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Your search keyword '"Hideyuki Komatsu"' showing total 2 results
Start Over Author "Hideyuki Komatsu" Journal organic letters
2 results on '"Hideyuki Komatsu"'

1. Oxidative Rearrangement of Spiro Cyclobutane Cyclic Aminals: Efficient Construction of Bicyclic Amidines

Author

Ryu Nagao, Hiromichi Fujioka, Hideyuki Komatsu, and Kenichi Murai

Subjects
Molecular Structure, Bicyclic molecule, Stereochemistry, Organic Chemistry, Amidines, Oxidative phosphorylation, Bridged Bicyclo Compounds, Heterocyclic, Ring (chemistry), Biochemistry, Cyclobutane, chemistry.chemical_compound, chemistry, Cyclization, Aminal, Spiro Compounds, Rearrangement reaction, Physical and Theoretical Chemistry, Oxidation-Reduction, Cyclobutanes, Bond cleavage
Abstract

A new rearrangement reaction of spirocyclic cyclobutane N-halo aminals is described. This process, promoted by treatment of the aminals with N-halosuccinimides (NXS, X = Br or Cl), efficiently produces bicyclic amidines by a pathway involving initial N-halogenation of one of the aminal nitrogens followed by cyclobutane ring expansion through 1,2-C-to-N migration with simultaneous N-X bond cleavage.

Published
2012
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2. Facile preparation of oxazole-4-carboxylates and 4-ketones from aldehydes using 3-oxazoline-4-carboxylates as intermediates

Author

Kenichi Murai, Hiromichi Fujioka, Hideyuki Komatsu, Tomoyo Matsushita, and Yusuke Takahara

Subjects
Aldehydes, Molecular Structure, Organic Chemistry, Carboxylic Acids, Oxazoline, Ketones, Biochemistry, chemistry.chemical_compound, chemistry, Reagent, Organic chemistry, Combinatorial Chemistry Techniques, Reactivity (chemistry), Indicators and Reagents, Physical and Theoretical Chemistry, Oxazoles, Oxazole
Abstract

A novel 2-step synthesis of oxazole-4-carboxylates from aldehydes was developed, which is characterized by the utilization of 3-oxazoline-4-carboxylates as synthetic intermediates. The facile preparation of 4-keto-oxazole derivatives from 3-oxazoline-4-carboxylates based on their interesting reactivity toward Grignard reagents is also described.

Published
2010

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