12 results on '"Rabe, E"'
Search Results
2. Guidelines of the First International Consensus Conference on Endovenous Thermal Ablation for Varicose Vein Disease--ETAV Consensus Meeting 2012.
- Author
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Pavlović MD, Schuller-Petrović S, Pichot O, Rabe E, Maurins U, Morrison N, and Pannier F
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- Anesthesia methods, Catheter Ablation adverse effects, Collagen ultrastructure, Contraindications, Endovascular Procedures adverse effects, Fibrosis, Hot Temperature, Humans, Informed Consent, Laser Therapy adverse effects, Outcome Assessment, Health Care standards, Physical Examination, Postoperative Complications prevention & control, Preoperative Care, Protein Denaturation, Solutions administration & dosage, Steam, Ultrasonography, Interventional, Varicose Veins diagnostic imaging, Varicose Veins pathology, Varicose Veins surgery, Vascular Patency, Catheter Ablation methods, Endovascular Procedures methods, Laser Therapy methods, Varicose Veins therapy
- Abstract
Aim: Endovenous thermal ablation (ETA) procedures are catheter-directed, ultrasound (US)-guided thermal methods for treatment in varicose veins disease. Radiofrequency, laser or steam energy thermally denatures vein wall collagen, leading first to vein wall inflammation, then fibrosis and finally to occlusion. The aim of this guideline is to give evidence-based recommendations for ETA procedures., Methods: These guidelines were drafted during a consensus meeting of a group of experts in the field of ETA in June 2012 (Hvar, Croatia) under the auspices of the International Union of Phlebology (IUP). These guidelines review the present state of knowledge as reflected in peer-reviewed published medical literature. The recommendations of these guidelines are graded according to the American College of Chest Physicians Task Force recommendations on Grading Strength of Recommendations and Quality of Evidence in Clinical Guidelines., Results: Recommendations on the use of ETA procedures were made based on the quality of evidence for efficacy, safety, tolerability, cosmetic outcome, patient satisfaction/preference and, where appropriate, on the experts' opinion. Health economics were not considered, since differences in national health systems and pricing make it difficult to form general conclusions that are relevant at an international level., (© The Author(s) 2014 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.)
- Published
- 2015
- Full Text
- View/download PDF
3. Embolization is not essential in the treatment of leg varices due to pelvic venous insufficiency.
- Author
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Rabe E and Pannier F
- Subjects
- Female, Humans, Leg pathology, Pelvis pathology, Varicose Veins pathology, Varicose Veins physiopathology, Venous Insufficiency pathology, Venous Insufficiency physiopathology, Embolization, Therapeutic, Leg blood supply, Pelvis blood supply, Varicose Veins therapy, Venous Insufficiency therapy
- Abstract
Aim: To consider if it is essential to perform embolization in the treatment of leg varices due to pelvic venous insufficiency., Methods: Review of the current literature concerning treatment options of leg varicose veins of pelvic origin., Results: Pelvic venous insufficiency, vulvar and pudendal varicose veins as well as pelvic congestive syndrome are under diagnosed entities. Embolization of ovarian and pelvic veins is well established in patients with pelvic congestive syndrome. In varicose veins of pelvic origin but without pelvic congestive syndrome, comparative studies comparing the outcome of embolization or treatment of varicose veins by sclerotherapy or phlebectomy alone are missing. Foam sclerotherapy or phlebectomy shows good results in patients with varicose veins of pelvic origin., Conclusions: Embolization is not essential in the treatment of leg varices of pelvic origin without pelvic congestive syndrome. Foam sclerotherapy or phlebectomy shows good results in patients with vulvar or pudendal varicose veins. Randomized comparative studies using embolization of incompetent pelvic veins or sclerotherapy of varicose veins with pelvic origin should be performed., (© The Author(s) 2015 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.)
