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Your search keyword '"Gutiérrez, María A."' showing total 15 results
Start Over Author "Gutiérrez, María A." Journal plos one
15 results on '"Gutiérrez, María A."'

2. Effectiveness, safety/tolerability of OBV/PTV/r ± DSV in patients with HCV genotype 1 or 4 with/without HIV-1 co-infection, chronic kidney disease (CKD) stage IIIb-V and dialysis in Spanish clinical practice – Vie-KinD study

Author

Londoño, María-Carlota, primary, Riveiro-Barciela, Mar, additional, Ahumada, Adriana, additional, Muñoz-Gómez, Raquel, additional, Roget, Mercé, additional, Devesa-Medina, María J., additional, Serra, Miguel Ángel, additional, Navascués, Carmen A., additional, Baliellas, Carme, additional, Aldamiz-Echevarría, Teresa, additional, Gutiérrez, María L., additional, Polo-Lorduy, Benjamín, additional, Carmona, Isabel, additional, Benlloch, Salvador, additional, Bonet, Lucía, additional, García-Samaniego, Javier, additional, Jiménez-Pérez, Miguel, additional, Morán-Sánchez, Senador, additional, Castro, Ángeles, additional, Delgado, Manuel, additional, Gea-Rodríguez, Francisco, additional, Martín-Granizo, Ignacio, additional, Montes, María Luisa, additional, Morano, Luís, additional, Castaño, Manuel A., additional, de los Santos, Ignacio, additional, Laguno, Montserrat, additional, Losa, Juan Emilio, additional, Montero-Alonso, Marta, additional, Rivero, Antonio, additional, de Álvaro, Cristina, additional, Manzanares, Amanda, additional, Mallolas, Josep, additional, Barril, Guillermina, additional, González-Parra, Emilio, additional, and García-Buey, Luisa, additional

Published
2019
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3. Correction: Randomized prospective study evaluating tenofovir disoproxil fumarate prophylaxis against hepatitis B virus reactivation in anti-HBc-positive patients with rituximab-based regimens to treat hematologic malignancies: The Preblin study

Author

Buti, María, primary, Manzano, María L., additional, Morillas, Rosa M., additional, García-Retortillo, Montserrat, additional, Martín, Leticia, additional, Prieto, Martín, additional, Gutiérrez, María L., additional, Suárez, Emilio, additional, Rubio, Mariano Gómez, additional, López, Javier, additional, Castillo, Pilar, additional, Rodríguez, Manuel, additional, Zozaya, José M., additional, Simón, Miguel A., additional, Morano, Luis E., additional, Calleja, José L., additional, Yébenes, María, additional, and Esteban, Rafael, additional

Published
2018
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5. Randomized prospective study evaluating tenofovir disoproxil fumarate prophylaxis against hepatitis B virus reactivation in anti-HBc-positive patients with rituximab-based regimens to treat hematologic malignancies: The Preblin study

Author

Buti, María, primary, Manzano, María L., additional, Morillas, Rosa M., additional, García-Retortillo, Montserrat, additional, Martín, Leticia, additional, Prieto, Martín, additional, Gutiérrez, María L., additional, Suárez, Emilio, additional, Gómez Rubio, Mariano, additional, López, Javier, additional, Castillo, Pilar, additional, Rodríguez, Manuel, additional, Zozaya, José M., additional, Simón, Miguel A., additional, Morano, Luis E., additional, Calleja, José L., additional, Yébenes, María, additional, and Esteban, Rafael, additional

Published
2017
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6. HLA specificities are associated with prognosis in IGHV-mutated CLL-like high-count monoclonal B cell lymphocytosis

Author

García-Álvarez, María, primary, Alcoceba, Miguel, additional, López-Parra, Miriam, additional, Puig, Noemí, additional, Antón, Alicia, additional, Balanzategui, Ana, additional, Prieto-Conde, Isabel, additional, Jiménez, Cristina, additional, Sarasquete, María E., additional, Chillón, M. Carmen, additional, Gutiérrez, María Laura, additional, Corral, Rocío, additional, Alonso, José María, additional, Queizán, José Antonio, additional, Vidán, Julia, additional, Pardal, Emilia, additional, Peñarrubia, María Jesús, additional, Bastida, José M., additional, García-Sanz, Ramón, additional, Marín, Luis, additional, and González, Marcos, additional

Published
2017
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14. Chitosan Scaffolds Containing Calcium Phosphate Salts and rhBMP-2: In Vitro and In Vivo Testing for Bone Tissue Regeneration.

