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Your search keyword '"Hu, Zhibin"' showing total 32 results
32 results on '"Hu, Zhibin"'

2. Genetic Variation in the 3'-Untranslated Region of NBN Gene Is Associated with Gastric Cancer Risk in a Chinese Population

Author

Sun, Ping, primary, Du, Jiangbo, additional, Zhu, Xun, additional, Ren, Chuanli, additional, Xie, Lan, additional, Dai, Ningbin, additional, Gu, Yayun, additional, Yan, Caiwang, additional, Dai, Juncheng, additional, Ma, Hongxia, additional, Jiang, Yue, additional, Chen, Jiaping, additional, Hu, Zhibin, additional, Shen, Hongbing, additional, Wu, Haorong, additional, and Jin, Guangfu, additional

Published
2015
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3. Circulating Tumor Cells Enriched by the Depletion of Leukocytes with Bi-Antibodies in Non-Small Cell Lung Cancer: Potential Clinical Application

Author

Yin, Jian, primary, Wang, Yi, additional, Yin, Hanlu, additional, Chen, Wenping, additional, Jin, Guangfu, additional, Ma, Hongxia, additional, Dai, Juncheng, additional, Chen, Jiaping, additional, Jiang, Yue, additional, Wang, Hui, additional, Liu, Zhian, additional, Hu, Zhibin, additional, and Shen, Hongbing, additional

Published
2015
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4. Expression Quantitative Trait Loci for CARD8 Contributes to Risk of Two Infection-Related Cancers—Hepatocellular Carcinoma and Cervical Cancer

Author

Yin, Jian, primary, Wen, Juan, additional, Hang, Dong, additional, Han, Jing, additional, Jiang, Jie, additional, Song, Ci, additional, Liu, Yao, additional, Liu, Jibin, additional, Liu, Li, additional, Zhu, Liguo, additional, Chen, Jianguo, additional, Zhai, Xiangjun, additional, Xie, Shuanghua, additional, Hu, Zhibin, additional, Shen, Hongbing, additional, Dai, Min, additional, and Li, Ni, additional

Published
2015
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11. Genetic Variants at 10p11 Confer Risk of Tetralogy of Fallot in Chinese of Nanjing

Author

Xu, Jing, primary, Lin, Yuan, additional, Si, Linjie, additional, Jin, Guangfu, additional, Dai, Juncheng, additional, Wang, Cheng, additional, Chen, Jiaping, additional, Da, Min, additional, Hu, Yuanli, additional, Yi, Chenlong, additional, Hu, Zhibin, additional, Shen, Hongbing, additional, Mo, Xuming, additional, Chen, Yijiang, additional, and Wang, Xiaowei, additional

Published
2014
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14. Evaluation of Five Candidate Genes from GWAS for Association with Oligozoospermia in a Han Chinese Population

Author

Xu, Miaofei, primary, Qin, Yufeng, additional, Qu, Jianhua, additional, Lu, Chuncheng, additional, Wang, Ying, additional, Wu, Wei, additional, Song, Ling, additional, Wang, Shoulin, additional, Chen, Feng, additional, Shen, Hongbing, additional, Sha, Jiahao, additional, Hu, Zhibin, additional, Xia, Yankai, additional, and Wang, Xinru, additional

Published
2013
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19. A Large Scale Gene-Centric Association Study of Lung Function in Newly-Hired Female Cotton Textile Workers with Endotoxin Exposure

Author

Zhang, Ruyang, primary, Zhao, Yang, additional, Chu, Minjie, additional, Mehta, Amar, additional, Wei, Yongyue, additional, Liu, Yao, additional, Xun, Pengcheng, additional, Bai, Jianling, additional, Yu, Hao, additional, Su, Li, additional, Zhang, Hongxi, additional, Hu, Zhibin, additional, Shen, Hongbing, additional, Chen, Feng, additional, and Christiani, David C., additional

Published
2013
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20. Pathway Analysis for Genome-Wide Association Study of Lung Cancer in Han Chinese Population

Author

Zhang, Ruyang, primary, Zhao, Yang, additional, Chu, Minjie, additional, Wu, Chen, additional, Jin, Guangfu, additional, Dai, Juncheng, additional, Wang, Cheng, additional, Hu, Lingmin, additional, Gou, Jianwei, additional, Qian, Chen, additional, Bai, Jianling, additional, Wu, Tangchun, additional, Hu, Zhibin, additional, Lin, Dongxin, additional, Shen, Hongbing, additional, and Chen, Feng, additional

Published
2013
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26. The Study on Newly Developed McAb NJ001 Specific to Non-Small Cell Lung Cancer and Its Biological Characteristics

Author

Pan, Shiyang, primary, Wang, Fang, additional, Huang, Peijun, additional, Xu, Ting, additional, Zhang, Lixia, additional, Xu, Jian, additional, Li, Qing, additional, Xia, Wenying, additional, Sun, Ruihong, additional, Huang, Lei, additional, Peng, Ying, additional, Qin, Xuejun, additional, Shu, Yongqian, additional, Hu, Zhibin, additional, and Shen, Hongbing, additional

Published
2012
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30. Seroprevalence of Pandemic (H1N1) 2009 in Pregnant Women in China: An Observational Study

Author

Huo, Xiang, primary, Qi, Xian, additional, Tang, Fenyang, additional, Zu, Rongqiang, additional, Li, Liang, additional, Wu, Bin, additional, Qin, Yuanfang, additional, Ji, Hong, additional, Fu, Jianguang, additional, Wang, Shenjiao, additional, Tian, Hua, additional, Hu, Zhibin, additional, Yang, Haitao, additional, Zhou, Minghao, additional, Wang, Hua, additional, and Zhu, Fengcai, additional

Published
2011
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31. Genetic Polymorphisms in ZFHX3 Are Associated with Atrial Fibrillation in a Chinese Han Population.

