1. Neurodevelopmental Impairment Among Extremely Preterm Infants in the Neonatal Research Network
- Author
-
Adams-Chapman, Ira, Heyne, Roy J, DeMauro, Sara B, Duncan, Andrea F, Hintz, Susan R, Pappas, Athina, Vohr, Betty R, McDonald, Scott A, Das, Abhik, Newman, Jamie E, and Higgins, Rosemary D
- Subjects
Neurosciences ,Intellectual and Developmental Disabilities (IDD) ,Brain Disorders ,Perinatal Period - Conditions Originating in Perinatal Period ,Preterm ,Low Birth Weight and Health of the Newborn ,Cerebral Palsy ,Pediatric ,Clinical Research ,Infant Mortality ,Reproductive health and childbirth ,Cognitive Dysfunction ,Developmental Disabilities ,Female ,Gestational Age ,Humans ,Infant ,Extremely Premature ,Infant ,Newborn ,Male ,Motor Disorders ,Neurologic Examination ,Retrospective Studies ,Risk Factors ,Sensation Disorders ,Severity of Illness Index ,Socioeconomic Factors ,Follow-Up Study of the Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network ,Medical and Health Sciences ,Psychology and Cognitive Sciences ,Pediatrics - Abstract
Evaluate the spectrum of neurodevelopmental outcome in a contemporary cohort of extremely preterm infants. We hypothesize that the rate of severe neurodevelopmental impairment (NDI) decreases over time. Retrospective analysis of neurodevelopmental outcome of preterm infants ≤27 weeks' gestational age (GA) from a Neonatal Research Network center that completed neurodevelopmental follow-up assessments between April 1, 2011, and January 1, 2015. The Bayley Scales of Infant Development-III (BSID III) and a standardized neurosensory examination were performed between 18 and 26 months' adjusted age. Outcome measures were neurologic examination diagnoses, BSID III cognitive and motor scores, sensory impairment, and the composite outcome of NDI, based on the BSID III cognitive score (analyzed by using a cutoff of
- Published
- 2018