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Your search keyword '"Corbett, Elizabeth L."' showing total 20 results
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20 results on '"Corbett, Elizabeth L."'

1. Tuberculosis Immunoreactivity Surveillance in Malawi (Timasamala)—A protocol for a cross-sectional Mycobacterium tuberculosis immunoreactivity survey in Blantyre, Malawi

Author

Rickman, Hannah M., primary, Phiri, Mphatso D., additional, Feasey, Helena R. A., additional, Mbale, Hannah, additional, Nliwasa, Marriott, additional, Semphere, Robina, additional, Chagaluka, George, additional, Fielding, Katherine, additional, Mwandumba, Henry C., additional, Horton, Katherine C., additional, Nightingale, Emily S., additional, Henrion, Marc Y. R., additional, Mbendera, Kuzani, additional, Mpunga, James A., additional, Corbett, Elizabeth L., additional, and MacPherson, Peter, additional

Published
2024
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3. Effect of patient-delivered household contact tracing and prevention for tuberculosis: A household cluster-randomised trial in Malawi

Author

Kaswaswa, Kruger, primary, MacPherson, Peter, additional, Kumwenda, Moses, additional, Mpunga, James, additional, Thindwa, Deus, additional, Nliwasa, Marriott, additional, Mwapasa, Mphatso, additional, Odland, Jon, additional, Tomoka, Tamiwe, additional, Chipungu, Geoffrey, additional, Mukaka, Mavuto, additional, and Corbett, Elizabeth L., additional

Published
2022
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4. Neighbourhood prevalence-to-notification ratios for adult bacteriologically-confirmed tuberculosis reveals hotspots of underdiagnosis in Blantyre, Malawi

Author

Khundi, McEwen, primary, Carpenter, James R., additional, Corbett, Elizabeth L., additional, Feasey, Helena R. A., additional, Soko, Rebecca Nzawa, additional, Nliwasa, Marriott, additional, Twabi, Hussein, additional, Chiume, Lingstone, additional, Burke, Rachael M., additional, Horton, Katherine C., additional, Dodd, Peter J., additional, Cohen, Ted, additional, and MacPherson, Peter, additional

Published
2022
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5. Design and protocol for a cluster randomised trial of enhanced diagnostics for tuberculosis screening among people living with HIV in hospital in Malawi (CASTLE study)

Author

Burke, Rachael M., primary, Nyirenda, Saulos, additional, Twabi, Hussein H., additional, Nliwasa, Marriott, additional, Joekes, Elizabeth, additional, Walker, Naomi, additional, Nyirenda, Rose, additional, Gupta-Wright, Ankur, additional, Fielding, Katherine, additional, MacPherson, Peter, additional, and Corbett, Elizabeth L., additional

Published
2022
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6. Provider-initiated HIV testing and TB screening in the era of universal coverage: Are the right people being reached? A cohort study in Blantyre, Malawi

Author

Mair, Luke, primary, Corbett, Elizabeth L., additional, Feasey, Helena R. A., additional, Kamchedzera, Wala, additional, Khundi, McEwen, additional, Lalloo, David G., additional, Maheswaran, Hendramoorthy, additional, Nliwasa, Marriott, additional, Squire, S. Bertel, additional, Webb, Emily L., additional, and MacPherson, Peter, additional

Published
2020
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7. Economic costs and health-related quality of life outcomes of hospitalised patients with high HIV prevalence: A prospective hospital cohort study in Malawi

Author

Maheswaran, Hendramoorthy, Petrou, Stavros, Cohen, Danielle, MacPherson, Peter, Kumwenda, Felistas, Lalloo, David G., Corbett, Elizabeth L., and Clarke, Aileen

