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Given the relevance of museums in promoting cultural, tourism and economic development in local territories, we investigate the influence of both spatial and non‐spatial interactions on museum attractiveness. In particular, we assess whether non‐spatial collaborations such as partnerships and networking, contribute to enhancing their level of competitiveness and if spatial dependence occurs among neighbouring museums. Additionally, we differentiate the analysis by considering various location typologies, that is, sites located in highly attractive and remote areas. Findings from this study can assist policy‐makers in designing ad hoc strategies to encourage the active role of museums in their local context. [ABSTRACT FROM AUTHOR]

Political institutions are an essential component to explain income variation. Brazilian municipalities are characterized by a great contrast in the colonization process and its impacts on the current income level and distribution, and other development aspects. This study analyzes the spatial heterogeneity of the relationship between institutional quality and the municipalities' economic development. We use a spatial moving window method applied to weighted regressions—Geographically Weighted Regression (GWR). We find evidence that good institutions increase income and other variables related to economic development. In addition, the institutional quality influence on economic development measures is distinct across the Brazilian regions. [ABSTRACT FROM AUTHOR]

The aim of this research was to study the influence of related variety on the economic performance of Spanish provinces during the international crisis (2009–2013) and the post‐crisis period (2014–2018), with the goal of contributing to assess the validity of the skill‐relatedness approach. The research is based on labor flows in a sample of more than one million affiliated workers. Our results confirmed the influence of related variety on the growth of GDP and employment in knowledge‐based industries, in protecting against unemployment, as well as on the creation of new firms, although with marked differences according to the economic cycle. Robustness issues and possible lines of progress using this novel methodology are also discussed. [ABSTRACT FROM AUTHOR]

The goal of this study is to examine the effects of investment in human capital, as funded by EU cohesion policy, on economic development in Poland at the local (LAU 2) level, that is, at the level of municipalities. We found evidence that human capital investment has a positive effect on local revenues. This effect is stronger than what is observed for the assistance programmes not related to human capital. The impact of intervention on migration balance is in turn not significant. We also observed that the effectiveness of the assistance within the cohesion policy depends on existing regional preconditions for development. [ABSTRACT FROM AUTHOR]

This research evaluates the management efficiency of the European Structural Funds according to whether their productive orientation is based on employment or on economic and social development. The data refers to 2000–2020 for the 28 EU countries. The paper includes an analysis of the influence of the country's governance and economic freedom on the production function associated with the funds received. The results show that there is a technological gap between groups of countries defined by their goodness of governance. On the other hand, there is a positive relationship of economic freedom and the efficiency scores of the countries. [ABSTRACT FROM AUTHOR]

This paper aims at analysing how the presence of workers employed in cultural and creative industries (CCIs) is related to regional specialized diversification. From a theoretical perspective, CCIs drive economic development and local innovative capacity by facilitating processes of cross‐fertilization of ideas. This study estimates an entry model analysing the ability of Italian provinces to successfully create new sectoral specializations. The results indicate that the relationship between the share of employees in CCIs and the probability of creating new sectoral specializations is non‐linear, highlighting the need for CCIs‐led policies to achieve a certain level of critical mass to be successful. [ABSTRACT FROM AUTHOR]

Relatedness has become a key concept for studying the diversification of firms, regions and countries. However, studies tend to treat relatedness as being time‐invariant or, alternatively, consider its evolution as exogenously given. This study argues that relatedness is inherently dynamic and endogenous to technological and economic developments. Using patent data, we test the extent to which relatedness between technologies developed along co‐location and differences in technological complexity in 1980–2010. Our results show that co‐located technologies are more likely to become related over time. Moreover, our results suggest that co‐location and complexity of technologies are conducive to the intensification of relatedness over time. [ABSTRACT FROM AUTHOR]

This paper analyses the long‐term relationship between regional inequality and economic development. Our data set includes information on national and regional per capita GDP for four countries: France, Italy, Portugal and Spain, compiled on a decadal basis for the period 1860–2010. Using parametric and semiparametric regressions, our results confirm the rise and fall of regional inequalities over time although in recent decades they are on the rise again. Finally, we identify structural change as being a significant transmission mechanism of the inverted‐U relationship. The arrival of technological shocks, beginning during the onset of industrialization, and the transition from agrarian to industrial economies, would explain this result. [ABSTRACT FROM AUTHOR]

