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Background: The current study situation regarding the duration of systemic antibiotic treatment for spondylodiscitis is inhomogeneous and varies between 4-12 weeks. Due to the many undesirable side effects the aim is to achieve complete healing without recurrence or hematogenous scatter within the shortest possible period of time. The present pilot study investigated whether the additional application of a local antibiotic carrier to the surgically treated intervertebral disc space can contribute to a further reduction of treatment duration., Material and Methods: In the pilot study 20 patients with acute spondylodiscitis and indications for surgical intervention were included. Surgical treatment was carried out by dorsal instrumentation, radical debridement of the site of infection, and cage interposition in the affected disc space. The remaining disc space was filled with homologous cancellous bone and antibiotic-loaded calcium sulfate hydroxyapatite pellets. A classification into a long-term and a short-term antibiotic group was performed. Both groups initially received a 10-day parenteral antibiotic administration. This was followed by oral antibiotics for 2 or 12 weeks, depending on the group. During the 12-month follow-up inflammation parameters, the local infection situation as well as the bony fusion and antibiotic tolerance were regularly checked., Results: The average age of the patients was 66.7 ± 11.2 years. Intraoperative detection of pathogens was successful in 65%. In 60% the antibiotic carrier was loaded with gentamicin, in 40% with vancomycin. At follow-up, all patients except one in the short-term antibiotic group had inflammation parameters within the normal range after 3 months. In the long-term antibiosis group, two patients still showed elevated infection values after 3 months, otherwise the values were within the normal range. After 12 months a complete cure of the infection was achieved in all patients. Antibiotic treatment intolerance occurred in 10% of the short-term antibiotic group and in 50% of the long-term group., Conclusion: The results of the present pilot study show that with the additional use of absorbable local antibiotic carriers in the surgical treatment of bacterial spondylodiscitis it is possible to shorten the duration of systemic antibiotic treatment to 3 weeks. This can reduce the side effects and incompatibility of treatment and still achieve similar healing results.

Background: The reconstruction of bony defects during endoprosthesis revision surgery using "impaction bone grafting" leads to the possibility of a longstanding osseous integration to achieve good clinical results. Native allogeneic cancellous bone is often used for the procedure. This study examines the influence of thermodisinfection on the impaction behaviour of cancellous bone of different geometries and on the cement distribution., Methods: The cancellous bone was obtained from the femoral heads of 7‑month old pigs. One half of the head was thermodisinfected while the other remained native. Bone chips with sizes of 3-5, 5-8 and 8-10 mm were produced. The impaction was performed in a cylinder model with an internal diameter of 30 mm and with standardized impaction force using an impactor with a weight of 1450 g. The best particle combination was used for the subsequent computer tomography examination of the cement distribution and the contact surface to the bone in different parts of the shaft in seven investigations. For statistic measurements two-dimensional variance analysis including repetitions of measurement and Bonferroni correction, the LSD post-hoc-zest and the Mann Whitney U Test were used. The error probability was set at α = 5%. The SPSS® for Windows software was used for the statistical analysis., Results: The distribution of the cancellous and compacted bone also along the shaft revealed no significant difference between thermodisinfected and native cancellous bone at different levels (p > 0.05). Impacted native cancellous bone showed less inclusion of air, which resulted in a better distribution of density compared with thermodisinfected bone overall (p < 0.001). In the distal shaft area the cement volume was significantly larger in conjunction with the native bone. The overall area of cement penetration appeared to be significantly larger for native cancellous bone (p < 0.001)., Conclusions: The impaction of thermodisinfected and native cancellous bone showed greater deformation of the processed bone without any significant difference in the maximum density reached at different levels. Cement volume and cement penetration were pronounced proximally in native and processed cancellous bone. The cement distribution was significantly more distal for the native bone. Distally, the stabilization of the shaft appears to be increasingly dependent on the density of the impacted spongiosa, while proximally, the penetration of the cement into cancellous bone seems to correlate with porosity.

The increasing number of people having joint replacements will lead to increasing numbers of revision operations. The transplantation of allogeneic bones might reconstruct bone defects and improve long-term anchorage of the implant. A sufficient primary stability of the implanted construct is necessary to achieve osseous incorporation as well as tight contact between the implanted allogeneic and host bones. Transplantation of bone can contribute to downgrading acetabular defects and so avoid bigger reinforcement implants. An improvement of bone stock due to reconstruction of femoral bony defects might also reduce the size of the stem necessary since the indication might be limited in case of extensive bone defects. According to good longterm results of modular revision stems the Impaction-Bone-Grafting has not yet generally been established.

