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2 results on '"Siqun Zheng"'

1. Genome-wide association scan for variants associated with early-onset prostate cancer.

Author

Ethan M Lange, Anna M Johnson, Yunfei Wang, Kimberly A Zuhlke, Yurong Lu, Jessica V Ribado, Gregory R Keele, Jin Li, Qing Duan, Ge Li, Zhengrong Gao, Yun Li, Jianfeng Xu, William B Isaacs, Siqun Zheng, and Kathleen A Cooney

Subjects
Medicine, Science
Abstract

Prostate cancer is the most common non-skin cancer and the second leading cause of cancer related mortality for men in the United States. There is strong empirical and epidemiological evidence supporting a stronger role of genetics in early-onset prostate cancer. We performed a genome-wide association scan for early-onset prostate cancer. Novel aspects of this study include the focus on early-onset disease (defined as men with prostate cancer diagnosed before age 56 years) and use of publically available control genotype data from previous genome-wide association studies. We found genome-wide significant (p

Published
2014
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2. Genome-Wide Association Scan for Variants Associated with Early-Onset Prostate Cancer

Author

Zhengrong Gao, Anna Johnson, William B. Isaacs, Qing Duan, Yun Li, Kathleen A. Cooney, Ethan M. Lange, Ge Li, Jessica V. Ribado, Yurong Lu, Jianfeng Xu, Siqun Zheng, Yunfei Wang, Jin Li, Kimberly A. Zuhlke, and Gregory R. Keele

Subjects
Adult, Male, medicine.medical_specialty, Genotype, Urology, lcsh:Medicine, Genome-wide association study, Disease, Bioinformatics, Polymorphism, Single Nucleotide, 03 medical and health sciences, Prostate cancer, 0302 clinical medicine, Breast cancer, Epidemiology, medicine, Genome-Wide Association Studies, Genetics, Cancer Genetics, Medicine and Health Sciences, Humans, lcsh:Science, Genetic Association Studies, 030304 developmental biology, Genetic association, 0303 health sciences, Multidisciplinary, business.industry, Prostate Cancer, lcsh:R, Prostate Diseases, Cancer, Biology and Life Sciences, Computational Biology, Cancers and Neoplasms, Prostatic Neoplasms, Human Genetics, Middle Aged, medicine.disease, Genome Analysis, 3. Good health, Genitourinary Tract Tumors, Oncology, 030220 oncology & carcinogenesis, lcsh:Q, business, Research Article
Abstract

Prostate cancer is the most common non-skin cancer and the second leading cause of cancer related mortality for men in the United States. There is strong empirical and epidemiological evidence supporting a stronger role of genetics in early-onset prostate cancer. We performed a genome-wide association scan for early-onset prostate cancer. Novel aspects of this study include the focus on early-onset disease (defined as men with prostate cancer diagnosed before age 56 years) and use of publically available control genotype data from previous genome-wide association studies. We found genome-wide significant (p

Published
2014

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