Knowledge of the determinants of self‐employment income is critical to entrepreneurial development strategies if the development goal is to increase incomes not just employment. Using American Community Survey data, unconditional quantile regression is used to investigate differences in the relationship between entrepreneurial income and an array of individual, industry, and regional characteristics across the self‐employment income distribution. Personal attributes, such as education, race, age, and gender, both explain differences in self‐employment income and vary in importance across the income distribution. Regional agglomerative effects are significantly positive and stronger at the upper end of the self‐employed income distribution. [ABSTRACT FROM AUTHOR]

This paper investigates the causal relationship between financial development and the urban–rural income gap in China. Using a bootstrap Granger panel causality analysis, the result indicates that financial development influences urban–rural income gap mainly in Eastern China. The high level of financial development in this region enables rural areas to increase its income. Our results also confirm the existence of the financial Kuznets curve in Eastern China where urban–rural income gap would be first increased and afterwards decreased by financial development. The financial development itself is not dependent on urban–rural income gap as it largely depends on government policies and economic growth. [ABSTRACT FROM AUTHOR]

Regional inequality in the process of economic growth has recently been a popular topic. This paper creatively proposes contribution decomposition methods to divide various regions' contributions into economic contribution and population contribution. The methods consider not only economic growth but also population change, which may be more effective than the traditional method that uses the per capita GDP (gross domestic product) as its single measurement indicator. Moreover, the objective is to take a step forward and reveal the spatio‐temporal evolution characteristics of regional disparities by integrating barycentre model and economic development equilibrium model. Lastly, the applicability of the research method proposed in this paper is verified by a case study of Jiangsu province, China; the results show a new regional economic pattern in Jiangsu province. [ABSTRACT FROM AUTHOR]

No abstract is available for this article. [ABSTRACT FROM AUTHOR]

Under the deep and protracted recession that plagues the Greek regions, exports have shown some positive signs of resilience. This paper explores through a spatial econometric analysis of SUR models, first, the changes that occurred in exports by the (NUTS 3 level) regions for the period 2008–2012 to offer resistance against the crisis and to stimulate growth, which entail expansion of export demand, improvement in the quality of agricultural products, deeper specialization in broad low‐technology sectors and simultaneous increases in the variety inside these sectors and second, the ability of exports to transfer their growth gains to the broader economy. [ABSTRACT FROM AUTHOR]

This paper analyses the differential impact of several territorial determinants of the economic performance of Italian provinces (NUTS 3 level). as measured by per capita GDP, export and employment growth from 1999 to 2014. It covers both the pre‐crisis and the crisis period and stresses the role of geographical proximity in shaping local performance over a wide set of explanatory variables. In order to do so, we employ, firstly, a spatial Durbin model which enables us to discriminate between direct and indirect effects and to highlight the possible contagion or crowding‐out spatial effects for each territorial dimension affecting growth. Then, we extend the analysis by allowing for the possibility of two regimes (pre‐crisis and post‐crisis). The performance of the provinces before and during the crisis relates to specific territorial components and geographic proximity appears to influence differently the results and their interpretation. [ABSTRACT FROM AUTHOR]

As cities are compelled to compete for new sources of investment and revenue, arts‐based economic development strategies have become the norm. The purpose of this paper is to revisit and reevaluate some of the conventional claims about the arts as an important economic development strategy by exploring a case study called "The Space at 2106 Main" in a rapidly gentrifying neighbourhood called West Tampa. The results of this study suggest that the arts are indeed assuming a greater role in economic policy under the auspices of West Tampa community redevelopment areas (CRA) and the direct actions of various arts related entrepreneurs. The results however, point to a mixed picture that raises difficult questions about the medium to long‐term effects of this urban redevelopment strategy, especially on the poor and mostly minority residents of West Tampa. [ABSTRACT FROM AUTHOR]

