Search

Your search keyword '"Boice GN"' showing total 2 results
Start Over Author "Boice GN" Journal organic letters

Refine your results

2 results on '"Boice GN"'

1. Direct N-acetyl enamine formation: lithium bromide mediated addition of methyllithium to nitriles.

Author

Savarin CG, Boice GN, Murry JA, Corley E, DiMichele L, and Hughes D

Abstract

An improved protocol for N-acetyl enamine formation is disclosed which involves LiBr-mediated addition of MeLi to substituted nitriles. The resulting enamides are isolated in high yields and excellent purity which permits subsequent hydrogenation at very low catalyst loading.

Published
2006
Full Text
View/download PDF

2. Pseudoephedrine as a chiral auxiliary for asymmetric Michael reactions: synthesis of 3-aryl-delta-lactones.

Author

Smitrovich JH, Boice GN, Qu C, DiMichele L, Nelson TD, Huffman MA, Murry J, McNamara J, and Reider PJ

Subjects
Catalysis, Crystallography, X-Ray, Indicators and Reagents, Lactones chemistry, Magnetic Resonance Spectroscopy, Models, Molecular, Stereoisomerism, Ephedrine chemistry
Abstract

[reaction: see text] The asymmetric Michael reaction of pseudoephedrine amides is reported. The 1,5-dicarbonyl products are converted to 3-aryl-delta-lactones in a two-step reduction/lactonization sequence. This method provides access to enantiomerically enriched trans-3,4-disubstituted delta-lactones.

Published
2002
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results