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One among Fabaceae member Flemingia strobilifera W.Ation is a very useful herbal drug. Leaf of the same is collected, authentified and used for the study. Morphological study of leaf reveals it as a simple leaf with slightly wavy margin, ovate-lanceolate shape with pulvinous petiole. Leaf microscopy shows blacklids, simple trichome with tannin content. Bundle sheath cells are mostly filled with Calcium oxalate crystal. Ground tissue made up of parenchyma cells heavily deposited by rhomboidal crystal of calcium oxalate, tannin content, simple and compound starch grains and oil globules. Epidermis is covered by cuticle. Lower and upper epidermis is having Trichome. Lower epidermis interrupted by stomata. Mesophyll tissue is rich in oil globules and crystals. Powder microscopy of leaf shows simple unicellular trichome, oil globule, dark brown tannin content, rhomboidal crystal and fragment of paracitic stomata. Physicochemical analysis revealed presence of carbohydrates, saponins, glycosides, steroids and flavonoid. HPTLC study of alkaloid showed the presence of four and two spots in short and long UV respectively. These characteristics will be helpful to identify the plant Flemingia strobilifera. [ABSTRACT FROM AUTHOR]

In Ayurveda classics Nitya sevaniya (wholesome daily food) and Nitya asevaniya (unwholesome daily food) have described in detail. Present study aims at differentiation of characters of some of Nityasevaniya (Mudga, Raktashali, Godhuma) and asevaniya (Masha) aharadravya on the basis of pharmaceutical analysis. Loss on drying was found highest in Masha i.e. 11.65% and lowest in Mudga i.e. 7.6.Ash value of Masha found lowest i.e. 1.8 while Ash value of Raktashali found highest i.e. 21.85. water solubility was found maximum in Mudga i.e. 13.9 while minimum in Masha i.e. 6.5.Mudga, Raktashali and Godhumahave pH as 4 while Masha have pH as 5. Proteins were found maximum in old Mudga i.e. 25.45 g/100g while carbohydrates were found maximum in Raktashali i.e. 74.32 g/100g. All these parameters proves dominance of Prithvi and Jala Mahabhuta in Masha and Vayu-Akasha Mahabhuta in other selected food items. [ABSTRACT FROM AUTHOR]

Cassia mimosoides L. sub family Caesalpiniaceae is locally known as Aaval ni Jaat in Gujarati. Ethno medicinal reports, includes the use of root for diarrhea and stomach spasm, pulverized leaf paste was applied for wound healing and seed were used as tonic. It is an unexplored plant hence the present study reports the result of Physico-Phytochemical analysis and Rasanirdharana. The perceived Rasa is found Kashaya, Madhura and Tikta rasa and the physicochemical analysis reveals that the Loss on drying of the sample is 7.044% w/w and preliminary qualitative analysis shows presence of Carbohydrates, cardiac glycosides, flavonoids, steroid and tannin content in methanolic extract. The HPTLC result gives the 4 peaks at 254 nm and 3 peaks at 366 nm. The observed data could be helpful to identify the plant Cassia mimosoides L. at Physico-Phytochemical level. [ABSTRACT FROM AUTHOR]

Panchkola Churna is a compound Ayurvedic formulation prescribed in the management of indigestion. Pharmacognostical study counting powder microscopy of raw drug exposed the quality and genuineness of all the constituents of Panchkola Churna. Organoleptic features of coarse powder made out of the crude drugs were within the standard range. Loss on drying was 8.86%w/w and pH was 3.5. Total ash of powder was7.096% w/w, and acid insoluble ash was 0.799% w/w. High Performance Thin Layer Chromatography (HPTLC) showed 9 spots at 254 and 6 spots at 366 nm. This shows the presence of certain definite constituents in the Churna and is helpful for the easy separation of these constituents. [ABSTRACT FROM AUTHOR]