Governments use incentive programmes to attract new businesses. Due to limited resources, there are questions about which incentives are most effective. Using establishment data from California, and data on the location of disbursements through two federal programmes, we consider the effectiveness of different programmes in attracting new businesses. We find that the amount of funding through the New Markets Tax Credit programme has a significant impact on business activity but find no evidence of an effect from the Community Development Financial Institutions programme. Our results suggest that the effectiveness of these programmes depends on how they provide assistance. [ABSTRACT FROM AUTHOR]

In this paper, a flash flood that occurred in the Brazilian state of Santa Catarina in 2008 is used to investigate the existence of spatial spillovers from natural disasters in geographically‐linked areas. In order to do so, we estimated a Difference‐in‐Differences model that explicitly allows for the existence of spatial interactions within affected and unaffected regions. Our results show that municipalities directly affected by the flood suffered an 7.6% decrease in GDP per capita in the year of the disaster. Three years after the flood, however, GDP per capita rebounded back to pre‐disaster levels in all sectors but the Agricultural sector. Finally, our spatial estimations show that spillovers exist and are economically relevant. [ABSTRACT FROM AUTHOR]

Using a multi‐region, multi‐sector dynamic model of an economy with rural–urban migration fit to Turkish data, this paper explores the evolution of each region's output and factor allocation as well as inter‐regional disparities that emerge with migration. Migration or residence decision of households is endogenous with respect to regional cost‐of‐living differentials. Results show that migration slows down and dampens the shift of labour from urban manufacturing to services, despite the increase in demand for urban services. It is also established that rural–urban migration contributes positively to growth while the reallocation of labour within each region proves to be unfavourable. [ABSTRACT FROM AUTHOR]

Using a panel of 265 regions from 24 OECD countries from 1997 to 2007, we explore the impact of nation‐wide macroeconomic and structural policies on the productivity growth of subnational regions. We find that average relationships between nation‐wide policies and regional productivity growth can hide strong differentiated effects according to the distance to the frontier: relaxing employment protection legislation on temporary contracts, lowering barriers to trade and investment and increasing trade openness enhances productivity growth in lagging regions, whereas reducing barriers to entrepreneurship or higher levels of government debt has a positive effect on regions closer to the productivity frontier. [ABSTRACT FROM AUTHOR]

The territorial capital of regions is an important determinant of growth, but also of the impact of EU Cohesion Policy. First, because it can act as a filter, enhancing the impact of regional policies. Second, the latter can help building territorial capital which, in turn, will foster regional development. This work analyses the medium and long‐run relationship between the territorial capital of EU NUTS 3 regions and Cohesion Policy using data from the programming period 2000–2006. Results point out complementarities between different territorial assets of regions and the impact of EU regional policy: Cohesion Policy effectiveness is higher when investments are focused on the assets complementary to those already abundant in the region. [ABSTRACT FROM AUTHOR]

This paper studies the effect of the zone tax offset (ZTO), a place based income subsidy implemented in rural Australia since 1945. The policy was intended to improve the welfare of inhabitants and provide an incentive for settlement. Our empirical approach exploits the geographical discontinuity in the eligibility for the subsidy to identify its causal effect on population growth. Using data on population by locality from the historical censuses we find that the ZTO had a positive but only temporary effect on population growth in the targeted areas. [ABSTRACT FROM AUTHOR]

While R&D activities are known for being unevenly distributed across space, how EU policy contributed to their regional dynamics is less explored. Since the 1980s, the EU Framework Programmes (FP) have promoted and supported transnational R&D projects through open and highly competitive calls for funding driven by 'scientific excellence' regardless of location. This paper aims to show the drivers of this spatial distribution and evolution of FP participations, arguing that this depends on cumulative effects of regional economic development and growth, while scientific specialization rarely is the best strategy to improve regional competitiveness in terms of FP participations. [ABSTRACT FROM AUTHOR]

