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Objective: The impact of weight loss surgery on oral health is not clear. The aim of the present study was to investigate its impact on the risk for dental interventions. Materials and Methods: All adults who underwent metabolic surgery in Sweden between January 1, 2009 and December 31, 2018 were identified in the Scandinavian Obesity Surgery Registry (SOReg; n = 53,643). A control cohort from the general population was created, matched 10:1 on sex, age and place of residence (n = 536,430). All individuals were followed in the Swedish Dental Register regarding event rates for four types of dental intervention: restorative, endodontic and periodontal interventions, and tooth extractions. Results: The surgical cohort had increased interventional rates postoperatively regarding all studied outcomes except periodontal interventions. Dental interventions were more common in the surgical cohort both pre‐ and postoperatively. The difference between the groups increased markedly in the postoperative period. The between‐group comparison postoperatively showed increased event rates for restorations (IRR 1.8; 95% CI 1.7–1.8), extractions (1.9; 95% CI 1.9–2.0) and endodontics (2.1; 95% CI 2.0–2.1). Conclusion: The surgical intervention might cause a substantial negative impact on oral health. These results imply an important role for counselling metabolic surgery patients regarding preventive oral health measures. [ABSTRACT FROM AUTHOR]

Objectives: To analyze the effects of primary hyperparathyroidism on oral health and to investigate if the effects are linked to severity of the disease. Subjects and Methods: This prospective cohort study involved 6151 primary hyperparathyroidism patients registered in the Scandinavian Quality Registry of Thyroid, Parathyroid, and Adrenal surgery and the National Cancer Register after parathyroidectomy (exposure) during 2011–2017 (patient cohort) and 60,654 individuals without primary hyperparathyroidism (reference cohort), matched by age, gender, and county of resident at the date of parathyroidectomy. The outcomes were tooth extractions and periodontal interventions. The risk for the outcomes was assessed by Poisson regression models. Results: After adjusting for covariates, the patient cohort had a higher incidence rate of tooth extraction during the two‐year period after parathyroidectomy (IRR = 1.15; 95% CI = 1.01–1.31), but a lower incidence rate of periodontal interventions during the four‐ to six‐year period after parathyroidectomy (IRR = 0.88; 95% CI = 0.79–0.99). Furthermore, patients with more severe primary hyperparathyroidism were more likely to have tooth extractions and periodontal interventions after parathyroidectomy. Conclusions: The risk of tooth extraction increased slightly during the first two years after parathyroidectomy. Thereafter, the oral health effects subsided. Pre‐surgical serum ionized calcium levels and adenoma weight may indicate negative dental outcomes after parathyroidectomy. [ABSTRACT FROM AUTHOR]

Objectives: To externally validate a model for medication‐related dental outcomes in (a) a general older population with dementia and (b) a matched population without dementia. Subjects and Methods: This validation study used population‐based data from seven Swedish national registers (2008–2017). Individuals aged 60+ with dementia were matched to those without dementia on age, gender, and county of residence at the date of diagnosis (index date). The exposure was continuous use of xerogenic medications during the 3‐year period before index date. The primary outcome was the number of tooth extraction and restorative procedures within 3 years after index date. Results: A total of 334,220 individuals were included in the final sample. In the dementia cohort, the use of urological drugs (incidence rate ratio [IRR] 1.08, 95% CI 1.03–1.13), respiratory medicines (IRR 1.10, 95% CI 1.04–1.17), and proton‐pump inhibitors (IRR 1.09, 95% CI 1.05–1.13) was associated with the primary outcome. In the non‐dementia cohort, respiratory medicines (IRR 1.03, CI 1.00–1.05), proton‐pump inhibitors (IRR 1.06, CI 1.04–1.08), opioids (IRR 1.05, CI 1.03–1.07), and antidepressants (IRR 1.06, CI 1.04–1.08) were associated with the primary outcome. Conclusions: Although there were differences in prescription patterns, the model performed similarly in both those with and without dementia. [ABSTRACT FROM AUTHOR]