Hemangiomas are benign tumors, which are mainly composed of neoplastic blood vessels. The exact pathogenesis is still unclear. They are the most common benign spinal tumors and also occur less commonly in the bones of the extremities. Hemangiomas are often clinically asymptomatic and are diagnosed as incidental findings. Women are affected more frequently than men (2:1). The X‑ray and computed tomography (CT) diagnostics typically demonstrate the classical honeycombing or vertically orientated lucencies separated by thickened cancellous bone in the affected skeletal section. Vertebral hemangiomas are hyperintense in both T1 and T2-weighted magnetic resonance imaging (MRI). The treatment of vertebral hemangiomas ranges from irradiation, embolization and vertebroplasty to operative decompression, resection of the tumor and instrumented stabilization. In the long bones intralesional curettage and bone grafting with additive osteosynthesis is the main treatment modality. The prognosis for osseous hemangiomas is good.

Introduction: Determination of the extent of spinal fusion for lumbar degenerative diseases is often difficult due to minor pathologies in the adjacent segment. Although surgical intervention is required, fusion seems to be an overtreatment. Decompression alone may be not enough as this segment is affected by multiple factors such as destabilization, low grade degeneration and an unfavorable biomechanical transition next to a rigid construct. An alternative surgical treatment is a hybrid construct, consisting of fusion and implantation of an interlaminar stabilization device at the adjacent level. The aim of this study was to compare long-term clinical outcome after lumbar fusion with a hybrid construct including an interlaminar stabilization device as "topping-off"., Materials and Methods: A retrospective analysis of 25 lumbar spinal fusions from 2003 to 2010 with additional interlaminar stabilization device was performed. Through a matched case controlled procedure 25 congruent patients who received lumbar spinal fusion in one or two levels were included as a control group. At an average follow-up of 43 months pre- and postoperative pain, ODI, SF-36 as well as clinical parameters, such as leg and back pain, walking distance and patient satisfaction were recorded., Results: Pain relief, ODI improvement and patient satisfaction was significantly higher in the hybrid group compared to the control group. SF-36 scores improved in both groups but was higher in the hybrid group, although without significance. Evaluation of walking distance showed no significant differences., Discussion: Many outcome parameters present significantly better long-term results in the hybrid group compared to sole spinal fusion. Therefore, in cases with a clear indication for lumbar spinal fusion with the need for decompression at the adjacent level due to spinal stenosis or moderate spondylarthrosis, support of this segment with an interlaminar stabilization device demonstrates a reasonable treatment option with good clinical outcome. Also, the length of the fusion construct can be reduced allowing for a softer and more harmonic transition.

Introduction: For the treatment of isthmic spondylolisthesis two alternative interbody fusion techniques are available, the dorsoventral interposition in ALIF technique and the dorsal access interposition in PLIF technique. Due to the complications of anterior lumbar surgery and in order to avoid a second operation, the dorsoventral fusion technique is becoming uncommon and mainly a pure dorsal supply is performed. The aim of the study was to compare the clinical long-term results of both treatment techniques., Materials and Methods: 138 patients were treated surgically between 2003 and 2012 in symptomatic isthmic spondylolysis in L5/S1 with a Meyerding degree of I-III. 72 patients were evaluated finally (ALIF n = 25 and PLIF n = 47). The average follow-up period was 7.9 years for the ALIF group and 5.6 years for the PLIF group. In both groups the average drug consumption, duration of recovery, resumption of work and resumption of sport activities was recorded., Results: The results showed an extended time of surgery and a prolonged hospitalization of 5.4 days for the ALIF group. The ODI had a greater improvement in the PLIF group but this difference was not significant. The VAS was reduced in both groups. 36.8 % of the ALIF group and 44.7 % of the PLIF group reported a reduced pain medication postoperatively. The average recovery was 16 weeks for both groups. 29 % of PLIF and 9 % of ALIF patients had no pain relief. ALIF patients were able to get back to work after 149 days and the PLIF patients after 178 days. 31 % of the PLIF group and 13 % of the ALIF group were not able to return back to work. Revisions of fusion and the rate of wound revisions were increased in the PLIF group, adjacent segment diseases occurred more frequently in the ALIF group., Conclusion: Both treatment and fusion techniques (ALIF/PLIF) were able to achieve a significant pain relief and reduced consumption of pain medication postoperatively. The recovery period was similar in both groups, but there were differences regarding the date of return to work, hospitalization, duration of surgery and ODI score. Neither of the two methods could show a definite advantage.

