1. Experimental-computational study of fibrous particle transport and deposition in a bifurcating lung model
- Author
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Xiaopu He, Wenqi Zhong, Yu Feng, Josin Tom, Clement Kleinstreuer, and Xiaole Chen
- Subjects
Materials science ,010504 meteorology & atmospheric sciences ,business.industry ,General Chemical Engineering ,02 engineering and technology ,021001 nanoscience & nanotechnology ,01 natural sciences ,Particle transport ,Molecular physics ,Volumetric flow rate ,Optics ,Gravitational effect ,Deposition (phase transition) ,General Materials Science ,Fiber ,0210 nano-technology ,business ,Bifurcation ,Stokes number ,0105 earth and related environmental sciences ,Particle deposition - Abstract
Experiments carried out using a lung model with a single horizontal bifurcation under different steady inhalation conditions explored the orientation of depositing carbon fibers, and particle deposition fractions. The orientations of deposited fibers were obtained from micrographs. Specifically, the effects of the sedimentation parameter ( γ ), fiber length, and flow rate on orientations were analyzed. Our results indicate that gravitational effect on deposition cannot be neglected for 0.0228 γ γ for values 0.0228 γ γ suggests these characteristics can be used to estimate fiber deposition in the lower airways. Computer simulations with sphere-equivalent diameter models for the fibers explored deposition efficiency vs. Stokes number. Using the volume-equivalent diameter model, our experimental data for the horizontal bifurcation were replicated. Results for particle deposition using a lung model with a vertical bifurcation indicate that body position also affects deposition.
- Published
- 2016
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