1. Factors associated with contralateral liver hypertrophy after unilateral radioembolization for hepatocellular carcinoma
- Author
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Goebel, Juliane, Sulke, Maximilian, Lazik-Palm, Andrea, Goebel, Thomas, Dechêne, Alexander, Bellendorf, Alexander, Mueller, Stefan, Umutlu, Lale, and Theysohn, Jens
- Subjects
Male ,Physiology ,Medizin ,Cancer Treatment ,lcsh:Medicine ,Severity of Illness Index ,Diagnostic Radiology ,Animal Cells ,Immune Physiology ,Medicine and Health Sciences ,Yttrium Radioisotopes ,lcsh:Science ,Tomography ,Liver Diseases ,Radiology and Imaging ,Liver Neoplasms ,Age Factors ,Ascites ,Middle Aged ,Embolization, Therapeutic ,Body Fluids ,Tumor Burden ,Blood ,Cirrhosis ,Oncology ,Liver ,Female ,Anatomy ,Cellular Types ,Research Article ,Hepatomegaly ,Platelets ,Carcinoma, Hepatocellular ,Medizinische Fakultät » Universitätsklinikum Essen » Klinik für Nuklearmedizin ,Imaging Techniques ,Neuroimaging ,Gastroenterology and Hepatology ,Research and Analysis Methods ,Carcinomas ,Veins ,Medizinische Fakultät » Universitätsklinikum Essen » Klinik für Gastroenterologie und Hepatologie und Transplantationsmedizin ,Diagnostic Medicine ,Gastrointestinal Tumors ,ddc:61 ,Humans ,ddc:610 ,Portal Veins ,Aged ,Retrospective Studies ,Blood Cells ,Platelet Count ,lcsh:R ,Biology and Life Sciences ,Cancers and Neoplasms ,Hepatocellular Carcinoma ,Cell Biology ,Computed Axial Tomography ,Medizinische Fakultät » Universitätsklinikum Essen » Institut für Diagnostische und Interventionelle Radiologie und Neuroradiologie ,Cardiovascular Anatomy ,Blood Vessels ,lcsh:Q ,Radiopharmaceuticals ,Tomography, X-Ray Computed ,Spleen ,Neuroscience - Abstract
Introduction Radioembolization for the treatment of hepatocellular carcinoma (HCC) induces liver volume changes referred to as “atrophy-hypertrophy complex”. The aim of this study was to investigate lobar liver volume changes after unilateral radioembolization and to search for factors associated with hypertrophy of the untreated lobe. Materials and methods Seventy-five patients were retrospectively evaluated. Inclusion criteria were: (1) right-lobar radioembolization for unresectable unilateral HCC, (2) available liver computed tomography scans before, 1, 3, and at least 6 months after radioembolization. Baseline patient characteristics included clinical features, laboratory results, spleen volume, and liver computed tomography. Absolute and relative (referred to the whole liver volume) liver lobe volumes (LLV) as well as relative LLV (rLLV) change per month were evaluated and compared. Results Absolute and relative contralateral LLV continuously increased after radioembolization (p
- Published
- 2017