Introduction: The number of spinal surgeries has increased significantly in the last decade, which has led to a correlating increase in the number of problems related to wound healing infection. Current literature has reported a spinal wound infection rate of 0.4 to 20 %. The gold standard for surgical restoration of the infection is to use supportive antibiotics, but this concept of wound management in infections is often not sufficiently standardized and shows a large variance between individual clinics. The present study is to first collect data on the number of wound infections, the clinic's internal standards, the use of methods and tools and the management of revisions in Germany., Material and Methods: A questionnaire has been designed for detecting the number of postoperative wound infections, which need to be treated surgically, and the various treatment regimens used. The questionnaire was sent to all members of the DWG (n = 1275). An example of the questionnaire was to determine clinical internal standards and the procedure for the initial treatment of wound infection, the procedure for second look surgery and the number of revisions requested to infection healing., Results: The study has accepted 67 answer sheets covering a period from June 2013-November 2013. On average, the participating hospitals perform 582 spinal operations and an average of 8 revision surgeries due to infection annually. The average rate of infection was 1.7 %. 55 % reported having no fixed standard of care. 97 % reported wound irrigation and debridement during the first revision. Indication for second look revisions was based on the local examination of the wound conditions. On average 2.2 revisions had been performed to reach effective wound healing. 81 % of the colleagues showed readiness to participate in a multicenter trial., Conclusion: The results show that there is a need for uniform standards in the treatment of postoperative infections. Surgical debridement and lavage have a major role in the treatment of infection. The overall rate of postoperative infections, of the clinics surveyed, was approximately 1.7 % per year. The infections were healed with approximately 2 revisions utilizing variety of different treatment strategies.

Background: Sagittal imbalance, adjacent segment degeneration, and loss of correction due to cage sintering are the main reasons for revision surgery after lumbar fusion. Based on the experience from hip and knee replacement surgery, preoperative software-assisted planning combined with the corresponding cages is helpful to achieve better long-term results., Objectives: Evaluation of the procedure regarding intraoperative application of preoperative planning and examination to what extent the planning was correct., Materials and Methods: In all, 30 patients were included in the period from September 2012 to May 2013 in an observational study, planned preoperatively with the planning software, and treated with the corresponding PLIF cages. The radiological evaluation was performed by thin-layer CT after 3 months., Results: A total of 24 (80%) patients were followed up after 3 months. In these 24 patients, the preoperative planning actually was correct in 17 cases with the intraoperatively implanted cage, which corresponds to a match of about 71%. The fusion rate for these 24 patients who underwent full examinations was 91.7%., Conclusion: The results of this observational study to evaluate the planning of intervertebral cages show positive experience with this novel therapeutic concept. Despite the limited number of participants, good results were observed for the intraoperative implementation of the planned cages and an adequate fusion rate was obtained. Irrespective of this, a software-based surgical planning must be questioned critically any time. Ultimately, it is the surgeon's responsibility to modify the planned procedure intraoperatively if necessary. Currently, the influence of this planning regarding the long-term course and the important question of adjacent segment instability remains unanswered.

Background: Posterior fusion procedures (posterior lumbar interbody fusion, PLIF; transforaminal lumbar interbody fusion, TLIF) are long-established surgical techniques for lumbar interbody fusion. They differ from anterior lumbar interbody fusion (ALIF) and extreme lateral interbody fusion (XLIF) procedures by approach and associated complications., Objectives: The posterior fusion procedures PLIF and TLIF are presented and compared with other fusion methods, including advantages and disadvantages. Furthermore, the surgical technique and their complications are described. Based on the current literature, it is discussed which surgical techniques can be used in various cases., Materials and Methods: A PubMed search of "posterior spinal fusion treatments" and the clinical experience of the authors are summarized in this review article., Results: PLIF and TLIF procedures reduced back and leg pain, restored the sagittal profile of the lumbar spine, and achieved good fusion rates and long-term stability. Advantages of the TLIF procedure include shorter operative times, less blood loss, less intraoperative risk of injury to neural structures, and shorter convalescence. Compared with the interposition of a cage in the ALIF technique, a further step with the risk of vascular injury is eliminated., Conclusions: The PLIF and TLIF procedures are almost equivalent posterior fusion procedures with high fusion rates, good long-term clinical outcomes, and low risk of complications. The TLIF procedure is slightly advantageous: lower nerve irritation rates, shorter operative times, and less extensive operation. Thus, the TLIF procedure is available for cases with single-sided pathologies and the PLIF procedure is available for bilateral compressions.