This article casts new evidence on the effects of decentralization on economic growth. Based on the literature on the effects of institutions on the economy, such effects are assumed to accrue through total factor productivity (TFP). Five variables to capture decentralization are proposed in order to overcome the recent criticisms of the empirical approaches regarding the proper measures of variables capturing decentralization. Panel data for the regions of Spain over the 1986–2010 period are used. In general, the results show that the financial autonomy and the share of regional investment in public infrastructure seem to positively affect the economic growth of Spanish regions. However, a negative effect is found for a proxy for the number of responsibilities transferred to the regions. Moreover, empirical evidence provided for three sub‐sample periods could be suggesting that the Spanish state might be around the optimal level of decentralization. Results are fairly robust to different estimation methods and measures of TFP, regardless of the assumption of constant returns to scale. [ABSTRACT FROM AUTHOR]

In this paper we study the impact of regulatory complexity, a measure of institutional quality, on the GDP, on per capita income and on the growth rate of the Italian regions. For comparative reasons we also use the duration of civil disputes as a further indicator of institutional quality used in the regressions as an alternative to the indicator of regulatory complexity. From the theoretical point of view, we use the approach of negative co‐ordination externalities, among the four sources of regulatory production that are at work at the same time. Our approach may be applied in all the countries with a multi‐level government system. Using the random effects and quantile regressions models we are able to quantify the effects of an improvement in institutional quality on the GDP and the growth rate, making a comparison between the results obtained using regulatory complexity or the duration of civil disputes as covariates. We also check for spatial dependence among variables. Econometric analysis supports the theoretical assumption that regulatory complexity is an impediment to the growth of regional GDP and per capita income. The main finding of our analysis is that a reduction in regulatory complexity would be more effective than a reduction in the duration of civil disputes in increasing the income and growth rate. This result could be useful for the policy‐maker because by reducing regulatory complexity we may obtain a considerable by‐product in the shorter duration of civil disputes. [ABSTRACT FROM AUTHOR]

This study investigates the impact of the Austin MetroRail on commercial property values. Spatial Durbin models (SDM) suggest a modest price premium associated with rail transit across the study area. A premium gradient is also presented at different distance tiers from stations. When it comes to transit‐oriented development (TOD), a synergistic effect in enlarging the premium is found: with additional $9.0/ft2, $8.6/ft2 and $5.3/ft2 at 0.25 mi, 0.25–0.5 mi and 0.5–0.75 mi, respectively. Furthermore, geographically weighted regression shows the premium is significantly higher in central business district (CBD) and TOD areas. Such recognition of the heterogeneous price effect is of use in the design of project financing and TOD strategies. [ABSTRACT FROM AUTHOR]

No abstract is available for this article. [ABSTRACT FROM AUTHOR]

Abstract: The role of creativity in local economic development has been widely discussed. The evidence on this linkage is, however, mixed. This work tries to highlight the nexus by taking into consideration a new aspect, that is, the multidimensional nature of creativity and the potential synergic and complementary effects of creative talents of different nature. The merging of talents is, indeed, a source of original, complex and synergic ideas which are at the basis of the positive relation between creativity and local development. The work addresses this issue conceptually and proves the expectations through an empirical application on Italian provinces (NUTS 3). [ABSTRACT FROM AUTHOR]

Abstract: This study presents novel evidence regarding the role of regional internet infrastructure in reducing regional per capita income disparities. We base our study on the assumptions that (1) the diffusion of information homogenizes regional economies through reducing the dissimilarities in institutions and culture, and (2) the telecommunication capacity, represented by the internet infrastructure of a region, facilitates this flow of information. Using the data from the 26 statistical NUTS‐2 regions of Turkey for the period 1999–2011, we find evidence that internet infrastructure increases the speed of regional convergence. [ABSTRACT FROM AUTHOR]

Abstract: The debate on whether institutions or geography prevail in driving economic growth has been rife (e.g., Sachs 2003 vs. Rodrik et al. 2004). Most of the empirical analyses delving into this debate have focused on world countries, whose geographical and institutional conditions differ widely. Subnational analyses considering groups of countries with, in principle, more similar institutional and geographical conditions have been limited and tended to highlight that geography is more important than institutions at subnational level. This paper aims to address whether this is the case by investigating how differences in institutional and ‘first‐nature’ geographical conditions have affected economic growth in Europe's regions in the period 1995–2009. In the analysis we use a newly developed dataset including regional quality of government indicators and geographical characteristics and employ two‐stage least squares (2SLS) and instrumental variables‐generalized method of moments (IV‐GMM) estimation techniques with a number of regional historical variables as instruments. Our results indicate that at a regional level in Europe institutions rule. Regional institutional conditions – and, particularly, government effectiveness and the fight against corruption – play an important role in shaping regional economic growth prospects. This does not imply, however, that geography is irrelevant. There is evidence of geographical factors affecting regional growth, although their impact is dwarfed by the overriding influence of institutions. [ABSTRACT FROM AUTHOR]

