Search

Your search keyword '"Yitian Wu"' showing total 2 results
Start Over Author "Yitian Wu" Journal pharmaceuticals (basel, switzerland)
2 results on '"Yitian Wu"'

1. Optimized Therapeutic

Author

Yitian, Wu, Xiaojun, Zhang, Xiaojiang, Duan, Xing, Yang, Feng, Wang, and Jinming, Zhang

Abstract

Clinical trials have shown the significant efficacy of [

Published
2022

2. Optimized

Author

Yitian, Wu, Xiaojun, Zhang, Ying, Zhang, Baixuan, Xu, Jiahe, Tian, and Jinming, Zhang

Abstract

Prostate-specific membrane antigen (PSMA)-targeting radiopharmaceuticals have become some of the most promising tools for the diagnosis and therapy prostate cancer (PCa). The structure of existing PSMA-targeted PET tracers still needs to be optimized to improve their pharmacokinetic properties and tumor-to-background ratio. In this study, we modified the structure of a well-studied PSMA tracer, and six novel tracers with variable hydrophilicity and pharmacokinetics were developed and evaluated both in vitro and in vivo. All of the novel tracers showed high hydrophilicity (log

Published
2022

Catalog

Books, media, physical & digital resources
See catalog results