1. Fetal magnetic resonance imaging: supratentorial brain malformations
- Author
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Jungwhan John Choi, Janet S. Soul, Camilo Jaimes, and Edward Yang
- Subjects
Fetal magnetic resonance imaging ,Pathology ,medicine.medical_specialty ,business.industry ,Central nervous system ,Supratentorial region ,Lissencephaly ,Cortical dysplasia ,medicine.disease ,Corpus callosum ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,0302 clinical medicine ,medicine.anatomical_structure ,Holoprosencephaly ,030225 pediatrics ,Pediatrics, Perinatology and Child Health ,medicine ,Polymicrogyria ,Radiology, Nuclear Medicine and imaging ,business - Abstract
Fetal MRI is the modality of choice to study supratentorial brain malformations. To accurately interpret the MRI, the radiologist needs to understand the normal sequence of events that occurs during prenatal brain development; this includes familiarity with the processes of hemispheric cleavage, formation of interhemispheric commissures, neuro-glial proliferation and migration, and cortical folding. Disruption of these processes results in malformations observed on fetal MRI including holoprosencephaly, callosal agenesis, heterotopic gray matter, lissencephaly and other malformations of cortical development (focal cortical dysplasia, polymicrogyria). The radiologist should also be familiar with findings that have high association with specific conditions affecting the central nervous system or other organ systems. This review summarizes and illustrates common patterns of supratentorial brain malformations and emphasizes aspects that are important to patient care.
- Published
- 2020