- Published
- 2015
- Full Text
- View/download PDF
4. European guidelines for sclerotherapy in chronic venous disorders.
- Author
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Rabe E, Breu FX, Cavezzi A, Coleridge Smith P, Frullini A, Gillet JL, Guex JJ, Hamel-Desnos C, Kern P, Partsch B, Ramelet AA, Tessari L, and Pannier F
- Subjects
- Chronic Disease, Europe, Female, Humans, Male, Polidocanol, Polyethylene Glycols adverse effects, Sclerosing Solutions adverse effects, Sclerotherapy methods, Societies, Medical, Polyethylene Glycols therapeutic use, Sclerosing Solutions therapeutic use, Sclerotherapy standards, Sodium Tetradecyl Sulfate therapeutic use, Varicose Veins therapy
- Abstract
Aim: Sclerotherapy is the targeted chemical ablation of varicose veins by intravenous injection of a liquid or foamed sclerosing drug. The treated veins may be intradermal, subcutaneous, and/or transfascial as well as superficial and deep in venous malformations. The aim of this guideline is to give evidence-based recommendations for liquid and foam sclerotherapy., Methods: This guideline was drafted on behalf of 23 European Phlebological Societies during a Guideline Conference on 7-10 May 2012 in Mainz. The conference was organized by the German Society of Phlebology. These guidelines review the present state of knowledge as reflected in published medical literature. The regulatory situation of sclerosant drugs differs from country to country but this has not been considered in this document. The recommendations of this guideline are graded according to the American College of Chest Physicians Task Force recommendations on Grading Strength of Recommendations and Quality of Evidence in Clinical Guidelines., Results: This guideline focuses on the two sclerosing drugs which are licensed in the majority of the European countries, polidocanol and sodium tetradecyl sulphate. Other sclerosants are not discussed in detail. The guideline gives recommendations concerning indications, contraindications, side-effects, concentrations, volumes, technique and efficacy of liquid and foam sclerotherapy of varicose veins and venous malformations., (© The Author(s) 2013 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.)
- Published
- 2014
- Full Text
- View/download PDF
5. Manuscripts from the European venous course.
- Author
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Wittens CH, Bækgaard N, Smith PC, Rabe E, Pittaluga P, and Labropoulos N
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- Cooperative Behavior, Diffusion of Innovation, Humans, International Cooperation, Societies, Medical, Varicose Veins diagnosis, Varicose Veins therapy, Venous Insufficiency diagnosis, Venous Insufficiency therapy
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- 2013
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6. The relevance of the natural history of varicose veins and refunded care.
- Author
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Pannier F and Rabe E
- Subjects
- Chronic Disease, Humans, Varicose Veins pathology, Varicose Veins therapy, Venous Insufficiency pathology, Venous Insufficiency therapy, Disease Progression, Quality of Life, Varicose Veins complications, Varicose Veins physiopathology, Venous Insufficiency etiology, Venous Insufficiency physiopathology
- Abstract
Chronic venous disease (CVD) is one of the most common diseases in our population. Aside from venous symptoms like heaviness and pain, which are present in about 50% of the general population, signs of CVD include varicose veins (VVs), oedema, eczema, venous eczema, hyperpigmentation, white atrophy, lipodermatosclerosis and venous ulcers. The aim of this paper is to review current literature for the relevance of natural history of VVs in refunded care. Available papers on VVs, progression of the disease and complications were reviewed. Prevalence of VVs is high with more than 20% in the general population. Information on progression of uncomplicated VV to chronic venous insufficiency (CVI) is rare. However, most venous ulcers have a primary venous origin. The progression rate of VV to higher clinical stages reaches 4% per year. Among the risk factors are obesity and higher age. Quality of life (QOL) is also reduced in uncomplicated VV in C2 patients. In conclusion, there is evidence from the literature that a high proportion of patients with uncomplicated VVs in the clinical, aetiological, anatomical and pathophysiological classification (CEAP Clinical Class 2) will progress to CVI if untreated. VVs have a negative impact on QOL and clinical symptoms. VV patients with CVI (C3-C6) as well as those C2 patients with severe clinical symptoms and impaired QOL due to CVD should be treated with ablation of the VVs in a refunded care system.
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- 2012
- Full Text
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7. Clinical, aetiological, anatomical and pathological classification (CEAP): gold standard and limits.