Author

Liu, Yaowu, Ni, Bixian, Lin, Yuan, Chen, Xin-guang, Fang, Zhen, Zhao, Liyan, Hu, Zhibin, and Zhang, Fengxiang

Subjects
GENETIC polymorphisms, ATRIAL fibrillation, ZINC-finger proteins, HOMEOBOX proteins, TRANSCRIPTION factors, GENE expression, CHINESE people, DISEASES
Abstract

Background: The gene zinc finger homeobox 3 (ZFHX3) encodes a transcription factor with cardiac expression and its genetic variants are associated with atrial fibrillation (AF). We aimed to explore the associations between single nucleotide polymorphisms (SNPs) of ZFHX3 and the risk of AF in a Chinese Han population. Methods: We genotyped eight SNPs, including seven potentially functional SNPs and one previously reported SNP by using the middle-throughput iPLEX Sequenom MassARRAY platform. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated in logistic regression models. Results: We enrolled a total of 1,593 Chinese Han origin individuals in the study, including 597 AF patients and 996 non-AF controls. Logistic regression analyses revealed that potentially functional SNPs rs6499600 and rs16971436 were associated with a decreased risk of AF (adjusted OR  = 0.73, 95% CI: 0.63–0.86, P = 1.07×10−4; adjusted OR  = 0.74, 95% CI: 0.56–0.98, P = 0.039, respectively). In addition, rs2106261 showed a robust association with an increased risk of AF (adjusted OR  = 1.71, 95% CI: 1.46–2.00, P = 1.85×10−11). After multiple comparisons, rs16971436 conferred a borderline significant association with the risk of AF. Stratification analysis indicated that the risks of AF were statistically different among subgroups of age for rs2106261, and the effect for rs16971436 was more evident in subgroups of patients with coronary artery disease. Conclusion: In summary, our study investigated the role of genetic variants of ZFHX3 in AF and two SNPs (rs2106261, rs6499600) showed significant associations while rs16971436 conferred a borderline significant association with AF risk in Chinese Han populations. However, further large and functional studies are warranted to confirm our findings. [ABSTRACT FROM AUTHOR]

Published
2014
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32. Genetic Variations in the Flanking Regions of miR-101-2 Are Associated with Increased Risk of Breast Cancer.

Author

Chen, Jiaping, Qin, Zhenzhen, Jiang, Yue, Wang, Yanru, He, Yisha, Dai, Juncheng, Jin, Guangfu, Ma, Hongxia, Hu, Zhibin, Yin, Yongmei, and Shen, Hongbing

Subjects
HUMAN genetic variation, BREAST cancer risk factors, MICRORNA, DISEASE susceptibility, DISEASE progression, CANCER treatment, CANCER cells
Abstract

Genetic variants in human microRNA (miRNA) genes may alter mature miRNA processing and/or target selection, and likely contribute to cancer susceptibility and disease progression. Previous studies have suggested that miR-101 may play important roles in the development of cancer by regulating key tumor-associated genes. However, the role of single nucleotide polymorphisms (SNPs) of miR-101 in breast cancer susceptibility remains unclear. In this study, we genotyped 11 SNPs of the miR-101 genes (including miR-101-1 and miR-101-2) in a case-control study of 1064 breast cancer cases and 1073 cancer-free controls. The results revealed that rs462480 and rs1053872 in the flank regions of pre-miR-101-2 were significantly associated with increased risk of breast cancer (rs462480 AC/CC vs AA: adjusted OR = 1.182, 95% CI: 1.030–1.357, P = 0.017; rs1053872 CG/GG vs CC: adjusted OR = 1.179, 95% CI: 1.040–1.337, P = 0.010). However, the remaining 9 SNPs were not significantly associated with risk of breast cancer. Additionally, combined analysis of the two high-risk SNPs revealed that subjects carrying the variant genotypes of rs462480 and rs1053872 had increased risk of breast cancer in a dose-response manner (Ptrend = 0.002). Compared with individuals with “0–1” risk allele, those carrying “2–4” risk alleles had 1.29-fold risk of breast cancer. In conclusion, these findings suggested that the SNPs rs462480 and rs1053872 residing in miR-101-2 gene may have a solid impact on genetic susceptibility to breast cancer, which may improve our understanding of the potential contribution of miRNA SNPs to cancer pathogenesis. [ABSTRACT FROM AUTHOR]

Published
2014
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