10 results on '"Caroline Masquillier"'
Search Results
2. Long-term retention and predictors of attrition for key populations receiving antiretroviral treatment through community-based ART in Benue State Nigeria: A retrospective cohort study.
- Author
-
Olujuwon Ibiloye, Plang Jwanle, Caroline Masquillier, Sara Van Belle, Ekere Jaachi, Olubunmi Amoo, Ahmed Isah, Temiwoluwa Omole, Jay Osi Samuel, Josefien van Olmen, Lutgarde Lynen, Prosper Okonkwo, and Tom Decroo
- Subjects
Medicine ,Science - Abstract
BackgroundKey populations (KP) are disproportionately infected with HIV and experience barriers to HIV care. KP include men who have sex with men (MSM), female sex workers (FSW), persons who inject drugs (PWID) and transgender people (TG). We implemented three different approaches to the delivery of community-based antiretroviral therapy for KP (KP-CBART) in Benue State Nigeria, including One Stop Shop clinics (OSS), community drop-in-centres (DIC), and outreach venues. OSS are community-based health facilities serving KP only. DIC are small facilities led by lay healthcare providers and supported by an outreach team. Outreach venues are places in the community served by the outreach team. We studied long-term attrition of KP and virological non-suppression.MethodThis is a retrospective cohort study of KP living with HIV (KPLHIV) starting ART between 2016 and 2019 in 3 0SS, 2 DIC and 8 outreach venues. Attrition included lost to follow-up (LTFU) and death. A viral load >1000 copies/mL showed viral non-suppression. Survival analysis was used to assess retention on ART. Cox regression and Firth logistic regression were used to assess risk factors for attrition and virological non-suppression respectively.ResultOf 3495 KPLHIV initiated on ART in KP-CBART, 51.8% (n = 1812) were enrolled in OSS, 28.1% (n = 982) in DIC, and 20.1% (n = 701) through outreach venues. The majority of participants were FSW-54.2% (n = 1896), while 29.8% (n = 1040), 15.8% (n = 551) and 0.2% (n = 8) were MSM, PWID, and TG respectively. The overall retention in the programme was 63.5%, 55.4%, 51.2%, and 46.7% at 1 year, 2 years, 3 years, and 4 years on ART. Of 1650 with attrition, 2.5% (n = 41) died and others were LTFU. Once adjusted for other factors (age, sex, place of residence, year of ART enrollment, WHO clinical stage, type of KP group, and KP-CBART approach), KP-CBART approach did not predict attrition. MSM were at a higher risk of attrition (vs FSW; adjusted hazard ratio (aHR) 1.27; 95%CI: 1.14-1.42). Of 3495 patients, 48.4% (n = 1691) had a viral load test. Of those, 97.8% (n = 1654) were virally suppressed.ConclusionAlthough long-term retention in care is low, the virological suppression was optimal for KP on ART and retained in community-based ART care. However, viral load testing coverage was sub-optimal. Future research should explore the perspectives of clients on reasons for LTFU and how to adapt approach to CBART to meet individual client needs.
- Published
- 2021
- Full Text
- View/download PDF
3. HIV/AIDS Competent Households: Interaction between a Health-Enabling Environment and Community-Based Treatment Adherence Support for People Living with HIV/AIDS in South Africa.
