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Start Over Author "Zhang, Dehui" Journal organic letters
4 results on '"Zhang, Dehui"'

4. One-pot thioether formation from S-nitrosothiols.

Author

Zhang D, Devarie-Baez NO, Pan J, Wang H, and Xian M

Subjects
Allyl Compounds chemistry, Disulfides chemistry, Molecular Structure, S-Nitrosothiols chemistry, Sulfides chemical synthesis
Abstract

Protein S-nitrosation is an important post-translational modification. However, the detection of S-nitrosation is still problematic because S-nitrosation products, that is, S-nitrosothiols, are unstable species. Here a new reaction which can selectively convert unstable S-nitrosothiols to stable thioethers in one-pot under very mild conditions is reported. This reaction has the potential to be applied in the detection of protein S-nitrosation.

Published
2010
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