Search

Your search keyword '"Garnero, P"' showing total 38 results
Start Over Author "Garnero, P" Journal osteoarthritis and cartilage
38 results on '"Garnero, P"'

16. Associations of clinical and biomarker variables with cartilage damage in painful pre-radiographic knee osteoarthritis. results from a population-based study

Author

Cibere, J., primary, Sayre, E.C., additional, Esdaile, J.M., additional, Thorne, A., additional, Kopec, J.A., additional, Singer, J., additional, Nicolaou, S., additional, Garnero, P., additional, Poole, A.R., additional, Kraus, V.B., additional, Saxne, T., additional, Wong, H., additional, and Guermazi;, A., additional

Published
2013
Full Text
View/download PDF

17. Association of biomarkers with osteoarthritis progression based on MRI: results from the Vancouver knee osteoarthritis progression (KOAP) study

Author

Cibere, J., primary, Guermazi, A., additional, Poole, A.R., additional, Kraus, V.A., additional, Garnero, P., additional, Saxne, T., additional, Sayre, E.C., additional, Esdaile, J.M., additional, Thorne, A., additional, Kopec, J.A., additional, Singer, J., additional, Nicolaou, S., additional, and Wong, H., additional

Published
2013
Full Text
View/download PDF

22. 113 ANALYSIS OF 31 BIOMARKERS AND BIOMARKER FACTORS IN PRE-RADIOGRAPHIC AND RADIOGRAPHIC KNEE OSTEOARTHRITIS: RESULTS OF A POPULATION-BASED STUDY USING MRI

Author

Cibere, J., primary, Visvanathan, S., additional, Baribaud, F., additional, Ma, K., additional, Zhang, H., additional, Wong, H., additional, Thorne, A., additional, Singer, J., additional, Poole, A.R., additional, Garnero, P., additional, Kopec, J., additional, Guermazi, A., additional, Nicolaou, S., additional, and Esdaile, J.M., additional

Published
2009
Full Text
View/download PDF

34. P224 IDENTIFICATION OF EARLY KNEE OSTEOARTHRITIS: RESULTS FROM THE DEVELOPMENT OF A MODEL FOR THE DIAGNOSIS OF EARLY KNEE OSTEOARTHRITIS (MODEKO) STUDY

Author

Cibere, J., primary, Zhang, H., additional, Thorne, A., additional, Wong, H., additional, Kopec, J.A., additional, Singer, J., additional, Guermazi, A., additional, Peterfy, C., additional, Nicolaou, S., additional, Munk, P., additional, Garnero, P., additional, Poole, A.R., additional, Lobanok, T., additional, Kraus, V.B., additional, Way, A., additional, Saxne, T., additional, and Esdaile, J.M., additional

Published
2006
Full Text
View/download PDF

38. Knee cartilage defects: association with early radiographic osteoarthritis, decreased cartilage volume, increased joint surface area and type II collagen breakdown.

Author

Ding C, Garnero P, Cicuttini F, Scott F, Cooley H, and Jones G

Subjects
Adult, Anthropometry methods, Cartilage, Articular injuries, Cross-Sectional Studies, Female, Humans, Magnetic Resonance Imaging methods, Male, Middle Aged, Osteoarthritis, Knee metabolism, Patella pathology, Severity of Illness Index, Tibia pathology, Cartilage, Articular pathology, Collagen Type II metabolism, Knee Joint pathology, Osteoarthritis, Knee pathology
Abstract

Objective: To generate hypotheses regarding the associations between knee cartilage defects and knee radiographic osteoarthritis (ROA), cartilage volume, bone size and type II collagen breakdown in adults., Methods: A cross-sectional convenience sample of 372 male and female subjects (mean age 45 years, range 26-61) was studied. Knee cartilage defect score (0-4) and prevalence (a defect score of > or =2), cartilage volume, and bone surface area were determined using T1-weighted fat saturation MRI. Urinary levels of C-terminal crosslinking telopeptide of type II collagen (U-CTX-II) were measured by enzyme-linked immunosorbent assay. Height, weight and ROA were measured by standard protocols., Results: In multivariate analysis, the severity and prevalence of knee cartilage defects were significantly and independently associated with tibiofemoral osteophytes (regression coefficient (beta): +0.86 to +1.31/unit, odds ratio (OR): 2.97-3.68/unit, all P<0.05 with the exception of OR in lateral tibiofemoral compartment) and tibial bone area (beta: +0.11 to +0.25/cm2; OR: 1.33-1.58/cm2, all P<0.01). Knee cartilage defects were inconsistently associated with joint space narrowing after adjustment for osteophytes but consistently with knee cartilage volume (beta: -0.27 to -0.70/ml; OR: 0.16-0.56/ml, all P<0.01 except for OR at lateral tibial cartilage site P=0.06). Lastly, knee cartilage defect severity was significantly associated with U-CTX-II (Partial r=+0.18, P<0.001 for total cartilage defect score)., Conclusion: Osteophytes and increasing knee bone size may be causally related to knee cartilage defects. Furthermore, knee cartilage defects may result in increased cartilage breakdown leading to decreased cartilage volume and joint space narrowing suggesting an important role for knee cartilage defects in early knee OA.

Published
2005
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results