- Author
-
Caroline Masquillier, Edwin Wouters, Dimitri Mortelmans, Brian van Wyk, Harry Hausler, and Wim Van Damme
- Subjects
Medicine ,Science - Abstract
In the context of severe human resource shortages in HIV care, task-shifting and especially community-based support are increasingly being cited as potential means of providing durable care to chronic HIV patients. Socio-ecological theory clearly stipulates that-in all social interventions-the interrelatedness and interdependency between individuals and their immediate social contexts should be taken into account. People living with HIV/AIDS (PLWHA) seldom live in isolation, yet community-based interventions for supporting chronic HIV patients have largely ignored the social contexts in which they are implemented. Research is thus required to investigate such community-based support within its context. The aim of this study is to address this research gap by examining the way in which HIV/AIDS competence in the household hampers or facilitates community-based treatment adherence support. The data was analyzed carefully in accordance with the Grounded Theory procedures, using Nvivo 10. More specifically, we analyzed field notes from participatory observations conducted during 48 community-based treatment adherence support sessions in townships on the outskirts of Cape Town, transcripts of 32 audio-recorded in-depth interviews with PLWHA and transcripts of 4 focus group discussions with 36 community health workers (CHWs). Despite the fact that the CHWs try to present themselves as not being openly associated with HIV/AIDS services, results show that the presence of a CHW is often seen as a marker of the disease. Depending on the HIV/AIDS competence in the household, this association can challenge the patient's hybrid identity management and his/her attempt to regulate the interference of the household in the disease management. The results deepen our understanding of how the degree of HIV/AIDS competence present in a PLWHA's household affects the manner in which the CHW can perform his or her job and the associated benefits for the patient and his/her household members. In this respect, a household with a high level of HIV/AIDS competence will be more receptive to treatment adherence support, as the patient is more likely to allow interaction between the CHW and the household. In contrast, in a household which exhibits limited characteristics of HIV/AIDS competence, interaction with the treatment adherence supporter may be difficult in the beginning. In such a situation, visits from the CHW threaten the hybrid identity management. If the CHW handles this situation cautiously and the patient-acting as a gate keeper-allows interaction, the CHW may be able to help the household develop towards HIV/AIDS competence. This would have a more added value compared to a household which was more HIV/AIDS competent from the outset. This study indicates that pre-existing dynamics in a patient's social environment, such as the HIV/AIDS competence of the household, should be taken into account when designing community-based treatment adherence programs in order to provide long-term quality care, treatment and support in the context of human resource shortages.
- Published
- 2016
- Full Text
- View/download PDF
4. Who Should We Target? The Impact of Individual and Family Characteristics on the Expressed Need for Community-Based Treatment Support in HIV Patients in South Africa.
- Author
-
Edwin Wouters, Frederik le Roux Booysen, and Caroline Masquillier
- Subjects
Medicine ,Science - Abstract
Reviews of impact evaluations of community-based health workers and peer support groups highlight the considerable variability in the effectiveness of such support in improving antiretroviral treatment (ART) outcomes. Evidence indicates that community-based support interventions targeting patients known to be at risk will probably display better results than generic interventions aimed at the entire population of people living with HIV. It is however difficult to identify these at-risk populations, rendering knowledge on the characteristics of patients groups who are in need of community-based support a clear research priority. The current study aims to address the knowledge gap by exploring the predictors of the willingness to (1) receive the support from a community-based health worker or (2) to participate in a support group in public sector ART programme of the Free State Province of South Africa. Based on the Individual-Family-Community framework for HIV research, the study employs a comprehensive approach by not only testing classical individual-level but also family-level predictors of the willingness to receive community-based support. In addition to individual-level predictors-such as age, health status and coping styles-our analysis demonstrated the importance of family characteristics. The results indicated that discrepancies in the family's changeability level were an important predictor of the demand for community-based support services. Conversely, the findings indicated that patients living in a family more flexible than deemed ideal are more likely to require the support of a community health worker. The current study expands theory by indicating the need to acknowledge all social ecological levels in the study of chronic HIV care. The detection of both individual level and family level determinants of the expressed need for community-based support can inform health policy to devise strategies to target scarce resources to those vulnerable patients who report the greatest need for this support. In this way, the study results are a first step in an attempt to move away from generic, broad based community-based interventions towards community support that is tailored to the patient needs at both the individual and family level.
