1. Clear cell odontogenic carcinoma with lymph node metastasis.
- Author
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Milles M, Doyle JL, Mesa M, and Raz S
- Subjects
- Adenocarcinoma diagnostic imaging, Aged, Carcinoma, Squamous Cell diagnostic imaging, Carcinoma, Squamous Cell pathology, Cell Differentiation, Cell Transformation, Neoplastic, Female, Humans, Lymphatic Metastasis, Maxillary Neoplasms diagnostic imaging, Neoplasm Invasiveness, Odontogenic Tumors diagnostic imaging, Tomography, X-Ray Computed, Adenocarcinoma pathology, Maxillary Neoplasms pathology, Odontogenic Tumors pathology
- Abstract
Clear cell odontogenic tumors are rare. Review of the literature showed 9 cases with a prominent clear cell component. These lesions have exhibited an aggressive behavior characterized by an infiltrative local growth pattern, recurrence, or metastases. We report a case of an odontogenic tumor that exhibited a biphasic pattern and was characterized by lymph node involvement identical histologically to the primary tumor. We conclude that the presence of a clear cell component in an ameloblastomatous tumor should be viewed as a sign of de-differentiation, and that a malignancy with or without metastases should be considered and ruled out in such cases.
- Published
- 1993
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