The aim of this paper is to examine the effects of crime on regional economic growth in Mexico. We estimate a growth model using a spatial panel data model and test for the presence and type of spatial interaction, as proposed by Elhorst. Our results suggest that a two-way spatial Durbin model best fits the data, crime exerts a negative total effect on economic growth across Mexican states, particularly homicides and robbery, and significant spillover effects seem to reinforce the negative impact on regional growth. [ABSTRACT FROM AUTHOR]

This study revisits the growth effects associated with subnational fiscal policy. This, to my knowledge, is the first attempt to address the potential endogeneity of fiscal policy control variables. More specifically, the analysis used in this study implements a general method of moments spatial dynamic panel data model estimation procedure to arrive at a more refined set of estimates for the growth effects attributed to state and local fiscal policy. In deriving the estimable equation, this study extends a factor market approach for modelling regional output into a strategic interaction framework. [ABSTRACT FROM AUTHOR]

This study estimates how highways affected industrial development in China's peripheral regions between 1998 and 2007, a period during which China experienced rapid growth in highway mileage. Highways between major cities pass through some counties but not others. Based on this difference in counties' access to highways, we conduct a difference-in-difference propensity score matching estimation, with the treatment variables being counties' highway connection status and their industrial performance before and after being connected to a highway. We find that highways promote industrial development in counties with higher output and greater investment levels. Moreover, highways have differential impacts across industries and regions. [ABSTRACT FROM AUTHOR]

We investigate the role played by different fields of academic knowledge and various types of higher education institutions in the emergence of innovative start-ups in a region. We show that education and research in the applied and natural sciences have the strongest effect on the emergence of new businesses in innovative industries. Distinguishing between different indicators for these types of knowledge, the strongest effects are found for the number of professors, the number of students and the amount of external funds attracted. [ABSTRACT FROM AUTHOR]

Employing micro-data of Dutch local business units, we show that firm characteristics such as size, economic activity, the traded product portfolio, the focus of trade involvement and the geographic pattern of trade are important determinants of recovery following the trade collapse of 2008-2009, both in terms of speed and depth. Our findings suggest that post-crisis growth is faster for trade in goods further downstream of the value chain and thus closer to the final consumer. Trade recovery at the firm-level does not crucially hinge on locational factors such as the province in which a firm is located or regional revealed comparative advantages in particular product groups. [ABSTRACT FROM AUTHOR]

This paper examines Okun's Law using a spatial panel approach on NUTS 3 data for Great Britain over the period 1985-2011. The basic specification used as a starting point for the spatial analysis is the relationship between real output growth and unemployment rate changes. This is extended to incorporate spatial lags, to test for the presence of commuting effects, and to accommodate spatial residuals dependence. We estimate various spatial panel models, controlling for heterogeneity across areas, and find consistent evidence of a significant Okun's coefficient. Results also show that spillover effects from labour mobility and interregional linkages matter and have important implications for the validity of the empirical law. [ABSTRACT FROM AUTHOR]

Regional policy-makers have long sought to attract highly-educated workers with a view to stimulating economic growth and vibrancy. Previous studies over the decades leading up to the new millennium show human capital divergence across cities, where the share of college graduates grew faster in cities that had larger initial shares of college-educated workers. However, labour markets have changed significantly post-2000, likely affecting migration decisions of highly-skilled workers. Additionally, past studies have not controlled for important changes in industry education levels and overall industry composition that may influence city-level college graduate growth. We use detailed 4-digit NAICS industry employment data combined with public micro-data to construct measures of industry skill upgrading and changes in industry composition to control for their effects on human capital growth. We find agglomeration forces, rather than initial graduate share, explains college-graduate share growth post-2000. We also decompose graduates into bachelors and postgraduate degree holders to determine whether different forces are at play on growth of graduates at different education levels. [ABSTRACT FROM AUTHOR]

The above article, published online on 4 December 2015 in Wiley Online Library (), has been retracted by agreement between the author, the journal Editor in Chief, Professor Roberta Capello, and John Wiley & Sons, Ltd. The retraction has been agreed due to overlap between this article and the following article published in Belgeo, 'Paradigm change in regional policy : towards smart specialisation? Lessons from Flanders (Belgium)' by Ties Vanthillo and Ann Verhetsel. Belgeo [Online], 1-2 | 2012, Online since 04 December 2012, connection on 29 January 2016. URL: . [ABSTRACT FROM AUTHOR]

Supply chain internationalization is promoting a new cascade of agglomeration and dispersion. Headquarter tasks agglomerate in major cities in developed countries, whereas labour-intensive tasks are shed to developing countries where off-shored tasks are geographical concentrated. The entire international supply chain is productivity and welfare-enhancing, raising the efficiency of human resource use. An international supply chain can also be a route for inclusive globalization. Such benefits are offset by potential risk of volatility deriving from idiosyncratic supply shocks triggered by powerful natural disasters and other reasons and from final demand shocks. This case study of East Asia illustrates these points. [ABSTRACT FROM AUTHOR]

In this paper, we introduce network dependence in European regional growth analyses in two new ways. First, we use detailed trade-flow data across European regions to decompose regional economic growth into two components: demand-led growth due to growing export markets and structural growth due to growing market shares in those export markets. Only structural growth, constituting on average approximately 20 per cent of total growth, is potentially affected by regionally varying locational characteristics. The second network novelty we introduce is revealed competition as a measure of regional network membership in the growth analysis. Applying a neo-classical regional growth model using geographically weighted regression, we show that the degree of revealed competition in trade and services between sectors moderates regional structural growth. Regions operating on similar international markets share more favourable structural growth prospects, with locational determinants being more - albeit still limited - significant due to similar externalities. With regional characteristics being of limited sectoral and geographical importance for structural growth, our results suggest that the recently advocated place-based development strategies of European regions should be complemented with competitive regional network strategies. [ABSTRACT FROM AUTHOR]

The current dynamics in the Western European urban system are in marked contrast with the bourgeoning literature stressing the importance of agglomeration for economic growth. This paper explores whether this is due to the rise of 'city network economies', leading to processes of borrowed size as well as the rise of agglomeration shadows in networks of cities. The spread of metropolitan functions over Western European cities is analysed. It is found that network connectivity positively enhances the presence of metropolitan functions, but local size remains the most significant determinant for most types of functions. The importance of size and network connectivity differs across metropolitan functions and across cities. [ABSTRACT FROM AUTHOR]

This paper analyses the determinants of regional economic growth in the European Union adopting a non-parametric approach. Although the local-linear kernel estimator applied does not explicitly take into account the spatial dimension of the data, it is found to be consistent in our context. In addition, the geographically weighted regression turns out to be less efficient. We obtain evidence of a non-linear relationship between regional growth and its determinants in the form of parameter heterogeneity and threshold effects. These non-linearities mainly affect the initial productivity of labour, the human capital endowment and, as a novelty, the level of infrastructures. [ABSTRACT FROM AUTHOR]

This paper analyses patterns in regional inequality within and between Malaysia's 14 states, drawing upon estimates of Kuznets/Williamson curves, σ- and β-convergence and spatial spillovers. The path of regional inequality contradicts Kuznets predictions. Regional inequality initially fell but has subsequently risen with further economic development. While Malaysian governments have been successful at reducing poverty, they have been unable to curtail regional inequality in the long run. [ABSTRACT FROM AUTHOR]

Copyright of Papers in Regional Science is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The article offers the author's perspective on the significance of efficiency and modernization as the goals for the journal's improvement. The author commends the journal's decision with regards to the reviewing process of the editorial board. The author adds that the journal's savings of an on-line version will allow them to increase the number of issues annually and decrease the long time that takes between the acceptance date and publication.

Copyright of Papers in Regional Science is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Papers in Regional Science is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)