- Published
- 2016
- Full Text
- View/download PDF
5. Measuring health-related quality of life of HIV-positive adolescents in resource-constrained settings.
- Author
-
Caroline Masquillier, Edwin Wouters, Jasna Loos, and Christiana Nöstlinger
- Subjects
Medicine ,Science - Abstract
Background and objectivesAccess to antiretroviral treatment among adolescents living with HIV (ALH) is increasing. Health-related quality of life (HRQOL) is relevant for monitoring the impact of the disease on both well-being and treatment outcomes. However, adequate screening tools to assess HRQOL in low-resource settings are scarce. This study aims to fill this research gap, by 1) assessing the psychometric properties and reliability of an Eastern African English version of a European HRQOL scale for adolescents (KIDSCREEN) and 2) determining which version of the KIDSCREEN (52-, 27- and 10-item version) is most suitable for low-resource settings.MethodsThe KIDSCREEN was translated into Eastern African English, Luganda (Uganda) and Dholuo (Kenya) according to standard procedures. The reconciled version was administered in 2011 to ALH aged 13-17 in Kenya (n = 283) and Uganda (n = 299). All three KIDSCREEN versions were fitted to the data with confirmatory factor analysis (CFA). After comparison, the most suitable version was adapted based on the CFA outcomes utilizing the results of previous formative research. In order to develop a general HRQOL factor, a second-order measurement model was fitted to the data.ResultsThe CFA results showed that without adjustments, the KIDSCREEN cannot be used for measuring the HRQOL of HIV-positive adolescents. After comparison, the most suitable version for low-resource settings--the 27-item version--was adapted further. The introduction of a negative wording factor was required for the Dholuo model. The Dholuo (CFI: 0.93; RMSEA: 0.039) and the Luganda model (CFI: 0.90; RMSEA: 0.052) showed a good fit. All cronbach's alphas of the factors were 0.70 or above. The alpha value of the Dholuo and Lugandan HRQOL second-order factor was respectively 0.84 and 0.87.ConclusionsThe study showed that the adapted KIDSCREEN-27 is an adequate tool for measuring HRQOL in low-resource settings with high HIV prevalence.
- Published
- 2012
- Full Text
- View/download PDF
6. Long-term retention and predictors of attrition for key populations receiving antiretroviral treatment through community-based ART in Benue State Nigeria: A retrospective cohort study
- Author
-
Sara Van Belle, Caroline Masquillier, Jay Osi Samuel, Olujuwon Ibiloye, Olubunmi Amoo, Tom Decroo, Temiwoluwa Omole, Prosper Okonkwo, Plang Jwanle, Ekere Jaachi, Josefien van Olmen, Lutgarde Lynen, and Ahmed Isah
- Subjects
Male ,RNA viruses ,HIV Infections ,Logistic regression ,Pathology and Laboratory Medicine ,Men who have sex with men ,Geographical Locations ,Sexual and Gender Minorities ,Immunodeficiency Viruses ,Risk Factors ,Medicine and Health Sciences ,Attrition ,Public and Occupational Health ,Virus Testing ,Multidisciplinary ,Hazard ratio ,HIV diagnosis and management ,Middle Aged ,Viral Load ,Vaccination and Immunization ,Outreach ,Anti-Retroviral Agents ,Medical Microbiology ,Viral Pathogens ,Viruses ,Medicine ,Infectious diseases ,Female ,Pathogens ,Viral load ,Research Article ,Adult ,Medical conditions ,Science ,Immunology ,Nigeria ,Antiretroviral Therapy ,Men WHO Have Sex with Men ,Viral diseases ,Microbiology ,Medication Adherence ,Antiviral Therapy ,Diagnostic Medicine ,Virology ,Retroviruses ,medicine ,Humans ,Microbial Pathogens ,Retrospective Studies ,Sex Workers ,Proportional hazards model ,business.industry ,Lentivirus ,Organisms ,Biology and Life Sciences ,HIV ,Retrospective cohort study ,medicine.disease ,CD4 Lymphocyte Count ,People and Places ,Africa ,HIV-1 ,Population Groupings ,Human medicine ,Preventive Medicine ,business ,Viral Transmission and Infection ,Demography ,Sexuality Groupings - Abstract
