Search

Your search keyword '"Tanaka, Masashi"' showing total 15 results
Start Over Author "Tanaka, Masashi" Journal plos one
15 results on '"Tanaka, Masashi"'

1. Polymorphic SERPINA3 prolongs oligomeric state of amyloid beta

Author

Akbor, Maruf Mohammad, primary, Kurosawa, Nobuyuki, additional, Nakayama, Hiroki, additional, Nakatani, Ayumi, additional, Tomobe, Koji, additional, Chiba, Yoichi, additional, Ueno, Masaki, additional, Tanaka, Masashi, additional, Nomura, Yasuyuki, additional, and Isobe, Masaharu, additional

Published
2021
Full Text
View/download PDF

4. Gender-linked impact of epicardial adipose tissue volume in patients who underwent coronary artery bypass graft surgery or non-coronary valve surgery

Author

Maimaituxun, Gulinu, primary, Shimabukuro, Michio, additional, Salim, Hotimah Masdan, additional, Tabata, Minoru, additional, Yuji, Daisuke, additional, Morimoto, Yoshihisa, additional, Akasaka, Takeshi, additional, Matsuura, Tomomi, additional, Yagi, Shusuke, additional, Fukuda, Daiju, additional, Yamada, Hirotsugu, additional, Soeki, Takeshi, additional, Sugimoto, Takaki, additional, Tanaka, Masashi, additional, Takanashi, Shuichiro, additional, and Sata, Masataka, additional

Published
2017
Full Text
View/download PDF

6. Osteoinduction on Acid and Heat Treated Porous Ti Metal Samples in Canine Muscle

Author

Kawai, Toshiyuki, primary, Takemoto, Mitsuru, additional, Fujibayashi, Shunsuke, additional, Akiyama, Haruhiko, additional, Tanaka, Masashi, additional, Yamaguchi, Seiji, additional, Pattanayak, Deepak K., additional, Doi, Kenji, additional, Matsushita, Tomiharu, additional, Nakamura, Takashi, additional, Kokubo, Tadashi, additional, and Matsuda, Shuichi, additional

Published
2014
Full Text
View/download PDF

10. SIRT1 Regulates Thyroid-Stimulating Hormone Release by Enhancing PIP5Kγ Activity through Deacetylation of Specific Lysine Residues in Mammals

Author

Akieda-Asai, Sayaka, primary, Zaima, Nobuhiro, additional, Ikegami, Koji, additional, Kahyo, Tomoaki, additional, Yao, Ikuko, additional, Hatanaka, Takahiro, additional, Iemura, Shun-ichiro, additional, Sugiyama, Rika, additional, Yokozeki, Takeaki, additional, Eishi, Yoshinobu, additional, Koike, Morio, additional, Ikeda, Kyoji, additional, Chiba, Takuya, additional, Yamaza, Haruyoshi, additional, Shimokawa, Isao, additional, Song, Si-Young, additional, Matsuno, Akira, additional, Mizutani, Akiko, additional, Sawabe, Motoji, additional, Chao, Moses V., additional, Tanaka, Masashi, additional, Kanaho, Yasunori, additional, Natsume, Tohru, additional, Sugimura, Haruhiko, additional, Date, Yukari, additional, McBurney, Michael W., additional, Guarente, Leonard, additional, and Setou, Mitsutoshi, additional

Published
2010
Full Text
View/download PDF

13. Mitochondrial DNA Haplogroup D4a Is a Marker for Extreme Longevity in Japan

Author

Bilal, Erhan, primary, Rabadan, Raul, additional, Alexe, Gabriela, additional, Fuku, Noriyuki, additional, Ueno, Hitomi, additional, Nishigaki, Yutaka, additional, Fujita, Yasunori, additional, Ito, Masafumi, additional, Arai, Yasumichi, additional, Hirose, Nobuyoshi, additional, Ruckenstein, Andrei, additional, Bhanot, Gyan, additional, and Tanaka, Masashi, additional

Published
2008
Full Text
View/download PDF

14. Distilling Artificial Recombinants from Large Sets of Complete mtDNA Genomes.

Author

Qing-Peng Kong, Salas, Antonio, Chang Sun, Fuku, Noriyuki, Tanaka, Masashi, Li Zhong, Cheng-Ye Wang, Yong-Gang Yao, and Bandelt, Hans-Jürgen

Subjects
RECOMBINANT DNA, STANDARD deviations, BIOMARKERS, NUCLEOTIDE sequence, MITOCHONDRIAL DNA, PHYLOGENY, GENOMES
Abstract

Background: Large-scale genome sequencing poses enormous problems to the logistics of laboratory work and data handling. When numerous fragments of different genomes are PCR amplified and sequenced in a laboratory, there is a high immanent risk of sample confusion. For genetic markers, such as mitochondrial DNA (mtDNA), which are free of natural recombination, single instances of sample mix-up involving different branches of the mtDNA phylogeny would give rise to reticulate patterns and should therefore be detectable. Methodology/Principal Findings: We have developed a strategy for comparing new complete mtDNA genomes, one by one, to a current skeleton of the worldwide mtDNA phylogeny. The mutations distinguishing the reference sequence from a putative recombinant sequence can then be allocated to two or more different branches of this phylogenetic skeleton. Thus, one would search for two (or three) near-matches in the total mtDNA database that together best explain the variation seen in the recombinants. The evolutionary pathway from the mtDNA tree connecting this pair together with the recombinant then generate a grid-like median network, from which one can read off the exchanged segments. Conclusions: We have applied this procedure to a large collection of complete human mtDNA sequences, where several recombinants could be distilled by our method. All these recombinant sequences were subsequently corrected by de novo experiments - fully concordant with the predictions from our data-analytical approach. [ABSTRACT FROM AUTHOR]

Published
2008
Full Text
View/download PDF

15. DdrA, DdrD, and PprA: Components of UV and Mitomycin C Resistance in Deinococcus radiodurans R1.

Author

Selvam, Kathiresan, Duncan, Jana R., Tanaka, Masashi, and Battista, John R.

Subjects
MITOMYCIN C, DEINOCOCCUS radiodurans, ULTRAVIOLET radiation, MUTANT proteins, DNA damage, GENETIC polymorphisms, SENSITIVITY analysis, PREVENTION
Abstract

Mutants created by deleting the ddrA, ddrB, ddrC, ddrD, and pprA loci of Deinococcus radiodurans R1alone and in all possible combinations of pairs revealed that the encoded gene products contribute to this species’ resistance to UV light and/or mitomycin C. Deleting pprA from an otherwise wild type cell sensitizes the resulting strain to UV irradiation, reducing viability by as much as eight fold relative to R1. If this deletion is introduced into a ΔddrA or ΔddrD background, the resulting strains become profoundly sensitive to the lethal effects of UV light. At a fluence of 1000 Jm-2, the ΔddrA ΔpprA and ΔddrD ΔpprA strains are 100- and 1000-fold more sensitive to UV relative to the strain that has only lost pprA. Deletion of ddrA results in a 100 fold increase in strain sensitivity to mitomycin C, but in backgrounds that combine a deletion of ddrA with deletions of either ddrC or ddrD, mitomycin resistance is restored to wild type levels. Inactivation of ddrB also increases D. radiodurans sensitivity to mitomycin, but unlike the ddrA mutant deleting ddrC or ddrD from a ΔddrB background further increases that sensitivity. Despite the effect that loss of these gene products has on DNA damage resistance, none appear to directly affect either excision repair or homologous recombination suggesting that they participate in novel processes that facilitate tolerance to UV light and interstrand crosslinks in this species. [ABSTRACT FROM AUTHOR]

Published
2013
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results