Search

Free radicals generated by the decarboxylation of dimethoxydioxanecarboxylic acids derived from l-(+)-tartaric acid and l-glyceric acid added to some maleimides and acrylates with high stereoselectivity. This method provides easy access to some chiral building blocks.

The directing ability of an aziridine group for the epoxidation of adjacent double bonds is demonstrated. The aziridine group is also used to effectively protect a double bond in a cycloenone system for a short synthesis of the title compound.

A general enantioselective synthesis of the paraconic acids was developed. The key step was a highly stereoselective aldol reaction between a dioxane dithioester derived from l-tartaric acid and a suitable aldehyde.