Background Key populations (KP) are disproportionately infected with HIV and experience barriers to HIV care. KP include men who have sex with men (MSM), female sex workers (FSW), persons who inject drugs (PWID) and transgender people (TG). We implemented three different approaches to the delivery of community-based antiretroviral therapy for KP (KP-CBART) in Benue State Nigeria, including One Stop Shop clinics (OSS), community drop-in-centres (DIC), and outreach venues. OSS are community-based health facilities serving KP only. DIC are small facilities led by lay healthcare providers and supported by an outreach team. Outreach venues are places in the community served by the outreach team. We studied long-term attrition of KP and virological non-suppression. Method This is a retrospective cohort study of KP living with HIV (KPLHIV) starting ART between 2016 and 2019 in 3 0SS, 2 DIC and 8 outreach venues. Attrition included lost to follow-up (LTFU) and death. A viral load >1000 copies/mL showed viral non-suppression. Survival analysis was used to assess retention on ART. Cox regression and Firth logistic regression were used to assess risk factors for attrition and virological non-suppression respectively. Result Of 3495 KPLHIV initiated on ART in KP-CBART, 51.8% (n = 1812) were enrolled in OSS, 28.1% (n = 982) in DIC, and 20.1% (n = 701) through outreach venues. The majority of participants were FSW—54.2% (n = 1896), while 29.8% (n = 1040), 15.8% (n = 551) and 0.2% (n = 8) were MSM, PWID, and TG respectively. The overall retention in the programme was 63.5%, 55.4%, 51.2%, and 46.7% at 1 year, 2 years, 3 years, and 4 years on ART. Of 1650 with attrition, 2.5% (n = 41) died and others were LTFU. Once adjusted for other factors (age, sex, place of residence, year of ART enrollment, WHO clinical stage, type of KP group, and KP-CBART approach), KP-CBART approach did not predict attrition. MSM were at a higher risk of attrition (vs FSW; adjusted hazard ratio (aHR) 1.27; 95%CI: 1.14–1.42). Of 3495 patients, 48.4% (n = 1691) had a viral load test. Of those, 97.8% (n = 1654) were virally suppressed. Conclusion Although long-term retention in care is low, the virological suppression was optimal for KP on ART and retained in community-based ART care. However, viral load testing coverage was sub-optimal. Future research should explore the perspectives of clients on reasons for LTFU and how to adapt approach to CBART to meet individual client needs.
- Published
- 2021
7. Who falls between the cracks? Identifying eligible PrEP users among people with Sub-Saharan African migration background living in Antwerp, Belgium
- Author
-
Caroline Masquillier, Ella Van Landeghem, Bea Vuylsteke, Christiana Nöstlinger, Edwin Wouters, Thijs Reyniers, and Veerle Buffel
- Subjects
RNA viruses ,Male ,Epidemiology ,Economics ,Vulnerability ,Social Sciences ,HIV Infections ,Logistic regression ,Pathology and Laboratory Medicine ,Geographical locations ,Men who have sex with men ,Pre-exposure prophylaxis ,Sociology ,Immunodeficiency Viruses ,Belgium ,Medicine and Health Sciences ,Public and Occupational Health ,Transients and Migrants ,education.field_of_study ,Multidisciplinary ,Europe ,Geography ,Medical Microbiology ,HIV epidemiology ,Viral Pathogens ,Viruses ,Medicine ,Female ,Pathogens ,Research Article ,Adult ,Sub saharan ,Anti-HIV Agents ,Science ,Population ,Men WHO Have Sex with Men ,Interpersonal communication ,Microbiology ,Health Economics ,Risk-Taking ,Retroviruses ,Humans ,European Union ,education ,Microbial Pathogens ,Africa South of the Sahara ,Prophylaxis ,Lentivirus ,Organisms ,Biology and Life Sciences ,HIV ,Educational attainment ,Health Care ,Cross-Sectional Studies ,Medical Risk Factors ,Pre-Exposure Prophylaxis ,Population Groupings ,Human medicine ,Preventive Medicine ,People and places ,Finance ,Demography ,Health Insurance ,Sexuality Groupings - Abstract
Introduction This study produces an estimate of the proportion of eligible PrEP users among people of Sub-Saharan African background based on the Belgian PrEP eligibility criteria and examines associations with socio-economic and demographic characteristics. Methods We performed logistic regression analysis on data of a representative community-based survey conducted among Sub-Saharan African communities (n = 685) living in Antwerp. Results Almost a third (30.3%) of the respondents were eligible to use PrEP. Those who were male, single, lower educated, undocumented, and had experienced forced sex were more likely to be eligible for PrEP use. The findings highlight the importance of taking intra-, interpersonal and structural HIV risk factors into account. Conclusions The study shows high unmet PrEP needs in this population, especially among those with high vulnerability for HIV acquisition. A better understanding of barriers to PrEP use in this population group is needed to allow for equitable access.
