1. Screening for Retinopathy of Prematurity: Insight into Optimizing Screening
- Author
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Agnès Soudry Faure, Catherine Creuzot-Garcher, Ninon Ternoy, Claude Speeg Schatz, Niyazi Acar, Camille Charvy, Charlotte Pallot, Alain M. Bron, Claire Langlet Muteau, Centre Hospitalier Universitaire de Dijon - Hôpital François Mitterrand (CHU Dijon), Hôpitaux Universitaires de Strasbourg, Centre des Sciences du Goût et de l'Alimentation [Dijon] (CSGA), Institut National de la Recherche Agronomique (INRA)-Université de Bourgogne (UB)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Centre National de la Recherche Scientifique (CNRS), and Université Bourgogne Franche-Comté [COMUE] (UBFC)
- Subjects
Male ,medicine.medical_specialty ,retina ,Birth weight ,Population ,Gestational Age ,Diagnostic Techniques, Ophthalmological ,03 medical and health sciences ,Cellular and Molecular Neuroscience ,0302 clinical medicine ,Medicine ,Humans ,Mass Screening ,Retinopathy of Prematurity ,030212 general & internal medicine ,[SDV.MHEP.OS]Life Sciences [q-bio]/Human health and pathology/Sensory Organs ,education ,Mass screening ,Retrospective Studies ,education.field_of_study ,medicine.diagnostic_test ,business.industry ,Obstetrics ,prematurity ,Fundus photography ,Postmenstrual Age ,Infant, Newborn ,Gestational age ,Infant ,Retinopathy of prematurity ,General Medicine ,medicine.disease ,Respiration, Artificial ,Sensory Systems ,eye diseases ,Ophthalmology ,Postnatal age ,Multivariate Analysis ,030221 ophthalmology & optometry ,Female ,business ,[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology - Abstract
Purpose: To determine the factors influencing the time from preterm birth and retinopathy of prematurity (ROP) detection to optimize the timing of the initial screening. Methods: This multicenter retrospective study enrolled preterm infants born before 32 weeks of gestational age (GA) and/or weighing less than 1,500 g between January 1, 2011, and December 31, 2015. ROP screening was performed using fundus photography with a wide-field camera. Population and follow-up characteristics were recorded. Results: Among the 1,266 preterm infants observed, 795 were retained for analysis. One hundred seventy-four (21.6%) cases of ROP were detected with the first examination performed at 32.3 ± 1.6 weeks of postmenstrual age (PMA) and 5.4 ± 1.0 weeks of postnatal age (PNA). The first signs of ROP were detected at 34.0 ± 1.9 weeks of PMA and 7.2 ± 1.8 weeks of PNA, respectively. In the multivariate analysis, an older GA, a longer duration of mechanical ventilation, and a lower birth weight were correlated with a longer time between preterm birth and ROP detection (p < 0.0001, p < 0.0001, and p = 0.0359, respectively). Conclusion: The first examination for ROP screening should be individualized to fit the first screening examination as closely as possible to the first signs of ROP in order to avoid unnecessary examinations without missing ROP.
- Published
- 2017
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