Subjects
RNA viruses, Bacterial Diseases, Male, Malawi, Financial Management, Economics, lcsh:Medicine, Social Sciences, HIV Infections, wc_503, Pathology and Laboratory Medicine, Immunodeficiency Viruses, Medicine and Health Sciences, Prevalence, Prospective Studies, lcsh:Science, HIV diagnosis and management, Middle Aged, Hospitals, Hospitalization, Infectious Diseases, Anti-Retroviral Agents, Medical Microbiology, Viral Pathogens, Viruses, Costs and Cost Analysis, Tuberculosis Diagnosis and Management, Female, Pathogens, Research Article, Adult, Adolescent, 41b6e438, Microbiology, d67ea616, Diagnostic Medicine, Retroviruses, Indirect Costs, Tuberculosis, Humans, Microbial Pathogens, lcsh:R, Lentivirus, Organisms, Biology and Life Sciences, HIV, Tropical Diseases, Miliary Tuberculosis, Health Care, Health Care Facilities, Quality of Life, lcsh:Q, Finance
Abstract

Introduction: Although HIV infection and its associated co-morbidities remain the commonest reason for hospitalisation in Africa, their impact on economic costs and health-related quality of life (HRQoL) are not well understood. This information is essential for decision-makers to make informed choices about how to best scale-up anti-retroviral treatment (ART) programmes. This study aimed to quantify the impact of HIV infection and ART on economic outcomes in a prospective cohort of hospitalised patients with high HIV prevalence.\ud \ud Methods: Sequential medical admissions to Queen Elizabeth Central Hospital, Malawi, between June-December 2014 were followed until discharge, with standardised classification of medical diagnosis and estimation of healthcare resources used. Primary costing studies estimated total health provider cost by medical diagnosis. Participants were interviewed to establish direct non-medical and indirect costs. Costs were adjusted to 2014 US$ and INT$. HRQoL was measured using the EuroQol EQ-5D. Multivariable analyses estimated predictors of economic outcomes.\ud \ud Results: Of 892 eligible participants, 80.4% (647/892) were recruited and medical notes found. In total, 447/647 (69.1%) participants were HIV-positive, 339/447 (75.8%) were on ART prior to admission, and 134/647 (20.7%) died in hospital. Mean duration of admission for HIV-positive participants not on ART and HIV-positive participants on ART was 15.0 days (95%CI: 12.0-18.0) and 12.2 days (95%CI: 10.8-13.7) respectively, compared to 10.8 days (95%CI: 8.8-12.8) for HIV-negative participants. Mean total provider cost per hospital admission was US$74.78 (bootstrap 95%CI: US$25.41-US$124.15) higher for HIV-positive than HIV-negative participants. Amongst HIV-positive participants, the mean total provider cost was US$106.87 (bootstrap 95%CI: US$25.09-US$106.87) lower for those on ART than for those not on ART. The mean total direct non-medical and indirect cost per hospital admission was US$87.84. EQ-5D utility scores were lower amongst HIV-positive participants, but not significantly different between those on and not on ART. \ud \ud Conclusions: HIV-related hospital care poses substantial financial burdens on health systems and patients; however, per-admission costs are substantially lower for those already initiated onto ART prior to admission. These potential cost savings could offset some of the additional resources needed to provide universal access to ART.

Published
2018

8. Costs of facility-based HIV testing in Malawi, Zambia and Zimbabwe

Author

Mwenge, Lawrence, primary, Sande, Linda, additional, Mangenah, Collin, additional, Ahmed, Nurilign, additional, Kanema, Sarah, additional, d’Elbée, Marc, additional, Sibanda, Euphemia, additional, Kalua, Thokozani, additional, Ncube, Gertrude, additional, Johnson, Cheryl C., additional, Hatzold, Karin, additional, Cowan, Frances M., additional, Corbett, Elizabeth L., additional, Ayles, Helen, additional, Maheswaran, Hendramoorthy, additional, and Terris-Prestholt, Fern, additional

Published
2017
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9. Treatment-Seeking for Tuberculosis-Suggestive Symptoms: A Reflection on the Role of Human Agency in the Context of Universal Health Coverage in Malawi