- Author
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Rabe E and Pannier F
- Subjects
- Chronic Disease, Congresses as Topic, Hawaii, Humans, Classification, Varicose Veins classification, Varicose Veins etiology, Varicose Veins pathology
- Abstract
The first CEAP (clinical, aetiological, anatomical and pathological elements) consensus document was published after a consensus conference of the American Venous Forum, held at the sixth annual meeting of the AVF in February 1994 in Maui, Hawaii. In the following years the CEAP classification was published in many international journals and books which has led to widespread international use of the CEAP classification since 1995. The aim of this paper is to review the benefits and limits of CEAP from the available literature. In an actual Medline analysis with the keywords 'CEAP' and 'venous insufficiency', 266 publications using the CEAP classification in venous diseases are available. The CEAP classification was accepted in the venous community and used in scientific publications, but in most of the cases only the clinical classification was used. Limitations of the first version including a lack of clear definition of clinical signs led to a revised version. The CEAP classification is the gold standard of classification of chronic venous disorders today. Nevertheless for proper use some facts have to be taken into account: the CEAP classification is not a severity classification, C2 summarizes all kinds of varicose veins, in C3 it may be difficult to separate venous and other reasons for oedema, and corona phlebectatica is not included in the classification. Further revisions of the CEAP classification may help to overcome the still-existing deficits.
- Published
- 2012
- Full Text
- View/download PDF
8. Changes in venous function after foam sclerotherapy of varicose veins.
- Author
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Brunken A, Rabe E, and Pannier F
- Subjects
- Aged, Female, Hemodynamics, Humans, Male, Middle Aged, Plethysmography methods, Polidocanol, Polyethylene Glycols administration & dosage, Prospective Studies, Treatment Outcome, Veins physiology, Veins physiopathology, Sclerosing Solutions administration & dosage, Sclerotherapy methods, Varicose Veins therapy
- Abstract
Objectives: Foam sclerotherapy of varicose veins has recently proven to be an effective, economic and safe treatment modality. The present study attempts to evaluate the haemodynamic changes after sclerotherapy in addition to the clinical results., Methods: In a prospective observation trial, 67 sites (2/3 of which were recurrent varicose [RV] veins after previous treatment) in 53 patients were treated with polidocanol foam, and the results were assessed clinically, by duplex, photoplethysmography and strain gauge plethysmography., Results: With the exception of two sites (3.0%), all treatments resulted at least in an improvement, and about 80% of the treated veins were completely occluded as demonstrated by duplex ultrasound examination. The haemodynamical results accordingly reflected a significant improvement of the venous function. Patients with post-thrombotic syndrome showed poorer results., Conclusion: Foam sclerotherapy is a highly effective and safe method for the treatment of primary and RV veins.
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- 2009
- Full Text
- View/download PDF
9. Indications, contraindications and performance: European Guidelines for Sclerotherapy in Chronic Venous Disorders*.
- Author
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Rabe, E and Pannier, F
- Subjects
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SCLEROTHERAPY , *VARICOSE veins , *CONFERENCES & conventions , *VASCULAR diseases , *INJECTIONS , *MEDICAL protocols , *SULFUR acids , *DRUG administration , *DRUG dosage , *THERAPEUTICS ,TREATMENT of vascular diseases - Abstract
Aim: Sclerotherapy is the targeted chemical ablation of varicose veins by intravenous injection of a liquid or foamed sclerosing drug. The treated veins may be intradermal, subcutaneous, and/or transfascial as well as superficial and deep in venous malformations. The aim of this guideline is to give evidence-based recommendations for liquid and foam sclerotherapy. Methods: This guideline was drafted on behalf of 23 European Phlebological Societies during a Guideline Conference on 7th–10th May 2012 in Mainz. The conference was organized by the German Society of Phlebology. Results: This guideline focuses on the two sclerosing drugs which are licensed in the majority of the European countries, Polidocanol (POL) and Sodium tetradecyl sulphate (STS). Other sclerosants are not discussed in detail. In this paper the recommendations concerning indications, contraindications, concentrations, volumes and technique of liquid and foam sclerotherapy of varicose veins and venous malformations are reviewed. [ABSTRACT FROM AUTHOR]
