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BACKGROUND: Metastasis to the oral cavity is infrequent, representing 1 to 3% of head and neck cases. The types of cancer that commonly cause metastasis to the mouth are lung, kidney, and prostate for men, and breast, kidney, and colon for women. The clinical presentation depends on the affected site and varies from an evident tumor to a slight swallow mimicking a reactive lesion, accompanied by pain and paresthesia. CLINICAL CASE: A 59-year-old woman evaluated in the Pathology and Oral Medicine Clinic of the Autonomous Metropolitan University of the City, diagnosticated with oral metastasis from renal carcinoma. CONCLUSION: Clinical findings lead to an accurate diagnosis; it is important to offer the appropriate treatment, by the specialist in Pathology and Oral Medicine, as part of the multidisciplinary team, to ensure a better quality of life in this type of patient. [ABSTRACT FROM AUTHOR]

Background: Ductal cell carcinoma is an uncommon subtype of aggressive renal neoplasia arising from the medullary collecting ducts, which have been described in different countries and ethnic groups. Very few series of this tumor have been reported, and most publications in the medical literature deal with single cases. Patients and method: We present the clinicopathological findings of 10 cases collected during the last decade. The patients were 6 males and 4 females that ranged in age from 34 to 65 years (mean: 51.3 years). Hematuria, hidronephrosis, lumbar pain, renal lithiasis and weight loss were the main clinical symptoms related to the renal tumors. Four patients died due to the neoplasia, and in three of them widespread metastases were found in the postmortem examination. Results: Histologically, all the tumors showed a high Fuhrman nuclear-grade and were composed of a varied pattern of tubular, tubulopapillary, microcystic and trabecular epithelial cells growing in a desmoplastic stroma with mixed inflammation. Additionally in three tumors, we observed secretory metaplasia with signet ring cells, sarcomatoid changes and hyaline globules respectively. The tumor cells exhibited typical and consistent immunohistochemical positive staining with antibodies for cytokeratin 7, cytokeratin AE1/AE3 and Ulex europaeus lectin. Conclusions: Histopathological features together with the immunohistochemical staining for cytokeratin 7 and Ulex europaeus are in our view, the most important findings for the identification of renal ductal carcinoma that is an entity not yet well recognized by some clinicians and pathologists. [ABSTRACT FROM AUTHOR]