Background: The development of interbody fusion now stretches over many decades and is still not complete., Discussion: Due to the lack of appropriate implants, the initial fusions were performed via decortication of the dorsal and lateral structures of the spine, followed by placement of an autograft. Despite acceptable fusion results, better primary stability and higher fusion rates were desired. In addition, it became known that the primary load-bearing of the spine is located ventrally in the area of the corpus of the vertebrae. These considerations led to the development of the PLIF technique that was introduced by Cloward in 1953 and gained significantly in popularity. After removal of the intervertebral disc, he positioned iliac crest bone blocks between the vertebral bodies. Based on this technique and these considerations, intervertebral implants were developed in the 1970s. The so-called Bagby Basket was the first intervertebral cage that was initially used in horses with wobbler syndrome. Other milestones in the improvement of the cage designs followed, resulting in the production of different implant shapes and materials. The elastic modulus of the interbody implants approached by modern materials became more and more similar to bone, so that subsidence of cages reduced and the fusion rate could be further increased. The primary stability could be further increased with screw-rod systems, so that dorsal instrumentation became the standard in the context of PLIF and TLIF procedures today. The TLIF procedure described by Harms was a new modification and minimized complications of lumbar fusions and reduced the invasiveness of the procedure., Conclusion: Nowadays a wide variety of implants and implantation techniques are available, making interbody fusions in PLIF and TLIF techniques safe and successful procedures.

Objectives: Because international data have a low level of evidence, a variety of treatment approaches for lumbar spine fusion operations are justified based on long-established or safety aspects. The aim of this work is to present an overview of evidence-based peri- and intraoperative treatment measures to shorten the recovery and increase patient satisfaction., Materials and Methods: This review article is based on a selective literature search that also included PubMed on peri- and intraoperative treatment measures for lumbar spinal surgery., Results and Discussion: Peri- and intraoperative treatment algorithms have a significant influence on postoperative recovery and patient outcome after lumbar spinal surgery. Recent studies show that intraoperative blood loss and blood transfusion can be significantly reduced by optimizing patient positioning and dorsoventral combined warming measures to maintain body temperature. These measures are supplemented by the use of local infiltration of anesthesia and vasoconstrictive drugs at the start and high-dose administration of tranexamic acid in the early stages of the operation. Use of an epidural catheter significantly reduces postoperative, systemic analgesia use and allows rapid mobilization to be initiated. Immobilizing drain and corset treatments can be limited to complex cases. These treatment measures promote patient satisfaction, lead to high-quality, evidence-based care, and contribute to a shorter hospital stay and convalescence of the patient.

Background: Cementless humeral surface replacement arthroplasty is a viable treatment option for degenerative diseases of the shoulder joint. The aim of this prospective study was to analyse the results of this treatment option in patients younger than 55 years of age with different pathologies of the shoulder., Patients and Methods: Twenty-three patients (26 implants) treated with cementless humeral surface replacement arthroplasty were included in this study. Mean follow-up was 2.5 years (1-6 years). Ten patients had posttraumatic osteoarthritis, seven had primary osteoarthritis, and six had osteonecrosis. Patients were evaluated using the Constant score, shoulder motion, and subjective satisfaction., Results: The mean Constant score increased significantly from 33 points preoperatively (8-69 points) to 61 points postoperatively (25-83 points; p<0.0001), adjusted to age and gender from 38% (8-86%) to 70% (28-114%; p<0.0001). Significant improvement for the whole cohort was found regarding patients' pain, activity, mobility, shoulder flexion and abduction, and internal and external rotation (p<0.001). In one case, reoperation was necessary due to a superficial wound infection, and in another case, implant revision to a total shoulder replacement was performed because of glenoid erosion., Conclusion: Cementless humeral surface replacement arthroplasty is a viable bone-preserving treatment option for young and active patients. Later conversion to total shoulder replacement is possible. Good clinical results, a low complication rate, and high patient satisfaction were found in the short and mid term. Long-term investigations are necessary to confirm these observations.

Shoulder arthroplasty has proven to be a successful option in the treatment of glenohumeral osteoarthritis. Although introduced in the 1970s by Ch. Neer, resurfacing of the glenoid remains controversial. With regard to some single prospective studies total shoulder replacement (TSR) seems to be superior to humeral head replacement (HHR) in the treatment of concentric osteoarthritis. The current literature shows that TSR leads to a better shoulder function and less pain. The decision on whether to perform a TSR or HHR should be guided by the individual pathology. The final treatment should be reliable in terms of a better shoulder function, reduced pain, and good strength. The role of glenoid loosening in TSR and its impact on shoulder function in the long term remains uncertain and has to be clarified in the future.

