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Start Over Author "Rahalison L" Journal planta medica
3 results on '"Rahalison L"'

2. Antifungal principles of Baccharis pedunculata.

Author

Rahalison L, Benathan M, Monod M, Frenk E, Gupta MP, Solis PN, Fuzzati N, and Hostettmann K

Subjects
Antifungal Agents isolation & purification, Cell Survival drug effects, Cells, Cultured, Coumarins isolation & purification, Coumarins pharmacology, Flavonoids isolation & purification, Flavonoids pharmacology, Fungi isolation & purification, Humans, Keratinocytes cytology, Keratinocytes drug effects, Lactones isolation & purification, Lactones pharmacology, Microbial Sensitivity Tests, Plant Leaves, Structure-Activity Relationship, Antifungal Agents pharmacology, Fungi drug effects, Plant Extracts
Abstract

Four compounds including a flavone, an acetylenic lactone, a prenylated coumarin, and a 3-methyl ether flavone were isolated from the dichloromethane leaf extract of Baccharis pedunculata (Mill.) Cabr. (Asteraceae). The latter three compounds were identified to be responsible for the antifungal activity against some human pathogenic and phytopathogenic fungi. The most active compound, lachnophyllum lactone, an acetylenic lactone, showed a very high toxicity (LD50 2 micrograms/ml) against human keratinocytes.

Published
1995
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3. Antifungal biphenyls from Monnina sylvatica.

Author

Bashir A, Hamburger M, Rahalison L, Monod M, Gupta MP, Solis P, and Hostettmann K

Subjects
Animals, Artemia drug effects, Biphenyl Compounds isolation & purification, Fungi drug effects, Antifungal Agents isolation & purification, Biphenyl Compounds pharmacology, Plants analysis
Published
1991
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