Search

Your search keyword '"Khaligh, Aisan"' showing total 3 results
Start Over Author "Khaligh, Aisan" Journal photochemical & photobiological sciences
3 results on '"Khaligh, Aisan"'

2. Water-dispersible glycosylated poly(2,5′-thienylene)porphyrin-based nanoparticles for antibacterial photodynamic therapy.

Author

Khan, Rehan, Özkan, Melis, Khaligh, Aisan, and Tuncel, Dönüs

Subjects
PHOTODYNAMIC therapy, GRAM-negative bacteria, NANOPARTICLES, REACTIVE oxygen species, BACILLUS subtilis, GLYCOSYLATED hemoglobin
Abstract

Here we report the preparation of water-dispersible glycosylated poly(2,5′-thienylene)porphyrin based nanoparticles by a nanoprecipitation method and demonstrate the application of these nanoparticles in antibacterial photodynamic therapy. The diameter of the nanoparticles is in the range of 50–80 nm and the resulting nanoparticles are stable in water without precipitation at least for a month. They have high singlet oxygen efficiency and display light-triggered biocidal activity against both Gram negative bacteria (Escherichia coli, E. coli) and Gram positive bacteria (Bacillus subtilis, B. subtilis). Upon white light irradiation for 10 min with a flux of 22 mW cm−2 of the E. coli suspension incubated with NPs (18 μg mL−1), a killing efficiency of 99% is achieved, whereas in the dark the effect is recorded as only around 8%. [ABSTRACT FROM AUTHOR]

Published
2019
Full Text
View/download PDF

3. Water-dispersible glycosylated poly (2,5’-thienylene)porphyrin-based nanoparticles for antibacterial photodynamic therapy

Author

Dönüs Tuncel, Melis Özkan, Aisan Khaligh, Rehan Khan, Khan, Rehan, Özkan, Melis, Khaligh, Aisan, and Tuncel, Dönüş

Subjects
Glycosylation, Porphyrins, Gram-negative bacteria, Polymers, medicine.medical_treatment, Gram-positive bacteria, Nanoparticle, Photodynamic therapy, Microbial Sensitivity Tests, Bacillus subtilis, 010402 general chemistry, medicine.disease_cause, 01 natural sciences, chemistry.chemical_compound, Escherichia coli, medicine, Physical and Theoretical Chemistry, Photosensitizing Agents, Molecular Structure, biology, 010405 organic chemistry, Singlet oxygen, Water, biology.organism_classification, Porphyrin, 6. Clean water, Anti-Bacterial Agents, 0104 chemical sciences, Photochemotherapy, chemistry, Nanoparticles, Nuclear chemistry
Abstract

Here we report the preparation of water-dispersible glycosylated poly(2,5'-thienylene) porphyrin based nanoparticles by a nanoprecipitation method and demonstrate the application of these nanoparticles in antibacterial photodynamic therapy. The diameter of the nanoparticles is in the range of 50-80 nm and the resulting nanoparticles are stable in water without precipitation at least for a month. They have high singlet oxygen efficiency and display light-triggered biocidal activity against both Gram negative bacteria (Escherichia coli, E. coli) and Gram positive bacteria (Bacillus subtilis, B. subtilis). Upon white light irradiation for 10 min with a flux of 22 mW cm(-2) of the E. coli suspension incubated with NPs (18 mu g mL(-1)), a killing efficiency of 99% is achieved, whereas in the dark the effect is recorded as only around 8%.

Published
2019

Catalog

Books, media, physical & digital resources
See catalog results