- Published
- 2014
- Full Text
- View/download PDF
10. Results from RCTs in Sclerotherapy: European Guidelines for Sclerotherapy in Chronic Venous Disorders*.
- Author
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Pannier, F and Rabe, E
- Subjects
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SCLEROTHERAPY , *VARICOSE veins , *VASCULAR diseases , *CLINICAL medicine , *EVALUATION of medical care , *MEDICAL protocols , *HEALTH outcome assessment , *THERAPEUTICS ,TREATMENT of vascular diseases - Abstract
Aim: Sclerotherapy is the targeted chemical ablation of varicose veins by intravenous injection of a liquid or foamed sclerosing drug. The treated veins may be intradermal, subcutaneous, and/or transfascial as well as superficial and deep in venous malformations. The aim of this guideline is to give evidence-based recommendations for liquid and foam sclerotherapy. Methods: This guideline was drafted on behalf of 23 European Phlebological Societies during a Guideline Conference on 7th–10th May 2012 in Mainz. The conference was organized by the German Society of Phlebology. Results: This guideline focuses on the two sclerosing drugs which are licensed in the majority of the European countries, Polidocanol (POL) and Sodium tetradecyl sulphate (STS). Other sclerosants are not discussed in detail. In this paper the results from recent RCTs in sclerotherapy are reviewed. [ABSTRACT FROM AUTHOR]
- Published
- 2014
- Full Text
- View/download PDF
11. Endovenous laser ablation of great saphenous veins using a 1470 nm diode laser and the radial fibre - follow-up after six months.
- Author
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Pannier, F., Rabe, E., Rits, J., Kadiss, A., and Maurins, U.
- Subjects
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VARICOSE veins , *ANALYSIS of variance , *COMPRESSION stockings , *MEDICAL lasers , *LONGITUDINAL method , *HEALTH outcome assessment , *POSTOPERATIVE pain , *SAPHENOUS vein , *TREATMENT effectiveness , *DATA analysis software , *THERAPEUTICS - Abstract
Background: Endovenous laser ablation (EVLA) is an efficient method to treat insufficient great saphenous veins (GSV) with high occlusion rates. Most studies used 810, 940 or 980 nm diode lasers and a bare fibre. Moderate postoperative pain and bruising are frequent findings. Laser systems with higher wavelengths like 1470 nm with a higher absorption in water show less pain and bruising after the procedure. A newly developed fibre (radial fibre, Biolitec) emits the laser energy radially around the tip directly into the venous wall contrary to the bare fibre. The aim of this study was to demonstrate the outcome and side-effects after EVLA of GSV with a 1470 nm diode laser (Ceralas E, Biolitec) by using the radial fibre. Methods: Non-randomized, prospective study including 50 unselected limbs of 50 patients with a duplex sonographically verified incompetent GSV. EVLA was performed with a 1470 nm diode laser (Ceralas E, Biolitec) and a radial fibre. In the same session all insufficient tributaries were treated by phlebectomy. Tumescent local anaesthesia with 0.05% lidocaine was applied perivenously. Laser treatment was carried out in a continuous mode with a power of 15W. Compression stockings (30 mmHg) were applied for one month. Postinterventional checkups took place one, 10, 30 days and six months after the procedure. Results: Three patients were lost to follow-up. The average linear endovenous energy density (LEED) was 90.8 J/cm vein (SD 35.3). At the six month follow-up all treated veins remained occluded and no new reflux in the treated segments occurred. No recurrent varicose veins had occurred so far. No severe complications such as deep venous thrombosis could be detected. In four patients at 30 days and three patients at six months local paresthesia occurred in the region of EVLA. Forty-four percent of patients did not have any pain after the treatment and 50% did not take any analgesic tablets at any time after the procedure. Postoperative ecchymoses in the track of the treated GSV was rare. In 80% of the limbs, no ecchymoses was observed after the treatment. Conclusion: EVLA of GSV with a radially emitting laser fibre by using a 1470 nmdiode laser is a safe and efficient treatment option. [ABSTRACT FROM AUTHOR]
- Published
- 2011
- Full Text
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12. Progression in venous pathology.
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Pannier, F and Rabe, E
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VASCULAR diseases , *LONGITUDINAL method , *MEDLINE , *ONLINE information services , *SKIN abnormalities , *VARICOSE veins , *VENOUS insufficiency , *LITERATURE reviews , *BODY mass index , *DISEASE prevalence , *CASE-control method , *DISEASE progression , *EARLY medical intervention , *SURGERY , *ULCERS , *DISEASE risk factors ,LEG ulcers - Abstract
The article presents a review of epidemiologic studies concerning the progression of venous pathology in varicose veins and from varicose veins towards chronic venous insufficiency. Data from Medline and PubMed indicate that reflux progression may develop from segmental to multisegmental superficial reflux. Risk factors for the progression of varicose veins towards venous leg ulcers include skin changes, corona phlebectatica and popliteal vein reflux.
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- 2015
- Full Text
- View/download PDF
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