- Published
- 2021
8. Who Should We Target? The Impact of Individual and Family Characteristics on the Expressed Need for Community-Based Treatment Support in HIV Patients in South Africa
- Author
-
Caroline Masquillier, Edwin Wouters, and Frederik Booysen
- Subjects
RNA viruses ,Male ,Health Status ,medicine.medical_treatment ,Psychological intervention ,lcsh:Medicine ,HIV Infections ,Peer support ,Pathology and Laboratory Medicine ,South Africa ,0302 clinical medicine ,Sociology ,Immunodeficiency Viruses ,Adaptation, Psychological ,Medicine and Health Sciences ,Public and Occupational Health ,030212 general & internal medicine ,lcsh:Science ,Randomized Controlled Trials as Topic ,Community Health Workers ,Family Characteristics ,Multidisciplinary ,Ecology ,Public sector ,Age Factors ,Middle Aged ,Vaccination and Immunization ,Community Ecology ,Anti-Retroviral Agents ,Medical Microbiology ,Viral Pathogens ,Viruses ,Community health ,Income ,Female ,Pathogens ,0305 other medical science ,Community-Based Intervention ,Research Article ,Adult ,Patients ,Immunology ,Antiretroviral Therapy ,Microbiology ,Peer Group ,Support group ,03 medical and health sciences ,Social support ,Antiviral Therapy ,Nursing ,Retroviruses ,Mental Health and Psychiatry ,medicine ,Humans ,Microbial Pathogens ,Health policy ,Demography ,Psychological and Psychosocial Issues ,030505 public health ,business.industry ,Lentivirus ,Ecology and Environmental Sciences ,lcsh:R ,Organisms ,Biology and Life Sciences ,HIV ,Social Support ,Peer group ,Health Care ,People and Places ,lcsh:Q ,Human medicine ,Preventive Medicine ,business ,Program Evaluation - Abstract
Reviews of impact evaluations of community-based health workers and peer support groups highlight the considerable variability in the effectiveness of such support in improving antiretroviral treatment (ART) outcomes. Evidence indicates that community-based support interventions targeting patients known to be at risk will probably display better results than generic interventions aimed at the entire population of people living with HIV. It is however difficult to identify these at-risk populations, rendering knowledge on the characteristics of patients groups who are in need of community-based support a clear research priority. The current study aims to address the knowledge gap by exploring the predictors of the willingness to (1) receive the support from a community-based health worker or (2) to participate in a support group in public sector ART programme of the Free State Province of South Africa. Based on the Individual-Family-Community framework for HIV research, the study employs a comprehensive approach by not only testing classical individual-level but also family-level predictors of the willingness to receive community-based support. In addition to individual-level predictorssuch as age, health status and coping stylesour analysis demonstrated the importance of family characteristics. The results indicated that discrepancies in the familys changeability level were an important predictor of the demand for community-based support services. Conversely, the findings indicated that patients living in a family more flexible than deemed ideal are more likely to require the support of a community health worker. The current study expands theory by indicating the need to acknowledge all social ecological levels in the study of chronic HIV care. The detection of both individual level and family level determinants of the expressed need for community-based support can inform health policy to devise strategies to target scarce resources to those vulnerable patients who report the greatest need for this support. In this way, the study results are a first step in an attempt to move away from generic, broad based community-based interventions towards community support that is tailored to the patient needs at both the individual and family level.
