1. Concomitant sickle cell disease and systemic lupus erythematosus: A single-center case series.
- Author
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Lapite A, Sánchez LM, Altaffer AL, Rae M, Ramirez AA, Muscal E, Yildirim-Toruner C, and Tubman VN
- Subjects
- Adolescent, Female, Humans, Young Adult, Anemia, Sickle Cell complications, Lupus Erythematosus, Systemic complications
- Abstract
Sickle cell disease (SCD) and systemic lupus erythematosus (SLE) are two uncommon disorders each characterized by multisystemic manifestations. Individuals with SCD exhibit abnormalities in the complement pathway, which may predispose patients to develop autoimmune disorders such as SLE. As many manifestations of SLE mimic those of SCD, diagnosis and therapeutic management of SLE in a patient with known SCD may be delayed. In this study, we describe our institutional experience of diagnosing and managing concomitant SCD and SLE. We offer insights into the complex interplay between these conditions to enhance early recognition and effective management of concurrent SCD and SLE., (© 2024 Wiley Periodicals LLC.)
- Published
- 2024
- Full Text
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