Author

Guzmán, Rodrigo, Nardecchia, Stefania, Gutiérrez, María C., Ferrer, María Luisa, Ramos, Viviana, del Monte, Francisco, Abarrategi, Ander, and López-Lacomba, José Luis

Subjects
CHITOSAN, TISSUE scaffolds, CALCIUM phosphate, RECOMBINANT proteins, BONE regeneration, BIOCOMPATIBILITY, HYDROXYAPATITE, IN vitro studies
Abstract

Numerous strategies that are currently used to regenerate bone depend on employing biocompatible materials exhibiting a scaffold structure. These scaffolds can be manufactured containing particular active compounds, such as hydroxyapatite precursors and/or different growth factors to enhance bone regeneration process. Herein, we have immobilized calcium phosphate salts (CPS) and bone morphogenetic protein 2 (BMP-2) – combined or alone – into chitosan scaffolds using ISISA process. We have analyzed whether the immobilized bone morphogenetic protein preserved its osteoinductive capability after manufacturing process as well as BMP-2 in vitro release kinetic. We have also studied both the in vitro and in vivo biocompatibility of the resulting scaffolds using a rabbit model. Results indicated that rhBMP-2 remained active in the scaffolds after the manufacturing process and that its release kinetic was different depending on the presence of CPS. In vitro and in vivo findings showed that cells grew more in scaffolds with both CPS and rhBMP-2 and that these scaffolds induced more bone formation in rabbit tibia. Thus chitosan scaffolds containing both CPS and rhBMP-2 were more osteoinductive than their counterparts alone indicating that could be useful for bone regeneration purposes, such as some applications in dentistry. [ABSTRACT FROM AUTHOR]

Published
2014
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15. The T309G MDM2 Gene Polymorphism Is a Novel Risk Factor for Proliferative Vitreoretinopathy.

Author

Pastor-Idoate, Salvador, Rodríguez-Hernández, Irene, Rojas, Jimena, Fernández, Itziar, García-Gutiérrez, María T., Ruiz-Moreno, José M., Rocha-Sousa, Amandio, Ramkissoon, Yashin, Harsum, Steven, MacLaren, Robert E., Charteris, David, VanMeurs, Jan C., González-Sarmiento, Rogelio, and Pastor, José C.

Subjects
PROLIFERATIVE vitreoretinopathy, GENETIC polymorphisms, RETINAL detachment, RETINAL surgery, P53 antioncogene, HEALTH risk assessment, MEDICAL geography, EPIDEMIOLOGY
Abstract

Proliferative vitreoretinopathy (PVR) is still the major cause of failure in retinal detachment (RD) surgery. It is believed that down-regulation in the p53 pathway could be an important key in PVR pathogenesis. The purpose was to evaluate the impact of T309G MDM2 polymorphism (rs2279744) in PVR. Distribution of T309G MDM2 genotypes among European subjects undergoing RD surgery was evaluated. Proportions of genotypes between subsamples from different countries were analyzed. Also, a genetic interaction between rs2279744 in MDM2 and rs1042522 in p53 gene was analyzed. Significant differences were observed comparing MDM2 genotype frequencies at position 309 of intron 1 between cases (GG: 21.6%, TG: 54.5%, TT: 23.8%) and controls (GG: 7.3%, TG: 43.9%, TT: 48.7%). The proportions of genotypes between sub-samples from different countries showed a significant difference. Distribution of GG genotype revealed differences in Spain (35.1–53.0)/(22.6–32.9), Portugal (39.0–74.4)/(21.4–38.9), Netherlands (40.6–66.3)/(25.3–38.8) and UK (37.5–62.4)/(23.3–34.2). The OR of G carriers in the global sample was 5.9 (95% CI: 3.2 to 11.2). The OR of G carriers from Spain and Portugal was 5.4 (95% CI: 2.2–12.7), whereas in the UK and the Netherlands was 7.3 (95% CI: 2.8–19.1). Results indicate that the G allele of rs2279744 is associated with a higher risk of developing PVR in patients undergoing a RD surgery. Further studies are necessary to understand the role of this SNP in the development of PVR. [ABSTRACT FROM AUTHOR]

Published
2013
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