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2 results on '"Su-Shan Tsai"'

1. The Association between Obstructive Sleep Apnea and Metabolic Markers and Lipid Profiles.

Author

Wei-Te Wu, Su-Shan Tsai, Tung-Sheng Shih, Ming-Hsiu Lin, Tzu-Chieh Chou, Hua Ting, Trong-Neng Wu, and Saou-Hsing Liou

Subjects
Medicine, Science
Abstract

The purpose of this study was to investigate the association between apnea-hypopnea index (AHI) and metabolic markers and whether the elevated risk of Metabolic Syndrome (MetS) is related to Obstructive Sleep Apnea (OSA).This cross-sectional study recruited 246 male bus drivers from one transportation company in Taiwan. Each participant was evaluated by a polysomnography (PSG) test and by blood lipids examination. Severity of OSA was categorized according to the apnea-hypopnea index (AHI).The results showed that a 73.3% prevalence of MetS in OSA (AHI > 15) and a 80.0% prevalence of MetS in severe OSA (AHI > 30) were found. After adjusting for confounding variables, an increased level of Body-Mass Index (BMI) and two non-MetS cardiovascular risk factors, total cholesterol/HDL-C ratio and TG/HDL-C ratio was significantly associated with AHI in subjects with severe OSA. MetS was about three times to be present in subjects with severe OSA, even adjusted for BMI.The findings showed a high prevalence of MetS in OSA among professional drivers, especially in the severe group category. BMI was the major contributing factor to OSA. However, the present study did not find a sensitive clinical marker of a detrimental metabolic profile in OSA patients.

Published
2015
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2. The Association between Obstructive Sleep Apnea and Metabolic Markers and Lipid Profiles

Author

Saou-Hsing Liou, Wei-Te Wu, Tzu-Chieh Chou, Su-Shan Tsai, Hua Ting, Ming-Hsiu Lin, Trong-Neng Wu, and Tung-Sheng Shih

Subjects
Adult, Blood Glucose, Male, medicine.medical_specialty, Polysomnography, lcsh:Medicine, Blood lipids, Poison control, Blood Pressure, Severity of Illness Index, Oxygen Consumption, stomatognathic system, Risk Factors, Internal medicine, Prevalence, Medicine, Humans, Obesity, lcsh:Science, Metabolic Syndrome, Sleep Apnea, Obstructive, Multidisciplinary, medicine.diagnostic_test, business.industry, lcsh:R, nutritional and metabolic diseases, Sleep apnea, Middle Aged, medicine.disease, Lipid Metabolism, Lipids, nervous system diseases, respiratory tract diseases, Obstructive sleep apnea, Physical therapy, lcsh:Q, Female, Metabolic syndrome, business, Body mass index, Biomarkers, Research Article
Abstract

PURPOSE: The purpose of this study was to investigate the association between apnea-hypopnea index (AHI) and metabolic markers and whether the elevated risk of Metabolic Syndrome (MetS) is related to Obstructive Sleep Apnea (OSA). METHODS: This cross-sectional study recruited 246 male bus drivers from one transportation company in Taiwan. Each participant was evaluated by a polysomnography (PSG) test and by blood lipids examination. Severity of OSA was categorized according to the apnea-hypopnea index (AHI). RESULTS: The results showed that a 73.3% prevalence of MetS in OSA (AHI > 15) and a 80.0% prevalence of MetS in severe OSA (AHI > 30) were found. After adjusting for confounding variables, an increased level of Body-Mass Index (BMI) and two non-MetS cardiovascular risk factors, total cholesterol/HDL-C ratio and TG/HDL-C ratio was significantly associated with AHI in subjects with severe OSA. MetS was about three times to be present in subjects with severe OSA, even adjusted for BMI. CONCLUSIONS: The findings showed a high prevalence of MetS in OSA among professional drivers, especially in the severe group category. BMI was the major contributing factor to OSA. However, the present study did not find a sensitive clinical marker of a detrimental metabolic profile in OSA patients. Language: en

Published
2014

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