1. Oleanane-type triterpenes from the flowers, pith, leaves, and fruit of Tetrapanax papyriferus
- Author
-
Chiu-Ming Chen, Jiau-Ching Ho, and Lie-Ching Row
- Subjects
Magnetic Resonance Spectroscopy ,Stereochemistry ,Anti-HIV Agents ,Anti-Inflammatory Agents ,Taiwan ,Plant Science ,Flowers ,Horticulture ,Biochemistry ,Terpene ,chemistry.chemical_compound ,Triterpene ,Botany ,Animals ,Humans ,Lymphocytes ,Medicine, Chinese Traditional ,Oleanolic Acid ,Molecular Biology ,Oleanane ,Oleanolic acid ,chemistry.chemical_classification ,Apiaceae ,Tetrapanax ,biology ,Plant Extracts ,General Medicine ,biology.organism_classification ,Plant Leaves ,chemistry ,Seeds ,Araliaceae ,Pith ,Artemia - Abstract
Four oleanane-type triterpenes, 3alpha,21beta,22alpha-trihydroxy-11,13(18)-oleanadien-28-oic acid (1), 3-epi-papyriogenin C (2), 21-O-acetyl-21-hydroxy-3-oxo-11,13(18)-oleanadien-28-oic acid (3) and 3beta-hydroxy-21-oxo-11,13(18)-oleanadien-28-oic acid methyl ester (4), together with four known triterpenes, were isolated from Tetrapanax papyriferus (Hook) K. Koch. Papyriogenin A (8) exhibited anti-HIV activity and low cytotoxicity in acutely infected H9 lymphocytes. Their structures were determined by analysis of spectroscopic data, including by 1D and 2D NMR.
- Published
- 2005