Paracetamol (PCM) is widely used as analgesic and antipyretic drug, but at high doses it leads to undesirable side effects, such as hepatotoxicity. The present study evaluates the hepatoprotective activity of Vasaguduchyadi Kwatha (an herbal formulation content of 08 drugs) against paracetamol induced toxicity. Honey used as vehicle and Silymarin as a reference standard. Paracetamol induced hepatotoxicity was evaluated by noting the effect of test formulation on increase in serum SGPT, SGOT, ALP activity and bilirubin level. Paracetamol hepatotoxicity was manifested by an increase lipid peroxidation, depletion of reduced glutathione (GSH) and catalase activity in liver tissue. Biochemical parameter observations were supplemented by histopathological examinations. Co-administration of Vasaguduchyadi Kwatha (decoction) protects against the paracetamol induced alteration in lipid peroxidation, restored altered serum marker enzymes and antioxidant level towards near normal. Histopathology of liver showed that test formulation attenuated the hepatocelluar necrosis and led to reduction in inflammatory cells infiltration. The results indicate hepatoprotective and antioxidant activity of Vasaguduchyadi Kwatha (decoction) against paracetamol induced toxicity. [ABSTRACT FROM AUTHOR]

Ayurveda has a large number of effective formulations for many diseases. Absence of reference standards for compound formulations is one of the hindrances on the way towards standardisation. The present study was aimed at setting up a standard profile of Vasaguduchyadi kwatha which was prepared using pharmacognostically authenticated raw drugs followed by subjecting it to detailed pharmacognostical, physicochemical and phytochemical (including High Performance Thin Layer Chromatography) analysis as per standard protocol. The observations were systematically recorded. Pharmacognostical findings (crystals, fibers, stone cells etc.) confirm the ingredients present in the finished product. Identified phytochemical components (Gallic acids, Flavonoids, Alkaloids, Phenolic compounds etc.) support the intended action of the formulation in liver diseases. The results of this study may be used as the reference standard in further research undertakings of its kind. [ABSTRACT FROM AUTHOR]

Bilwadipanchamoola one of the important component of Panchapanchamoola, have entered the catalog of endangered plants. Procuring the roots of such huge plants, which ultimately leads death of the whole plant, is not less than an offence. Hence in the present study pharmacognostical and physicochemical analysis was made to find out whether aerial parts can be used in place of roots with the reference of API. The pharmacognostical evaluation shows pitted vessels, Prismatic crystals, lignified fibres. The Physicochemical analysis shows the presence of alkaloids, coumarine glycosides. The result shows that both stem bark and root bark are having similar pharmacognostical and chemical properties. [ABSTRACT FROM AUTHOR]

Estimation of marker components in a given dosage form not only authentifies its genuineness but even indicate towards the inherent therapeutic potentials. In the present study, a simple, precise, accurate and rapid high performance thin layer chromatographic method was validated for the estimation of Aloin in liquid dosage forms. The stationary phase used was precoated silica gel 60F 254 whereas the mobile phase consisted of Ethyl acetate: Methanol: Water (10: 1.35: 1.0). The detection of spot was carried out at 254nm. The Rf value was found to be 0.65± 0.01. The linearity curve found to be linear in between 4-17 μg/spot. Proposed method can be used to determine the drug content from marketed formulations. [ABSTRACT FROM AUTHOR]

Ayurveda is literally known as science of life. Several number of medicines are explained in Ayurveda to cure the diseases. Sharangadhara in Madhyama Khanda, 9th chapter, 174th Shloka explained the preparation of Kshara Taila, which is indicated in Karna rogas like Puya Srava, Karna Nada, Karna Shoola, Badhirya, Krimi Karna and other diseases of ear and mouth also. On the other hand Apamarga Kshara is well known drug for treating the Arsha. An innovative thought to treat Arsha with a simple procedure like Basti made to combine the Apamarga Kshara in the preparation of Kshara Taila. Before clinical study the pharmacognostical and pharmaceutical analysis of the drug was done. The presence of starch grains, trichome, lignified parenchyma, prismatic crystals, stone cells and oleo resin increases the absorption of mucosa. Refractive index of Apamarga Kshara Taila was found 147.45 at 40°C, specific gravity 0.9236 at 25°C, iodine value 67.59, saponification value 105.04 and the pH value of Apamarga Kshara Taila found 5. [ABSTRACT FROM AUTHOR]