- Published
- 2016
9. HIV/AIDS Competent Households: Interaction between a Health-Enabling Environment and Community-Based Treatment Adherence Support for People Living with HIV/AIDS in South Africa
- Author
-
Dimitri Mortelmans, Caroline Masquillier, Harry Hausler, Wim Van Damme, Edwin Wouters, Brian van Wyk, Frailty in Ageing, and Gerontology
- Subjects
RNA viruses ,Male ,Research Facilities ,Psychological intervention ,lcsh:Medicine ,Social Sciences ,Pathology and Laboratory Medicine ,Community Networks ,Grounded theory ,South Africa ,0302 clinical medicine ,Immunodeficiency Viruses ,Sociology ,Medicine and Health Sciences ,Public and Occupational Health ,030212 general & internal medicine ,lcsh:Science ,Medicine(all) ,Family Characteristics ,Social Research ,Multidisciplinary ,Health services research ,Health Education and Awareness ,Medical Microbiology ,Viral Pathogens ,Viruses ,Female ,Health Services Research ,Pathogens ,0305 other medical science ,Engineering sciences. Technology ,Environmental Health ,Community-Based Intervention ,Research Article ,Patients ,Research and Analysis Methods ,Social issues ,Microbiology ,Medication Adherence ,03 medical and health sciences ,Acquired immunodeficiency syndrome (AIDS) ,Nursing ,Retroviruses ,medicine ,Humans ,Microbial Pathogens ,Competence (human resources) ,Acquired Immunodeficiency Syndrome ,030505 public health ,business.industry ,lcsh:R ,Lentivirus ,Organisms ,Biology and Life Sciences ,HIV ,Social environment ,medicine.disease ,Focus group ,Health Care ,lcsh:Q ,Human medicine ,business - Abstract
In the context of severe human resource shortages in HIV care, task-shifting and especially community-based support are increasingly being cited as potential means of providing durable care to chronic HIV patients. Socio-ecological theory clearly stipulates thatin all social interventionsthe interrelatedness and interdependency between individuals and their immediate social contexts should be taken into account. People living with HIV/AIDS (PLWHA) seldom live in isolation, yet community-based interventions for supporting chronic HIV patients have largely ignored the social contexts in which they are implemented. Research is thus required to investigate such community-based support within its context. The aim of this study is to address this research gap by examining the way in which HIV/AIDS competence in the household hampers or facilitates community-based treatment adherence support. The data was analyzed carefully in accordance with the Grounded Theory procedures, using Nvivo 10. More specifically, we analyzed field notes from participatory observations conducted during 48 community-based treatment adherence support sessions in townships on the outskirts of Cape Town, transcripts of 32 audio-recorded in-depth interviews with PLWHA and transcripts of 4 focus group discussions with 36 community health workers (CHWs). Despite the fact that the CHWs try to present themselves as not being openly associated with HIV/AIDS services, results show that the presence of a CHW is often seen as a marker of the disease. Depending on the HIV/AIDS competence in the household, this association can challenge the patients hybrid identity management and his/her attempt to regulate the interference of the household in the disease management. The results deepen our understanding of how the degree of HIV/AIDS competence present in a PLWHAs household affects the manner in which the CHW can perform his or her job and the associated benefits for the patient and his/her household members. In this respect, a household with a high level of HIV/AIDS competence will be more receptive to treatment adherence support, as the patient is more likely to allow interaction between the CHW and the household. In contrast, in a household which exhibits limited characteristics of HIV/AIDS competence, interaction with the treatment adherence supporter may be difficult in the beginning. In such a situation, visits from the CHW threaten the hybrid identity management. If the CHW handles this situation cautiously and the patientacting as a gate keeperallows interaction, the CHW may be able to help the household develop towards HIV/AIDS competence. This would have a more added value compared to a household which was more HIV/AIDS competent from the outset. This study indicates that pre-existing dynamics in a patients social environment, such as the HIV/AIDS competence of the household, should be taken into account when designing community-based treatment adherence programs in order to provide long-term quality care, treatment and support in the context of human resource shortages.
