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Your search keyword '"Miaomiao Shu"' showing total 2 results
Start Over Author "Miaomiao Shu" Journal organic letters
2 results on '"Miaomiao Shu"'

1. Synthesis of Pyrido-Fused Quinazolinone Derivatives via Copper-Catalyzed Domino Reaction

Author

Guodong Yin, Dunjia Wang, Jinkun Huang, Meilin Liu, Chaochao Yao, and Miaomiao Shu

Subjects
Reaction mechanism, 010405 organic chemistry, Organic Chemistry, 010402 general chemistry, 01 natural sciences, Biochemistry, Combinatorial chemistry, 0104 chemical sciences, chemistry.chemical_compound, chemistry, Cascade reaction, Copper catalyzed, Physical and Theoretical Chemistry, Quinazolinone, Bond cleavage
Abstract

A simple and efficient synthesis of 11H-pyrido[2,1-b]quinazolin-11-ones by Cu(OAc)2·H2O-catalyzed reaction of easily available substituted isatins and 2-bromopyridine derivatives has been developed. The reaction involves C-N/C-C bond cleavage and two C-N bond formations in a one-pot operation. This methodology is complementary to previously reported synthetic procedures, and two plausible reaction mechanisms are discussed.

Published
2016

2. Synthesis of Pyrido-Fused Quinazolinone Derivatives via Copper-Catalyzed Domino Reaction.

Author

Meilin Liu, Miaomiao Shu, Chaochao Yao, Guodong Yin, Dunjia Wang, and Jinkun Huang

Subjects
*DOMINO toppling, *QUINAZOLINONES, *PYRIDINE synthesis, *COPPER catalysts, *CHEMICAL derivatives, *SCISSION (Chemistry), *BOND formation mechanism
Abstract

A simple and efficient synthesis of 11H-pyrido[2,1-b]quinazolin-11-ones by Cu(OAc)2.H2O-catalyzed reaction of easily available substituted isatins and 2-bromopyridine derivatives has been developed. The reaction involves C-N/C-C bond cleavage and two C-N bond formations in a one-pot operation. This methodology is complementary to previously reported synthetic procedures, and two plausible reaction mechanisms are discussed. [ABSTRACT FROM AUTHOR]

Published
2016
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