Author

Kumwenda, Moses, Desmond, Nicola, Hart, Graham, Choko, Augustine, Chipungu, Geoffrey A., Nyirenda, Deborah, Shand, Tim, Corbett, Elizabeth L., Chikovore, Jeremiah, Department of Public Health and Family Medicine, and Faculty of Health Sciences

Subjects
Bacterial Diseases, Male, Malawi, Fever, Physiology, Health Personnel, Health Behavior, lcsh:Medicine, Pathology and Laboratory Medicine, Drug interactions, 26bc6fb8, Geographical Locations, Antimalarials, Signs and Symptoms, Medicine and Health Sciences, Coughing, Humans, Tuberculosis, Tuberculosis diagnosis and management, Community Health Services, Health care providers, lcsh:Science, f0e481db, Pharmacology, Masculinity, Fluorenes, Artemether, Lumefantrine Drug Combination, lcsh:R, Biology and Life Sciences, Health care facilities, HIV diagnosis and management, Focus Groups, Patient Acceptance of Health Care, Tropical Diseases, Diagnostic medicine, Artemisinins, Health Care, Drug Combinations, Infectious Diseases, Cough, Ethanolamines, People and Places, Africa, Chronic Disease, wf_220, Female, lcsh:Q, Physiological Processes, Research Article
Abstract

Tuberculosis (TB) is highly infectious and one of the leading killers globally. Several studies from sub-Saharan Africa highlight health systems challenges that affect ability to cope with existing disease burden, including TB, although most of these employ survey-type approaches. Consequently, few address community or patient perspectives and experiences. At the same time, understanding of the mechanisms by which the health systems challenges translate into seeking or avoidance of formal health care remains limited. This paper applies the notion of human agency to examine the ways people who have symptoms suggestive of TB respond to and deal with the symptoms vis-à-vis major challenges inherent within health delivery systems. Empirical data were drawn from a qualitative study exploring the ways in which notions of masculinity affect engagement with care, including men’s well-documented tendency to delay in seeking care for TB symptoms. The study was carried out in three high-density locales of urban Blantyre, Malawi. Data were collected in March 2011 –March 2012 using focus group discussions, of which eight (mixed sex = two; female only = three; male only = three) were with 74 ordinary community members, and two (both mixed sex) were with 20 health workers; and in-depth interviews with 20 TB patients (female = 14) and 20 un-investigated chronic coughers (female = eight). The research process employed a modified version of grounded theory. Data were coded using a coding scheme that was initially generated from the study aims and subsequently progressively amended to incorporate concepts emerging during the analysis. Coded data were retrieved, re-read, and broken down and reconnected iteratively to generate themes. A myriad of problems were described for health systems at the primary health care level, centring largely on shortages of resources (human, equipment, and drugs) and unprofessional conduct by health care providers. Participants consistently pointed out how the problems could drive patients from promptly reporting symptoms at primary healthcare centres. The accounts suggest that in responding to illness symptoms including those suggestive of TB, patients navigate their options taking into cognisance past and current experiences with formal health systems. Understanding and factoring in the mediating role of such ‘agency’ is critical when implementing efforts to promote timely response to TB-suggestive symptoms.

Published
2016

10. Initial Accuracy of HIV Rapid Test Kits Stored in Suboptimal Conditions and Validity of Delayed Reading of Oral Fluid Tests

Author

Choko, Augustine T., primary, Taegtmeyer, Miriam, additional, MacPherson, Peter, additional, Cocker, Derek, additional, Khundi, McEwen, additional, Thindwa, Deus, additional, Sambakunsi, Rodrick S., additional, Kumwenda, Moses K., additional, Chiumya, Kondwani, additional, Malema, Owen, additional, Makombe, Simon D., additional, Webb, Emily L., additional, and Corbett, Elizabeth L., additional

