Search

Your search keyword '"Jeannig Berrou"' showing total 3 results
Start Over Author "Jeannig Berrou" Journal plos one
3 results on '"Jeannig Berrou"'

2. Natural killer cell function, an important target for infection and tumor protection, is impaired in type 2 diabetes.

Author

Jeannig Berrou, Sophie Fougeray, Marion Venot, Victor Chardiny, Jean-François Gautier, Nicolas Dulphy, Antoine Toubert, and Marie-Noëlle Peraldi

Subjects
Medicine, Science
Abstract

Patients with Type 2 diabetes (T2D) are highly susceptible to infection and have an increased incidence of some tumors, possibly due to immune system dysfunction. In the innate cellular immune system, Natural Killer (NK) lymphocytes are important effectors responsible for controlling infections and combating tumor development. We analyzed NK cell subsets in 51 patients with long-standing T2D. Compared with healthy blood donors, diabetic patients showed a profound decrease in both NKG2D-positive NK cells (44% vs. 55.5%, P

Published
2013
Full Text
View/download PDF

3. Natural killer cell function, an important target for infection and tumor protection, is impaired in type 2 diabetes

Author

Nicolas Dulphy, Jeannig Berrou, Victor Chardiny, Jean-François Gautier, Antoine Toubert, Marie-Noëlle Peraldi, Sophie Fougeray, and Marion Venot

Subjects
Male, Transcription, Genetic, NK cells, Clinical immunology, Interleukin 21, chemistry.chemical_compound, Endocrinology, 0302 clinical medicine, Neoplasms, Basic Cancer Research, Receptor, Immune Response, 0303 health sciences, Multidisciplinary, Immune cells, Degranulation, Tunicamycin, Middle Aged, Endoplasmic Reticulum Stress, 3. Good health, Killer Cells, Natural, Phenotype, Oncology, NK Cell Lectin-Like Receptor Subfamily K, Medicine, Female, Research Article, Adult, Clinical Research Design, Science, Immunology, 030209 endocrinology & metabolism, Biology, Infections, Young Adult, 03 medical and health sciences, Immune system, Humans, Aged, 030304 developmental biology, Diabetic Endocrinology, Natural Cytotoxicity Triggering Receptor 1, Diabetes Mellitus Type 2, NKG2D, Diabetes Mellitus, Type 2, chemistry, Metabolic Disorders, Hyperglycemia, Cancer research, Unfolded protein response
Abstract

Patients with Type 2 diabetes (T2D) are highly susceptible to infection and have an increased incidence of some tumors, possibly due to immune system dysfunction. In the innate cellular immune system, Natural Killer (NK) lymphocytes are important effectors responsible for controlling infections and combating tumor development. We analyzed NK cell subsets in 51 patients with long-standing T2D. Compared with healthy blood donors, diabetic patients showed a profound decrease in both NKG2D-positive NK cells (44% vs. 55.5%, P

Published
2013

Catalog

Books, media, physical & digital resources
See catalog results