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Your search keyword '"Sithithaworn, Paiboon"' showing total 14 results
Start Over Author "Sithithaworn, Paiboon" Journal plos neglected tropical diseases
14 results on '"Sithithaworn, Paiboon"'

2. Comparing the performance of urine and copro-antigen detection in evaluating Opisthorchis viverrini infection in communities with different transmission levels in Northeast Thailand

Author

Worasith, Chanika, primary, Wangboon, Chompunoot, additional, Duenngai, Kunyarat, additional, Kiatsopit, Nadda, additional, Kopolrat, Kulthida, additional, Techasen, Anchalee, additional, Sithithaworn, Jiraporn, additional, Khuntikeo, Narong, additional, Loilome, Watcharin, additional, Namwat, Nisana, additional, Yongvanit, Puangrat, additional, Carlton, Elizabeth J., additional, and Sithithaworn, Paiboon, additional

Published
2019
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4. Advances in the Diagnosis of Human Opisthorchiasis: Development of Opisthorchis viverrini Antigen Detection in Urine

Author

Worasith, Chanika, primary, Kamamia, Christine, additional, Yakovleva, Anna, additional, Duenngai, Kunyarat, additional, Wangboon, Chompunoot, additional, Sithithaworn, Jiraporn, additional, Watwiengkam, Nattaya, additional, Namwat, Nisana, additional, Techasen, Anchalee, additional, Loilome, Watcharin, additional, Yongvanit, Puangrat, additional, Loukas, Alex, additional, Sithithaworn, Paiboon, additional, and Bethony, Jeffrey M., additional

Published
2015
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5. Levels of 8-OxodG Predict Hepatobiliary Pathology in Opisthorchis viverrini Endemic Settings in Thailand

Author

Saichua, Prasert, primary, Yakovleva, Anna, additional, Kamamia, Christine, additional, Jariwala, Amar R., additional, Sithithaworn, Jiraporn, additional, Sripa, Banchob, additional, Brindley, Paul J., additional, Laha, Thewarach, additional, Mairiang, Eimorn, additional, Pairojkul, Chawalit, additional, Khuntikeo, Narong, additional, Mulvenna, Jason, additional, Sithithaworn, Paiboon, additional, and Bethony, Jeffrey M., additional

Published
2015
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6. Correction: Microproteinuria during Opisthorchis viverrini Infection: A Biomarker for Advanced Renal and Hepatobiliary Pathologies from Chronic Opisthorchiasis

Author

Saichua, Prasert, primary, Sithithaworn, Paiboon, additional, Jariwala, Amar R., additional, Diemert, David J., additional, Sithithaworn, Jiraporn, additional, Sripa, Banchob, additional, Laha, Thewarach, additional, Mairiang, Eimorn, additional, Pairojkul, Chawalit, additional, Periago, Maria Victoria, additional, Khuntikeo, Narong, additional, Mulvenna, Jason, additional, and Bethony, Jeffrey M., additional

Published
2013
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8. Microproteinuria during Opisthorchis viverrini Infection: A Biomarker for Advanced Renal and Hepatobiliary Pathologies from Chronic Opisthorchiasis

Author

Saichua, Prasert, primary, Sithithaworn, Paiboon, additional, Jariwala, Amar R., additional, Deimert, David J., additional, Sithithaworn, Jiraporn, additional, Sripa, Banchob, additional, Laha, Thewarach, additional, Mairiang, Eimorn, additional, Pairojkul, Chawalit, additional, Periago, Maria Victoria, additional, Khuntikeo, Narong, additional, Mulvenna, Jason, additional, and Bethony, Jeffrey M., additional

Published
2013
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11. Elevated Plasma IL-6 Associates with Increased Risk of Advanced Fibrosis and Cholangiocarcinoma in Individuals Infected by Opisthorchis viverrini

Author

Sripa, Banchob, primary, Thinkhamrop, Bandit, additional, Mairiang, Eimorn, additional, Laha, Thewarach, additional, Kaewkes, Sasithorn, additional, Sithithaworn, Paiboon, additional, Periago, Maria Victoria, additional, Bhudhisawasdi, Vajarabhongsa, additional, Yonglitthipagon, Ponlapat, additional, Mulvenna, Jason, additional, Brindley, Paul J., additional, Loukas, Alex, additional, and Bethony, Jeffrey M., additional

Published
2012
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13. Microproteinuria during Opisthorchis viverrini Infection: A Biomarker for Advanced Renal and Hepatobiliary Pathologies from Chronic Opisthorchiasis

Author

Saichua, Prasert, Sithithaworn, Paiboon, Jariwala, Amar R., Deimert, David J., Sithithaworn, Jiraporn, Sripa, Banchob, Laha, Thewarach, Mairiang, Eimorn, Pairojkul, Chawalit, Periago, Maria Victoria, Khuntikeo, Narong, Mulvenna, Jason, and Bethony, Jeffrey M.

