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Advancements in radiotherapy auto-segmentation necessitate reliable and efficient workflows. Therefore, a standardized fully automatic workflow was developed for three commercially available deep learning-based auto-segmentation applications and compared to a manual workflow for safety and efficiency. The workflow underwent safety evaluation with failure mode and effects analysis. Notably, eight failure modes were reduced, including seven with severity factors ≥7, indicating the effect on patients, and two with Risk Priority Number value >125, which assesses relative risk level. Efficiency, measured by mouse clicks, showed zero clicks with the automatic workflow. This automation illustrated improvement in both safety and efficiency of workflow.

In radiotherapy treatment planning, optimization is essential for achieving the most favorable plan by adjusting optimization criteria. This study introduced an innovative approach to automatically fine-tune optimization parameters for volumetric modulated arc therapy prostate planning, ensuring all constraints were met. A knowledge-based planning model was invoked, and the fine-tuning process was applied through an in-house developed script. Among 25 prostate plans, this fine-tuning increased the number of plans meeting all constraints from 10/25 to 22/25, with a reduction in mean monitor units per gray without increasing plan’s complexity. This automation improved efficiency by saving time and resources in treatment planning.

Background and purpose: A dosimetry audit program based on alanine electron paramagnetic resonance (EPR) and radiochromic film dosimetry, may be a valuable tool for monitoring and improving the quality of lung stereotactic body radiotherapy (SBRT). The aim of this study was to report the initial, independent assessment of the dosimetric accuracy for lung SBRT practice using these dosimeters in combination with a novel phantom design. Materials and Methods: The audit service was a remote audit program performed on a commercial lung phantom preloaded with film and alanine detectors. An alanine pellet was placed in the centre of the target simulated using silicone in a 3D-printed mould. Large film detectors were placed coronally through the target and the lung/tissue interface and analysed using gamma analysis. The beam output was always checked on the same day with alanine dosimetry in water. We audited 29 plans from 14 centres up to now. Results: For the alanine results 28/29 plans were within 5 % with 19/29 plans being within 3 %. The passing rates were > 95 % for the film through the target for 27/29 plans and 17/29 plans for the film at the lung/tissue interface. For three plans the passing rate was