22. The mice were then exposed to a low frequency MF (0.4 T, 7.5 Hz) for 30 days. Survival rate, tumor growth and the innate and adaptive immune parameters were measured. Results MF treatment could prolong survival time (n = 28, p

Published
2013

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