Subjects
*INFECTION, *OPISTHORCHIS viverrini, *BIOMARKERS, *KIDNEY diseases, *OPISTHORCHIASIS, *CLONORCHIS sinensis
Abstract

Approximately 680 million people are at risk of infection with Opisthorchis viverrini (OV) and Clonorchis sinensis, with an estimated 10 million infected with OV in Southeast Asia alone. While opisthorchiasis is associated with hepatobiliary pathologies, such as advanced periductal fibrosis (APF) and cholangiocarcinoma (CCA), animal models of OV infection show that immune-complex glomerulonephritis is an important renal pathology that develops simultaneously with hepatobiliary pathologies. A cardinal sign of immune-complex glomerulonephritis is the urinary excretion of immunoglobulin G (IgG) (microproteinuria). In community-based studies in OV endemic areas along the Chi River in northeastern Thailand, we observed that over half of the participants had urine IgG against a crude OV antigen extract (OV antigen). We also observed that elevated levels of urine IgG to OV antigen were not associated with the intensity of OV infection, but were likely the result of immune-complex glomerulonephritis as seen in animal models of OV infection. Moreover, we observed that urine IgG to OV antigen was excreted at concentrations 21 times higher in individuals with APF and 158 times higher in individuals with CCA than controls. We also observed that elevated urine IgG to OV antigen could identify APF+ and CCA+ individuals from non-cases. Finally, individuals with urine IgG to OV antigen had a greater risk of APF as determined by Odds Ratios (OR = 6.69; 95%CI: 2.87, 15.58) and a greater risk of CCA (OR = 71.13; 95%CI: 15.13, 334.0) than individuals with no detectable level of urine IgG to OV antigen. Herein, we show for the first time the extensive burden of renal pathology in OV endemic areas and that a urine biomarker could serve to estimate risk for both renal and hepatobiliary pathologies during OV infection, i.e., serve as a “syndromic biomarker” of the advanced pathologies from opisthorchiasis. [ABSTRACT FROM AUTHOR]

Published
2013
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14. Population Genetic Structuring in Opisthorchis viverrini over Various Spatial Scales in Thailand and Lao PDR

Author

Laoprom, Nonglak, Sithithaworn, Paiboon, Andrews, Ross H., Ando, Katsuhiko, Laha, Thewarach, Klinbunga, Sirawut, Webster, Joanne P., and Petney, Trevor N.

Subjects
*POPULATION genetics, *OPISTHORCHIS viverrini, *ISOENZYMES, *MITOCHONDRIAL DNA
Abstract

Khon Kaen Province in northeast Thailand is known as a hot spot for opisthorchiasis in Southeast Asia. Preliminary allozyme and mitochondrial DNA haplotype data from within one endemic district in this Province (Ban Phai), indicated substantial genetic variability within Opisthorchis viverrini. Here, we used microsatellite DNA analyses to examine the genetic diversity and population structure of O. viverrini from four geographically close localities in Khon Kaen Province. Genotyping based on 12 microsatellite loci yielded a mean number of alleles per locus that ranged from 2.83 to 3.7 with an expected heterozygosity in Hardy–Weinberg equilibrium of 0.44–0.56. Assessment of population structure by pairwise FST analysis showed inter-population differentiation (P<0.05) which indicates population substructuring between these localities. Unique alleles were found in three of four localities with the highest number observed per locality being three. Our results highlight the existence of genetic diversity and population substructuring in O. viverrini over a small spatial scale which is similar to that found at a larger scale. This provides the basis for the investigation of the role of parasite genetic diversity and differentiation in transmission dynamics and control of O. viverrini. [ABSTRACT FROM AUTHOR]

Published
2012
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