Search

Your search keyword '"Fichorova, Raina N"' showing total 9 results
Start Over Author "Fichorova, Raina N" Journal plos one
9 results on '"Fichorova, Raina N"'

1. Randomized, placebo controlled phase I trial of the safety, pharmacokinetics, pharmacodynamics and acceptability of a 90 day tenofovir plus levonorgestrel vaginal ring used continuously or cyclically in women: The CONRAD 138 study

Author

Thurman, Andrea R., primary, Brache, Vivian, additional, Cochon, Leila, additional, Ouattara, Louise A., additional, Chandra, Neelima, additional, Jacot, Terry, additional, Yousefieh, Nazita, additional, Clark, Meredith R., additional, Peet, Melissa, additional, Hanif, Homaira, additional, Schwartz, Jill L., additional, Ju, Susan, additional, Marzinke, Mark A., additional, Erikson, David W., additional, Parikh, Urvi, additional, Herold, Betsy C., additional, Fichorova, Raina N., additional, Tolley, Elizabeth, additional, and Doncel, Gustavo F., additional

Published
2022
Full Text
View/download PDF

2. Results of a phase 1, randomized, placebo-controlled first-in-human trial of griffithsin formulated in a carrageenan vaginal gel

Author

Teleshova, Natalia, primary, Keller, Marla J., additional, Fernández Romero, José A., additional, Friedland, Barbara A., additional, Creasy, George W., additional, Plagianos, Marlena G., additional, Ray, Laurie, additional, Barnable, Patrick, additional, Kizima, Larisa, additional, Rodriguez, Aixa, additional, Cornejal, Nadjet, additional, Melo, Claudia, additional, Cruz Rodriguez, Gearoff, additional, Mukhopadhyay, Sampurna, additional, Calenda, Giulia, additional, Sinkar, Shweta U., additional, Bonnaire, Thierry, additional, Wesenberg, Asa, additional, Zhang, Shimin, additional, Kleinbeck, Kyle, additional, Palmer, Kenneth, additional, Alami, Mohcine, additional, O’Keefe, Barry R., additional, Gillevet, Patrick, additional, Hur, Hong, additional, Liang, Yupu, additional, Santone, Gabriela, additional, Fichorova, Raina N., additional, Kalir, Tamara, additional, and Zydowsky, Thomas M., additional

Published
2022
Full Text
View/download PDF

3. Aberrant cervical innate immunity predicts onset of dysbiosis and sexually transmitted infections in women of reproductive age

Author

Fichorova, Raina N., primary, Morrison, Charles S., additional, Chen, Pai-Lien, additional, Yamamoto, Hidemi S., additional, Govender, Yashini, additional, Junaid, Damilola, additional, Ryan, Stanthia, additional, Kwok, Cynthia, additional, Chipato, Tsungai, additional, Salata, Robert A., additional, and Doncel, Gustavo F., additional

Published
2020
Full Text
View/download PDF

6. Gene Expression Profiling of Human Vaginal Cells In Vitro Discriminates Compounds with Pro-Inflammatory and Mucosa-Altering Properties: Novel Biomarkers for Preclinical Testing of HIV Microbicide Candidates

Author

Zalenskaya, Irina A., primary, Joseph, Theresa, additional, Bavarva, Jasmin, additional, Yousefieh, Nazita, additional, Jackson, Suzanne S., additional, Fashemi, Titilayo, additional, Yamamoto, Hidemi S., additional, Settlage, Robert, additional, Fichorova, Raina N., additional, and Doncel, Gustavo F., additional

Published
2015
Full Text
View/download PDF

7. Endobiont Viruses Sensed by the Human Host – Beyond Conventional Antiparasitic Therapy

Author

Fichorova, Raina N., primary, Lee, Yujin, additional, Yamamoto, Hidemi S., additional, Takagi, Yuko, additional, Hayes, Gary R., additional, Goodman, Russell P., additional, Chepa-Lotrea, Xenia, additional, Buck, Olivia R., additional, Murray, Ryan, additional, Kula, Tomasz, additional, Beach, David H., additional, Singh, Bibhuti N., additional, and Nibert, Max L., additional

Published
2012
Full Text
View/download PDF

9. Elevated Endogenous Erythropoietin Concentrations Are Associated with Increased Risk of Brain Damage in Extremely Preterm Neonates.

Author

Korzeniewski, Steven J., Allred, Elizabeth, Logan, J. Wells, Fichorova, Raina N., Engelke, Stephen, Kuban, Karl C. K., O’Shea, T. Michael, Paneth, Nigel, Holm, Mari, Dammann, Olaf, Leviton, Alan, and null, null

Subjects
ERYTHROPOIETIN, BRAIN damage -- Risk factors, PREMATURE infants, INFLAMMATION, THERAPEUTIC use of proteins, LOGISTIC regression analysis
Abstract

Background: We sought to determine, in very preterm infants, whether elevated perinatal erythropoietin (EPO) concentrations are associated with increased risks of indicators of brain damage, and whether this risk differs by the co-occurrence or absence of intermittent or sustained systemic inflammation (ISSI). Methods: Protein concentrations were measured in blood collected from 786 infants born before the 28th week of gestation. EPO was measured on postnatal day 14, and 25 inflammation-related proteins were measured weekly during the first 2 postnatal weeks. We defined ISSI as a concentration in the top quartile of each of 25 inflammation-related proteins on two separate days a week apart. Hypererythropoietinemia (hyperEPO) was defined as the highest quartile for gestational age on postnatal day 14. Using logistic regression and multinomial logistic regression models, we compared risks of brain damage among neonates with hyperEPO only, ISSI only, and hyperEPO+ISSI, to those who had neither hyperEPO nor ISSI, adjusting for gestational age. Results: Newborns with hyperEPO, regardless of ISSI, were more than twice as likely as those without to have very low (< 55) Mental (OR 2.3; 95% CI 1.5-3.5) and/or Psychomotor (OR 2.4; 95% CI 1.6-3.7) Development Indices (MDI, PDI), and microcephaly at age two years (OR 2.4; 95%CI 1.5-3.8). Newborns with both hyperEPO and ISSI had significantly increased risks of ventriculomegaly, hemiparetic cerebral palsy, microcephaly, and MDI and PDI < 55 (ORs ranged from 2.2-6.3), but not hypoechoic lesions or other forms of cerebral palsy, relative to newborns with neither hyperEPO nor ISSI. Conclusion: hyperEPO, regardless of ISSI, is associated with elevated risks of very low MDI and PDI, and microcephaly, but not with any form of cerebral palsy. Children with both hyperEPO and ISSI are at higher risk than others of very low MDI and PDI, ventriculomegaly, hemiparetic cerebral palsy, and microcephaly. [ABSTRACT FROM AUTHOR]

Published
2015
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results