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Start Over Author "Pierre Champy" Journal planta medica
15 results on '"Pierre Champy"'

1. Unveiling the secrets of forgotten plants: Molecular networking-based phytochemical study of Geissospermum laeve (Vell.) Miers

Author

Mehdi A. Beniddir, Erwan Poupon, Charlotte Fox Alcover, Philippe Grellier, Christophe Duplais, Laurent Evanno, Alexandre Maciuk, Guillaume Bernadat, C Dejean, Jean-Christophe Jullian, AE Fox Ramos, and Pierre Champy

Subjects
Pharmacology, Complementary and alternative medicine, Geissospermum laeve, Phytochemical, Traditional medicine, Organic Chemistry, Drug Discovery, Molecular networking, Pharmaceutical Science, Molecular Medicine, Biology, Analytical Chemistry
Published
2016
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2. Annonaceous acetogenins from the fruit pulps of Annona reticulata and A. squamosa: Dereplicative studies

Author

Pierre Champy and Natacha Bonneau

Subjects
0106 biological sciences, Pharmacology, biology, Traditional medicine, Chemistry, Organic Chemistry, Pharmaceutical Science, 04 agricultural and veterinary sciences, biology.organism_classification, 040401 food science, 01 natural sciences, Analytical Chemistry, 0404 agricultural biotechnology, Complementary and alternative medicine, Drug Discovery, Molecular Medicine, Annonaceous Acetogenins, Annona, 010606 plant biology & botany
Published
2016
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3. Quantification of the neurotoxins Annonaceous acetogenins in the edible fruits of several Annona species using 1H NMR

Author

Pierre Champy, Natacha Bonneau, V Kagy, P Coulerie, and T Cynober

Subjects
Pharmacology, biology, Chemistry, Organic Chemistry, Pharmaceutical Science, biology.organism_classification, Analytical Chemistry, Complementary and alternative medicine, Drug Discovery, Proton NMR, Molecular Medicine, Organic chemistry, Annonaceous Acetogenins, Annona
Published
2016
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5. Out of fashion plants at the 'big data' Era: Illuminating the overlooked Apocynaceae alkaloids chemical space by Molecular Networking

Author

Mehdi A. Beniddir, Charlotte Fox Alcover, Afe Ramos, Erwan Poupon, Alexandre Maciuk, Laurent Evanno, Elvis Otogo N’Nang, and Pierre Champy

Subjects
Pharmacology, Engineering, Apocynaceae, biology, business.industry, Organic Chemistry, Big data, Pharmaceutical Science, biology.organism_classification, Data science, Chemical space, Analytical Chemistry, Complementary and alternative medicine, Drug Discovery, Molecular networking, Molecular Medicine, business
Published
2016
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6. A new dimeric monoterpene indole alkaloid from the stem bark of Pleiocarpa mutica Benth. (Apocynaceae)

Author

Mehdi A. Beniddir, Erwan Poupon, Karine Leblanc, Pierre Champy, Philippe Grellier, Laurent Evanno, Elvis Otogo N’Nang, and B Kumulungui

Subjects
Pharmacology, Stem bark, Indole alkaloid, Apocynaceae, biology, Chemistry, Monoterpene, Organic Chemistry, Pharmaceutical Science, biology.organism_classification, Analytical Chemistry, Pleiocarpa mutica, Complementary and alternative medicine, Drug Discovery, Botany, Molecular Medicine
Published
2016
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8. Antifungal and Anthelmintic Activities ofCleistopholis patens(Annonaceae)

Author

Christian Bories, François Roblot, Blandine Akendengué, Joseph Nzamba, Philippe M. Loiseau, and Pierre Champy

Subjects
Antifungal Agents, Magnetic Resonance Spectroscopy, food.ingredient, Annonaceae, Pharmaceutical Science, Microbial Sensitivity Tests, Pharmacognosy, Analytical Chemistry, food, Species Specificity, Drug Discovery, Botany, medicine, Animals, Agar, Anthelmintic, Medicinal plants, Candida albicans, Candida, Anthelmintics, Pharmacology, biology, Plant Extracts, Organic Chemistry, Fungi imperfecti, biology.organism_classification, Complementary and alternative medicine, visual_art, visual_art.visual_art_medium, Molecular Medicine, Bark, Rhabditoidea, medicine.drug
Abstract

Basic CH2Cl2 extract of the trunk bark of Cleistopholis patens (Annonaceae) exhibited antifungal activities against Candida albicans, C. parapsilosis, and C. glabrata using an agar well-diffusion assay method. Bioassay-guided fractionation of the extract led to the isolation of 8-hydroxysampangine. The methanolic extract displayed anthelmintic activity against Rhabditis pseudoelongata. Purification of the neutral CH2Cl2 extract yielded bornyl-p-transcoumarate and bornyl-p-cis-coumarate.