Published
2016
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11. The Sensitivity and Specificity of Loop-Mediated Isothermal Amplification (LAMP) Assay for Tuberculosis Diagnosis in Adults with Chronic Cough in Malawi

Author

Nliwasa, Marriott, primary, MacPherson, Peter, additional, Chisala, Palesa, additional, Kamdolozi, Mercy, additional, Khundi, McEwen, additional, Kaswaswa, Kruger, additional, Mwapasa, Mphatso, additional, Msefula, Chisomo, additional, Sohn, Hojoon, additional, Flach, Clare, additional, and Corbett, Elizabeth L., additional

Published
2016
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14. Enhancing Psychosocial Support for HIV Positive Adolescents in Harare, Zimbabwe

Author

Mavhu, Webster, primary, Berwick, Jessica, additional, Chirawu, Petronella, additional, Makamba, Memory, additional, Copas, Andrew, additional, Dirawo, Jeffrey, additional, Willis, Nicola, additional, Araya, Ricardo, additional, Abas, Melanie A., additional, Corbett, Elizabeth L., additional, Mungofa, Stanley, additional, Laver, Susan M., additional, and Cowan, Frances M., additional

Published
2013
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15. Determinants and Consequences of Failure of Linkage to Antiretroviral Therapy at Primary Care Level in Blantyre, Malawi: A Prospective Cohort Study

Author

MacPherson, Peter, primary, Corbett, Elizabeth L., additional, Makombe, Simon D., additional, van Oosterhout, Joep J., additional, Manda, Eddie, additional, Choko, Augustine T., additional, Thindwa, Deus, additional, Squire, S. Bertel, additional, Mann, Gillian H., additional, and Lalloo, David G., additional

Published
2012
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16. High Prevalence of Tuberculosis and Serious Bloodstream Infections in Ambulatory Individuals Presenting for Antiretroviral Therapy in Malawi

Author

Bedell, Richard A., primary, Anderson, Suzanne T. B., additional, van Lettow, Monique, additional, Åkesson, Ann, additional, Corbett, Elizabeth L., additional, Kumwenda, Moses, additional, Chan, Adrienne K., additional, Heyderman, Robert S., additional, Zachariah, Rony, additional, Harries, Anthony D., additional, and Ramsay, Andrew R., additional

Published
2012
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17. Detection of Mycobacterium tuberculosis in Sputum by Gas Chromatography-Mass Spectrometry of Methyl Mycocerosates Released by Thermochemolysis

Author

O'Sullivan, Denise M., primary, Nicoara, Simona C., additional, Mutetwa, Reggie, additional, Mungofa, Stanley, additional, Lee, Oona Y-C., additional, Minnikin, David E., additional, Bardwell, Max W., additional, Corbett, Elizabeth L., additional, McNerney, Ruth, additional, and Morgan, Geraint H., additional

Published
2012
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19. Stigmatising Attitudes among People Offered Home-Based HIV Testing and Counselling in Blantyre, Malawi: Construction and Analysis of a Stigma Scale

Author

MacPherson, Peter, primary, Webb, Emily L., additional, Choko, Augustine T., additional, Desmond, Nicola, additional, Chavula, Kondwani, additional, Napierala Mavedzenge, Sue, additional, Makombe, Simon D., additional, Chunda, Treza, additional, Squire, S. Bertel, additional, and Corbett, Elizabeth L., additional

Published
2011
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20. The Risk and Timing of Tuberculosis Diagnosed in Smear-Negative TB Suspects: A 12 Month Cohort Study in Harare, Zimbabwe

Author

Dimairo, Munyaradzi, primary, MacPherson, Peter, additional, Bandason, Tsitsi, additional, Zezai, Abbas, additional, Munyati, Shungu S., additional, Butterworth, Anthony E., additional, Mungofa, Stanley, additional, Rusikaniko, Simba, additional, Fielding, Katherine, additional, Mason, Peter R., additional, and Corbett, Elizabeth L., additional

Published
2010
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