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Start Over Descriptor "visceral metastases" Journal oncology reviews
2 results on '"visceral metastases"'

1. