1. A vicious cycle of acute catecholamine cardiomyopathy and circulatory collapse secondary to pheochromocytoma
- Author
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Otusanya, Olufisayo, Goraya, Harmeen, Iyer, Priyanka, Landi, Kristen, Tibb, Amit, and Msaouel, Pavlos
- Subjects
Biomedical and Clinical Sciences ,Clinical Sciences ,Rare Diseases ,Cardiovascular ,Heart Disease ,2.1 Biological and endogenous factors ,Aetiology ,Biomedical and clinical sciences - Abstract
Acute catecholamine cardiomyopathy is an uncommon, life-threatening manifestation of pheochromocytoma. The massive release of catecholamines from the adrenal medulla and their toxic effects on the coronary vessels and the cardiac myocytes play a significant role in the pathogenesis of cardiomyopathy in patients with pheochromocytoma. Severe manifestations, such as acute catecholamine cardiomyopathy, may be the initial presentation, especially in unsuspected and untreated pheochromocytoma cases. The clinical course of catecholamine-induced cardiomyopathy is unpredictable as patients may rapidly deteriorate into circulatory collapse and multisystem crisis. We report a case of a 25-year-old man who presented with catecholamine-induced cardiomyopathy.
- Published
- 2015