1. Optimization of diffuse correlation spectroscopy instrumental and experimental parameters based on precision targets
- Author
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Stanislaw Wojtkiewicz, Marta Zanoletti, Turgut Durduran, Udo M. Weigel, Lorenzo Cortese, Marco Pagliazzi, Martina Giovannella, Alberto Dalla Mora, Federico Ferri, Jonas B. Fischer, Fabrizio Martelli, Giuseppe Lo Presti, Hamid Dehghani, and Davide Contini
- Subjects
Photon ,Optics ,Materials science ,Tissue optics ,Physics::Instrumentation and Detectors ,business.industry ,Duration time ,Instrumentation ,Temporal resolution ,Detector ,Range (statistics) ,Diffuse correlation spectroscopy ,business - Abstract
Diffuse correlation spectroscopy (DCS) is an emerging diffuse optical technique that quantifies microvascular blood flow. In spite of the wide range of clinical/research applications, DCS instrumentation is not yet standardized. In this study, we have analyzed the effect of experimental parameters as the measurement duration time and the number of detectors, at different photon count-rates, on the precision of a DCS experiment. This provides a recipe for finding device and experimental settings that optimize the precision while balancing cost and temporal resolution.
- Published
- 2021
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