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The main objective of this work is to comprehensively provide a fundamental understanding of the entire process of the flame-pressure wave interactions with end-gas autoignition and detonation development in a confined chamber by two-dimensional numerical simulations with a stoichiometric hydrogen/air mixture. The flame dynamics, pressure wave propagation, and its structure evolution, together with the mechanism of autoignition and detonation development in the end gas, are analyzed in detail. Six stages, including spherical flame, finger flame, flame with its skirt touching the sidewalls, flame-pressure wave interactions, end-gas autoignition induced by the flame-pressure wave interactions, and detonation development, are observed for the flame development in the confined space. The results demonstrate that the flame-pressure wave multi-interactions result in violent oscillations of the flame shape and speed. Three stages of flame shape evolution during each interaction, backward propagation of the flame front, stretch of the flame front at the boundary layer, and formation of the tulip flame, are captured. A new mechanism in terms of combined effects of the viscous boundary layer and pressure waves is provided for the formation of the tulip flame. It is also found that the velocity distributions in the boundary layer show the trend of increase first and then decrease after the pressure waves pass the fields twice in the opposite directions. The autoignition occurrence and detonation initiation at different positions and different moments in the end-gas region are analyzed. It is indicated that the nonuniform temperature distribution induced by the reflections of pressure waves and the specific pressure wave structures can be responsible for this phenomenon. [ABSTRACT FROM AUTHOR]