The treatment of cuff tear arthropathy (CTA) of the shoulder is based on the patient's subjective complaints, functional deficits, and the treatment goals that result from both. Only in the second line is the radiologic morphology of joint destruction important for the surgeon's decision. Based on these aspects it is possible to discriminate three types of CTA that obviously have similar functional deficits and radiological characteristics. This symptom-based classification can offer decision guidelines for the choice of an appropriate joint replacement.For the most frequent, stable, and osteoarthritic type with pain during motion and a tolerably restricted active and passive range of motion (ROM) surface replacement or hemiarthroplasty can lead to reasonable results. In the unstable type with only minimal radiological changes of the humeral head and the chief complaint of severe restriction of active ROM and in some cases recurrent shoulder dislocations, hemiarthroplasty with a glenoid reconstruction shell or reversed prosthesis are promising. A reverse prosthesis is the implant of choice for the necrotic type of CTA with extensive destruction of the humeral head, the glenoid, and the adjacent bony structures.

Background: The current cadaver study was performed to evaluate and compare infraspinatus (ISP) vs. subscapularis (SSC) tendon transfer used for the repair of a large supraspinatus (SSP) rotator cuff defect. The main outcome measures were the range of motion and intramuscular length changes during motion., Methods: Thirteen fresh-frozen cadaver shoulders were used in the study. A supraspinatus defect extending to the apex of the humeral head (Patte size II) was created. Transosseous repair was then attempted with the ISP and with the SSC in all cases; intramuscular length changes were measured by Hall effect transducers during motion of the arm in steps of 30 degrees., Results: Repair was successful in all cases when the ISP was used, while use of the SSC resulted in a successful repair in only 8 of the 13 (61.5%). Passive range of motion did not differ between ISP and SSC. ISP was shortened during flexion and abduction in contrast to the SSC that was lengthened during flexion (p<0.05) and shortened to a lesser degree (p<0.05). Length changes during rotation were not significantly different., Conclusions: In this cadaver model the ISP proved more favorable than the SSC for covering a Patte size II SSP defect if the assumption is true that lengthening of a muscle is less favorable than shortening because of the vascularization of the tendon.

Expert assessment of tendon injuries depends on differences between private and public insurance providers in the way preexisting conditions have to be taken into account. In most cases degenerative and injury-dependent factors have to be balanced. Common tendon injuries such as Achilles and biceps tendon ruptures as well as rotator cuff tears are discussed.

Background: Post-traumatic shoulder instability in adolescence represents a very rare condition. However, most of these patients develop recurrent shoulder dislocations over time., Methods: We report about a retrospective study, which included 32 patients younger than 16 years of age. The mean follow-up was 5 years. Our evaluation focussed on patients' age at the time of first shoulder dislocation, type of injury, and the results after conservative and operative treatment., Results: After the first dislocation, all shoulders were immobilized for 3 weeks and were treated with physiotherapy afterwards. Of these 32 patients, 30 (94%) developed recurrent shoulder dislocations. Eight patients remained in a conservative regimen (age <15 years) and 21 patients were operated for persistent shoulder instability (age >15 years). The recurrence rate was 8 of 21 patients (36.5%) in the operative group and 4 of 8 patients in the conservative group. At the time of follow-up, 4 of 8 conservatively treated patients had returned to their former sports activities and 15 of 21 (71%) in the operated group., Conclusions: Our results on post-traumatic shoulder instability in adolescence show high recurrence rates in both conservative and operative groups. After adolescence, including ossification of the glenoid, operative treatment is able to decrease the recurrence rate and to increase the sports ability of these young patients.

The object of this study was to compare treatment of ruptured Achilles tendon by operative "end to end" surgery, percutaneous repair, or conservative therapy clinically; a subject of considerable controversy in the literature. These three methods were compared in 73 patients in a randomized trial between 1994 and 1996. After 2.5 years (11-41 months), the actual activities were assigned to the Hannover Achilles tendon score and the ability of doing work or sport activities was assessed. After this period, 59.3% of the patients showed good and excellent results on the Achilles tendon score, with over 79 points (open surgery 59.1%, percutaneous 60%, conservative treatment 58.3%). None of the patients reached the maximum score of 100 points. During the isometric strength tests, the patients with percutaneous repair had a lower weakening of the treated leg (8.9%) compared to the open-operated (12.7%) and non-operated patients (17.8%). Of the patients who had percutaneous surgery, 88% rated their treatment as good or excellent; those who had open surgery 77.3%, and those with conservative treatment 75%. The percutaneous group were able to resume work and sport much sooner than the other two groups. Bearing in mind the literature and these results, we have developed an algorithm for treating Achilles tendon rupture to assist decision making in daily routine. In this way, the use of percutaneous Achilles tendon repair can be carried out in most of cases.