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Abraham model solute descriptors are determined for vanillin and five select derivatives (o-vanillin, isovanillin, vanillic acid, vanillyl alcohol and ethylvanillin) based on experimental solubility and partition coefficient data that we were able to find in the published literature. The solute descriptor values reported in the current communication back-calculate the observed experimental data to within standard errors of 0.12 log units (or less). The calculated solute descriptors can be used to predict the solubility of the vanillin and the five select derivatives in additional organic mono-solvents and binary aqueous-ethanol solvent mixtures using published Abraham model correlations. [ABSTRACT FROM AUTHOR]

Published experimental solubility data reported in the chemical literature for maltol dissolved in 13 organic mono-solvents are used to calculate solute descriptors based on the Abraham solvation parameter model. The solute descriptors once calculated are used to predict both the solubility of maltol in additional organic mono-solvents and the water-to-organic solvent partition coefficients. [ABSTRACT FROM AUTHOR]

Experimental solubilities have been measured for isophthalic acid dissolved in eleven primary alcohol, three secondary alcohol and three alkoxyalcohol solvents at 298 K. Results of the experimental measurements, combined with published solubility data for isophthalic acid in ethyl acetate, acetic acid, acetophenone, acetone, cyclohexanone, propyl acetate, N-methyl-2-pyrrolidone and tetrahydrofuran, were used to determine the Abraham model solute descriptors for isophthalic acid. The calculated solute descriptors described the measured solubility data to within an overall average standard deviation of 0.15 log units. [ABSTRACT FROM AUTHOR]

Mole fraction solubilities are reported for 1,4-dichloro-2-nitrobenzene dissolved in 24 organic solvents of varying polarity and hydrogen-bonding character. The experimental data are used to calculate Abraham solute descriptors. The calculated solute descriptors describe the experimental data to within an overall average standard deviation of 0.081 log units. Also reported in the manuscript are Abraham model solute descriptors for both 3,4-dichloro-1-nitrobenzene and 2,3-dichloro-1-nitrobenzene based on published literature data. [ABSTRACT FROM AUTHOR]