- Published
- 2016
10. Measuring Health-Related Quality of Life of HIV-Positive Adolescents in Resource-Constrained Settings
- Author
-
Edwin Wouters, Jasna Loos, Caroline Masquillier, and Christiana Nöstlinger
- Subjects
Male ,Gerontology ,Non-Clinical Medicine ,Culture ,Human immunodeficiency virus (HIV) ,Social and Behavioral Sciences ,medicine.disease_cause ,Pediatrics ,Sociology ,Quality of life ,Surveys and Questionnaires ,HIV Seropositivity ,Uganda ,Reliability (statistics) ,Language ,education.field_of_study ,Multidisciplinary ,Child and Adolescent Health Policy ,Confirmatory factor analysis ,Health ,HIV epidemiology ,Scale (social sciences) ,Health Resources ,Infectious diseases ,Medicine ,Female ,Research Article ,Adolescent ,Science ,Population ,Viral diseases ,Cross Culture (Sociology) ,Structural equation modeling ,Young Adult ,Adolescent Medicine ,medicine ,Humans ,education ,Biology ,Health related quality of life ,Health Care Policy ,business.industry ,HIV ,Translating ,Kenya ,Quality of Life ,Human medicine ,business - Abstract
Background and objectivesAccess to antiretroviral treatment among adolescents living with HIV (ALH) is increasing. Health-related quality of life (HRQOL) is relevant for monitoring the impact of the disease on both well-being and treatment outcomes. However, adequate screening tools to assess HRQOL in low-resource settings are scarce. This study aims to fill this research gap, by 1) assessing the psychometric properties and reliability of an Eastern African English version of a European HRQOL scale for adolescents (KIDSCREEN) and 2) determining which version of the KIDSCREEN (52-, 27- and 10-item version) is most suitable for low-resource settings.MethodsThe KIDSCREEN was translated into Eastern African English, Luganda (Uganda) and Dholuo (Kenya) according to standard procedures. The reconciled version was administered in 2011 to ALH aged 13-17 in Kenya (n = 283) and Uganda (n = 299). All three KIDSCREEN versions were fitted to the data with confirmatory factor analysis (CFA). After comparison, the most suitable version was adapted based on the CFA outcomes utilizing the results of previous formative research. In order to develop a general HRQOL factor, a second-order measurement model was fitted to the data.ResultsThe CFA results showed that without adjustments, the KIDSCREEN cannot be used for measuring the HRQOL of HIV-positive adolescents. After comparison, the most suitable version for low-resource settings--the 27-item version--was adapted further. The introduction of a negative wording factor was required for the Dholuo model. The Dholuo (CFI: 0.93; RMSEA: 0.039) and the Luganda model (CFI: 0.90; RMSEA: 0.052) showed a good fit. All cronbach's alphas of the factors were 0.70 or above. The alpha value of the Dholuo and Lugandan HRQOL second-order factor was respectively 0.84 and 0.87.ConclusionsThe study showed that the adapted KIDSCREEN-27 is an adequate tool for measuring HRQOL in low-resource settings with high HIV prevalence.
- Published
- 2012
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