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Rapid climate changes bear significant consequences on various aspects of our lives, notably by deteriorating living conditions in certain areas to such extent that inhabitants have no choice but flee. Despite recognition of this issue, the dynamics of the relationship between the environmental factors and the human mobility have yet to be thoroughly investigated. This study aims to explore the application of advanced remote sensing analytics for developing detailed climate indicators at a micro (district) level, and to examine the relationship between climate factors and internally displaced persons. After detailing our data sources and the analytics employed for indicator development, we discuss various types of events and their repercussions. Our findings corroborate that slow-onset and rapid-onset climate events differently impact society, and the responses hinge on the urgency precipitated by the detrimental aftermath of the extreme weather event and, most crucially, on people's capabilities. We also underscore the importance of data quality and availability for the socio-economic indicators to enhance future studies, given the intertwined associations between climate change, economic deprivation, and violent conflict.

Introduction: Early marriage, defined as marriage under the age of 18, is widely recognized as a human rights violation with deleterious consequences on women's health and well-being. It persists as a significant global public health issue, predominantly being practiced in South Asian countries. In Countries like Bangladesh, this practice contributes to an increase in early pregnancies among women of reproductive age, further exacerbating adverse maternal and child health outcomes. While certain predictors of early marriage are recognized, additional investigation is warranted due to diverse socio-economic and demographic circumstances. This study, therefore, aimed to identify the prevalence and determinants of early marriage among women in Bangladesh., Methods: This study included a total weighted sample of 18,228 married women aged 18 to 49 years, extracted from the most recent nationally representative Bangladesh Demography and Health Survey (2017-18). We estimated the survey weighted pooled prevalence of early marriage among women and stratified by their different characteristics. We used multilevel mixed-effect binary logistic regression model and estimated the odds ratios (ORs) with their 95% confidence intervals (CIs) to identify the individual-, household-, and community-level factors associated with early marriage practice. All analyses were performed by Stata software version 18., Results: Overall, 74.27% [95% CI: 73.15, 75.35] women got married before reaching the age of 18 years. Early marriage was more prevalent in Rajshahi (82.69%), Rangpur (81.35%), and Khulna division (79.32%). Women with higher education (OR = 0.10, 95% CI: 0.08, 0.12), husband's higher education (OR = 0.57, 95% CI: 0.48, 0.67), and non-Muslim women (OR = 0.46, 95% CI: 0.40, 0.52) were associated with a lower likelihood of experiencing early marriage. Compared to those household heads aged ≤35 years, the likelihood of early marriage among women was lower for those household heads aged 36-55 years (OR = 0.84, 95% CI: 0.76, 0.93) and >55 years (OR = 0.78, 95% CI: 0.69-0.88). Women aged 18-24 years (OR = 1.24, 95% CI: 1.10, 1.40), husbands with agricultural occupation (OR = 1.22, 95% CI:1.06, 1.41), middle wealth index level (OR = 1.14, 95% CI: 1.02, 1.28), family size five or more (OR = 1.21, 95% CI: 1.11, 1.31), and rural residence (OR = 1.17, 95% CI: 1.04, 1.30) were more likely to experience early marriage., Conclusion: This study underscores the alarming prevalence of early marriage among women in Bangladesh, with three-fourths experiencing early marriage, particularly in specific regions. Notably, women education and older household heads were significantly associated with a reduced likelihood of early marriage. Our findings suggest that culturally sensitive interventions should focus on empowering older household heads, alongside initiatives to increase awareness among younger household heads, and enhance education, particularly in rural and impoverished households. These efforts could potentially alter socio-cultural practices and reduce early marriage in Bangladesh., Competing Interests: The authors have declared that no competing interests exist., (Copyright: © 2024 Rashid et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)

Addition to the angiosperm flora provides essential insights into the biodiversity of a region, contributing to ecological understanding and conservation planning. Gafargaon subdistrict under Mymensingh district in Bangladesh represents a diverse population of angiosperms with a multifaceted ecosystem that demands re-evaluation of the existing angiosperm diversity of Gafargaon to update the status of angiosperm taxa and facilitate their conservation efforts. With this endeavor, a total of 100 angiosperm taxa belonging to 90 genera and 46 families were uncovered as additional occurrence in Gafargaon. The species in the area showcased a variety of life forms, including 63 herbs, 14 shrubs, 14 trees, and 9 climbers. Among the recorded taxa, Chamaecostus cuspidatus (Nees & Mart.) C.D. Specht & D.W. Stev. was selected for antidiabetic drug design endeavor based on citation frequency and ethnomedicinal evidence. A total of 41 phytochemicals of C. cuspidatus were screened virtually, targeting the Dipeptidyl peptidase 4 protein through structure-based drug design approach, which unveiled two lead compounds, such as Tigogenin (-9.0 kcal/mol) and Diosgenin (-8.5 kcal/mol). The lead candidates demonstrated favorable pharmacokinetic and pharmacodynamic properties with no major side effects. Molecular dynamics simulation revealed notable stability and structural compactness of the lead compounds. Principal component analysis and Gibbs free energy landscape further supported the results of molecular dynamics simulation. Molecular mechanics-based MM/GBSA approach unraveled higher free binding energies of Diosgenin (-47.36 kcal/mol) and Tigogenin (-46.70 kcal/mol) over Alogliptin (-46.32 kcal/mol). The outcome of the present investigation would enrich angiosperm flora of Gafargaon and shed light on the role of C. cuspidatus to develop novel antidiabetic therapeutics to combat diabetes., Competing Interests: The authors have declared that no competing interests exist., (Copyright: © 2024 Ahmed, Rahman. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)