Published
2009
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9. A New Adjacent Bis-Tetrahydrofuran Annonaceous Acetogenin from the Seeds ofUvaria chamae

Author

Djibril Fall, Christophe Gleye, Reynald Hocquemiller, Alain Laurens, Pierre Champy, and Lorena Pimentel

Subjects
Ketone, Acetogenins, Stereochemistry, Molecular Conformation, Pharmaceutical Science, Chamuvarinin, Pharmacognosy, Analytical Chemistry, Lactones, chemistry.chemical_compound, 4-Butyrolactone, Cell Line, Tumor, Drug Discovery, Humans, Uvaria, Nuclear Magnetic Resonance, Biomolecular, Tetrahydrofuran, Pharmacology, chemistry.chemical_classification, Uvaria chamae, biology, Organic Chemistry, biology.organism_classification, Antineoplastic Agents, Phytogenic, Complementary and alternative medicine, chemistry, Annonaceae, Seeds, Acetogenin, Molecular Medicine, Fatty Alcohols, Desacetyluvaricin
Abstract

A novel acetogenin, joolanin ( 1), along with eight known acetogenins, squamocin ( 2), desacetyluvaricin ( 3), chamuvarinin ( 4), tripoxyrollin ( 5), diepoxyrollin ( 6), dieporeticanin-1 ( 7), dieporeticanin-2 ( 8) and dieporeticenin ( 9) were isolated from the seeds of Uvaria chamae (Annonaceae). Compound 1, the first adjacent bis-tetrahydrofuranic ring acetogenin bearing a ketone group at C-5, shows significant cytotoxicity towards the KB 3 - 1 cell line (IC (50) = 0.4 nM).

Published
2006
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10. Pyrone and unusually furanone-substituted flavones from the leaves of Hoslundia opposita

Author

Zakaria Cheikh-Ali, Marcelline Adiko, Pierre Champy, Erwan Poupon, Christian Bories, and Rim Salame

Subjects
Magnetic Resonance Spectroscopy, Stereochemistry, Trypanosoma brucei brucei, Antiprotozoal Agents, Pharmaceutical Science, Flavones, KB Cells, Analytical Chemistry, chemistry.chemical_compound, Parasitic Sensitivity Tests, Drug Discovery, Humans, Pharmacology, chemistry.chemical_classification, Lamiaceae, biology, Organic Chemistry, biology.organism_classification, Antineoplastic Agents, Phytogenic, Pyrone, Plant Leaves, Complementary and alternative medicine, chemistry, Pyrones, Molecular Medicine, Hoslundia opposita, Drug Screening Assays, Antitumor, Leishmania donovani
Abstract

Two new unusual 6-furanoflavones, hoslunfuranine ( 5 ) and 5- O -methylhoslunfuranine ( 6 ), were isolated from the leaves of Hoslundia opposita Vahl.. Four known methylpyranoflavonic analogues [hosloppin ( 1 ), hoslundin ( 2 ), 5- O -methylhoslundin ( 3 ), oppositin ( 4 )], all specific of the species, were also obtained. Their structures were established on the basis of their spectroscopic data. In vitro cytotoxic, trypanocidal, and leishmanicidal activities of compounds 1 and 3 to 6 were evaluated. Compounds 4 and 6 exhibited leishmanicidal potential in the micromolar range.

Published
2012

11. Mucuna pruriens efficacy in Parkison disease: Systematic approach of clinically observed synergy

Author

Abha Harfouche, Bruno Figadère, G Mazars, Pierre Champy, and Alexandre Maciuk

Subjects
Pharmacology, medicine.medical_specialty, Traditional medicine, biology, business.industry, Organic Chemistry, Pharmaceutical Science, Disease, biology.organism_classification, Analytical Chemistry, Surgery, Complementary and alternative medicine, Drug Discovery, medicine, Molecular Medicine, business, Mucuna pruriens
Published
2012
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12. Annonaceous acetogenins within extracts: dereplication by HPLC-ESI-LTQ-Orbitrap® using post-column lithium infusion

Author

Isabelle Schmitz-Afonso, Pierre Champy, J Le Ven, Olivier Laprévote, Alain Brunelle, David Touboul, and Guy Lewin

Subjects
Pharmacology, Chromatography, Chemistry, Organic Chemistry, Pharmaceutical Science, chemistry.chemical_element, Orbitrap, Combinatorial chemistry, High-performance liquid chromatography, Analytical Chemistry, law.invention, Complementary and alternative medicine, law, Drug Discovery, Molecular Medicine, Lithium, Annonaceous Acetogenins, Column (botany)
Published
2012
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13. Phytochemical and biological analysis of Mallotus oppositifolius (Euphorbiaceae)

Author

Karine Leblanc, Christian Bories, FA Kabran, Bruno Figadère, Alexandre Maciuk, LA Djakouré, Blandine Séon-Méniel, Pierre Champy, and T. A. Okpekon

Subjects
Pharmacology, biology, Traditional medicine, Organic Chemistry, Euphorbiaceae, Pharmaceutical Science, biology.organism_classification, Mallotus oppositifolius, Analytical Chemistry, Phytochemical, Complementary and alternative medicine, Botany, Drug Discovery, Molecular Medicine
Published
2012
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14. Atypical parkinsonism induced by Annonaceae: Where are we yet?

Author

Olivier Laprévote, I. N. Bajin, Günter U. Höglinger, Pierre Champy, Myriam Escobar-Khondiker, Merle Ruberg, Annie Lannuzel, and E. Yamada

Subjects
Pharmacology, biology, Chemistry, Stereochemistry, Organic Chemistry, Pharmaceutical Science, biology.organism_classification, Analytical Chemistry, Complementary and alternative medicine, Annonaceae, Drug Discovery, Molecular Medicine, Atypical Parkinsonism
Published
2008
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15. High-resolution bioguided screening of Ganoderma capense for P-GP modulating activity

Author

H. P. Ta, Sarah Vautier, S. Welti, Aline Milane, I. W. Wainer, Pierre Champy, Christine Fernandez, Bruno Figadère, and Alexandre Maciuk

Subjects
Pharmacology, Complementary and alternative medicine, Traditional medicine, Ganoderma capense, Chemistry, Stereochemistry, Organic Chemistry, Drug Discovery, Pharmaceutical Science, Molecular Medicine, High resolution, Analytical Chemistry
Published
2008
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