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Your search keyword '"Kulkarni, Hemant"' showing total 11 results
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11 results on '"Kulkarni, Hemant"'

2. Early identification of preterm neonates at birth with a Tablet App for the Simplified Gestational Age Score (T-SGAS) when ultrasound gestational age dating is unavailable: A validation study

Author

Patel, Archana B., primary, Kulkarni, Hemant, additional, Kurhe, Kunal, additional, Prakash, Amber, additional, Bhargav, Savita, additional, Parepalli, Suchita, additional, Fogleman, Elizabeth V., additional, Moore, Janet L., additional, Wallace, Dennis D., additional, and Hibberd, Patricia L., additional

Published
2020
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3. Soluble Forms of Intercellular and Vascular Cell Adhesion Molecules Independently Predict Progression to Type 2 Diabetes in Mexican American Families

Author

Kulkarni, Hemant, primary, Mamtani, Manju, additional, Peralta, Juan, additional, Almeida, Marcio, additional, Dyer, Thomas D., additional, Goring, Harald H., additional, Johnson, Matthew P., additional, Duggirala, Ravindranath, additional, Mahaney, Michael C., additional, Olvera, Rene L., additional, Almasy, Laura, additional, Glahn, David C., additional, Williams-Blangero, Sarah, additional, Curran, Joanne E., additional, and Blangero, John, additional

Published
2016
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5. Genetic Effects on DNA Methylation and Its Potential Relevance for Obesity in Mexican Americans

Author

Carless, Melanie A., primary, Kulkarni, Hemant, additional, Kos, Mark Z., additional, Charlesworth, Jac, additional, Peralta, Juan M., additional, Göring, Harald H. H., additional, Curran, Joanne E., additional, Almasy, Laura, additional, Dyer, Thomas D., additional, Comuzzie, Anthony G., additional, Mahaney, Michael C., additional, and Blangero, John, additional

Published
2013
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9. HIV-1 Disease-Influencing Effects Associated with ZNRD1, HCP5 and HLA-C Alleles Are Attributable Mainly to Either HLA-A10 or HLA-B*57 Alleles

Author

Catano, Gabriel, primary, Kulkarni, Hemant, additional, He, Weijing, additional, Marconi, Vincent C., additional, Agan, Brian K., additional, Landrum, Michael, additional, Anderson, Stephanie, additional, Delmar, Judith, additional, Telles, Vanessa, additional, Song, Li, additional, Castiblanco, John, additional, Clark, Robert A., additional, Dolan, Matthew J., additional, and Ahuja, Sunil K., additional

Published
2008
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10. CCL3L1-CCR5 Genotype Improves the Assessment of AIDS Risk in HIV-1-Infected Individuals

Author

Kulkarni, Hemant, primary, Agan, Brian K., additional, Marconi, Vincent C., additional, O'Connell, Robert J., additional, Camargo, Jose F., additional, He, Weijing, additional, Delmar, Judith, additional, Phelps, Kenneth R., additional, Crawford, George, additional, Clark, Robert A., additional, Dolan, Matthew J., additional, and Ahuja, Sunil K., additional

Published
2008
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11. Cumulative Viral Load and Virologic Decay Patterns after Antiretroviral Therapy in HIV-Infected Subjects Influence CD4 Recovery and AIDS.

Author

Marconi, Vincent C., Grandits, Greg, Okulicz, Jason F., Wortmann, Glenn, Ganesan, Anuradha, Crum-Cianflone, Nancy, Polis, Michael, Landrum, Michael, Dolan, Matthew J., Ahuja, Sunil K., Agan, Brian, and Kulkarni, Hemant

Subjects
MEDICAL care, VIRAL load, CD4 antigen, AIDS, HIGHLY active antiretroviral therapy, MEDICAL virology, REGRESSION analysis
Abstract

Background: The impact of viral load (VL) decay and cumulative VL on CD4 recovery and AIDS after highly-active antiretroviral therapy (HAART) is unknown. Methods and Findings: Three virologic kinetic parameters (first year and overall exponential VL decay constants, and first year VL slope) and cumulative VL during HAART were estimated for 2,278 patients who initiated HAART in the U.S. Military HIV Natural History Study. CD4 and VL trajectories were computed using linear and nonlinear Generalized Estimating Equations models. Multivariate Poisson and linear regression models were used to determine associations of VL parameters with CD4 recovery, adjusted for factors known to correlate with immune recovery. Cumulative VL higher than the sample median was independently associated with an increased risk of AIDS (relative risk 2.38, 95% confidence interval 1.56-3.62, p<0.001). Among patients with VL suppression, first year VL decay and slope were independent predictors of early CD4 recovery (p = 0.001) and overall gain (p<0.05). Despite VL suppression, those with slow decay during the first year of HAART as well as during the entire therapy period (overall), in general, gained less CD4 cells compared to the other subjects (133 vs. 195.4 cells/μL; p = 0.001) even after adjusting for potential confounders. Conclusions: In a cohort with free access to healthcare, independent of established predictors of AIDS and CD4 recovery during HAART, cumulative VL and virologic decay patterns were associated with AIDS and distinct aspects of CD4 reconstitution. [ABSTRACT FROM AUTHOR]

Published
2011
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