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4 results on '"Thompson, Claudia"'

1. Genomic Analyses and Transcriptional Profiles of the Glycoside Hydrolase Family 18 Genes of the Entomopathogenic Fungus Metarhizium anisopliae

Author

Junges, Ângela, primary, Boldo, Juliano Tomazzoni, additional, Souza, Bárbara Kunzler, additional, Guedes, Rafael Lucas Muniz, additional, Sbaraini, Nicolau, additional, Kmetzsch, Lívia, additional, Thompson, Claudia Elizabeth, additional, Staats, Charley Christian, additional, de Almeida, Luis Gonzaga Paula, additional, de Vasconcelos, Ana Tereza Ribeiro, additional, Vainstein, Marilene Henning, additional, and Schrank, Augusto, additional

Published
2014
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2. Predicting the Proteins of Angomonas deanei, Strigomonas culicis and Their Respective Endosymbionts Reveals New Aspects of the Trypanosomatidae Family

Author

Motta, Maria Cristina Machado, primary, Martins, Allan Cezar de Azevedo, additional, de Souza, Silvana Sant’Anna, additional, Catta-Preta, Carolina Moura Costa, additional, Silva, Rosane, additional, Klein, Cecilia Coimbra, additional, de Almeida, Luiz Gonzaga Paula, additional, de Lima Cunha, Oberdan, additional, Ciapina, Luciane Prioli, additional, Brocchi, Marcelo, additional, Colabardini, Ana Cristina, additional, de Araujo Lima, Bruna, additional, Machado, Carlos Renato, additional, de Almeida Soares, Célia Maria, additional, Probst, Christian Macagnan, additional, de Menezes, Claudia Beatriz Afonso, additional, Thompson, Claudia Elizabeth, additional, Bartholomeu, Daniella Castanheira, additional, Gradia, Daniela Fiori, additional, Pavoni, Daniela Parada, additional, Grisard, Edmundo C., additional, Fantinatti-Garboggini, Fabiana, additional, Marchini, Fabricio Klerynton, additional, Rodrigues-Luiz, Gabriela Flávia, additional, Wagner, Glauber, additional, Goldman, Gustavo Henrique, additional, Fietto, Juliana Lopes Rangel, additional, Elias, Maria Carolina, additional, Goldman, Maria Helena S., additional, Sagot, Marie-France, additional, Pereira, Maristela, additional, Stoco, Patrícia H., additional, de Mendonça-Neto, Rondon Pessoa, additional, Teixeira, Santuza Maria Ribeiro, additional, Maciel, Talles Eduardo Ferreira, additional, de Oliveira Mendes, Tiago Antônio, additional, Ürményi, Turán P., additional, de Souza, Wanderley, additional, Schenkman, Sergio, additional, and de Vasconcelos, Ana Tereza Ribeiro, additional

Published
2013
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3. Metagenomic Analysis of the Microbiota from the Crop of an Invasive Snail Reveals a Rich Reservoir of Novel Genes

Author

Cardoso, Alexander M., primary, Cavalcante, Janaína J. V., additional, Cantão, Maurício E., additional, Thompson, Claudia E., additional, Flatschart, Roberto B., additional, Glogauer, Arnaldo, additional, Scapin, Sandra M. N., additional, Sade, Youssef B., additional, Beltrão, Paulo J. M. S. I., additional, Gerber, Alexandra L., additional, Martins, Orlando B., additional, Garcia, Eloi S., additional, de Souza, Wanderley, additional, and Vasconcelos, Ana Tereza R., additional

Published
2012
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4. Predicting the Proteins of Angomonas deanei, Strigomonas culicis and Their Respective Endosymbionts Reveals New Aspects of the Trypanosomatidae Family.

Author

Motta, Maria Cristina Machado, Martins, Allan Cezar de Azevedo, de Souza, Silvana Sant’Anna, Catta-Preta, Carolina Moura Costa, Silva, Rosane, Klein, Cecilia Coimbra, de Almeida, Luiz Gonzaga Paula, de Lima Cunha, Oberdan, Ciapina, Luciane Prioli, Brocchi, Marcelo, Colabardini, Ana Cristina, de Araujo Lima, Bruna, Machado, Carlos Renato, de Almeida Soares, Célia Maria, Probst, Christian Macagnan, de Menezes, Claudia Beatriz Afonso, Thompson, Claudia Elizabeth, Bartholomeu, Daniella Castanheira, Gradia, Daniela Fiori, and Pavoni, Daniela Parada

Subjects
TRYPANOSOMATIDAE, ENDOSYMBIOSIS, CELLULAR evolution, PROTOZOAN proteins, PHYLOGENY, NUCLEOTIDE sequence, COMPARATIVE studies
Abstract

Endosymbiont-bearing trypanosomatids have been considered excellent models for the study of cell evolution because the host protozoan co-evolves with an intracellular bacterium in a mutualistic relationship. Such protozoa inhabit a single invertebrate host during their entire life cycle and exhibit special characteristics that group them in a particular phylogenetic cluster of the Trypanosomatidae family, thus classified as monoxenics. In an effort to better understand such symbiotic association, we used DNA pyrosequencing and a reference-guided assembly to generate reads that predicted 16,960 and 12,162 open reading frames (ORFs) in two symbiont-bearing trypanosomatids, Angomonas deanei (previously named as Crithidia deanei) and Strigomonas culicis (first known as Blastocrithidia culicis), respectively. Identification of each ORF was based primarily on TriTrypDB using tblastn, and each ORF was confirmed by employing getorf from EMBOSS and Newbler 2.6 when necessary. The monoxenic organisms revealed conserved housekeeping functions when compared to other trypanosomatids, especially compared with Leishmania major. However, major differences were found in ORFs corresponding to the cytoskeleton, the kinetoplast, and the paraflagellar structure. The monoxenic organisms also contain a large number of genes for cytosolic calpain-like and surface gp63 metalloproteases and a reduced number of compartmentalized cysteine proteases in comparison to other TriTryp organisms, reflecting adaptations to the presence of the symbiont. The assembled bacterial endosymbiont sequences exhibit a high A+T content with a total of 787 and 769 ORFs for the Angomonas deanei and Strigomonas culicis endosymbionts, respectively, and indicate that these organisms hold a common ancestor related to the Alcaligenaceae family. Importantly, both symbionts contain enzymes that complement essential host cell biosynthetic pathways, such as those for amino acid, lipid and purine/pyrimidine metabolism. These findings increase our understanding of the intricate symbiotic relationship between the bacterium and the trypanosomatid host and provide clues to better understand eukaryotic cell evolution. [ABSTRACT FROM AUTHOR]

Published
2013
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