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This paper explores a series of thoughts about the meaning of intelligence in neuroscience and computer science. This work aims to present an understandable definition that fits our contemporary artificial intelligence background. The research methodology of this essay lies in existing theories of artificial intelligence, focused on computer science and neuroscience. I analyze the relationship between intelligence and neuroscience and Hawkin’s Thousand Brains Theory, an approach to show what it is an intelligent agent according to neuroscience. Here, the main result relies on the verification that intelligence is only possible in the neocortex. According to this result, the study performs a second critical analysis aiming to demonstrate why there is no artificial intelligence today.