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1. Co-infections with liver fluke and Helicobacter species: A paradigm change in pathogenesis of opisthorchiasis and cholangiocarcinoma?

Author

Sripa, Banchob, Deenonpoe, Raksawan, and Brindley, Paul J.

Subjects
*OPISTHORCHIS viverrini, *LIVER flukes, *HELICOBACTER pylori infections, *CHOLANGIOCARCINOMA, *CANCER cells, *DIAGNOSIS, *CANCER
Abstract

Infection with the fish-borne liver fluke Opisthorchis viverrini is classified by the International Agency for Research on Cancer as a Group 1 carcinogen: definitely carcinogenic in humans. Cofactors likely contribute to bile duct cancer (cholangiocarcinoma) caused by this infection. Here we review recent findings that address the role of liver fluke associated H . pylori in hepatobiliary disease and malignancy. We hypothesize that co-infection by O . viverrini and the bacillus Helicobacter pylori is central of liver fluke infection associated cholangiocarcinoma. [ABSTRACT FROM AUTHOR]

Published
2017
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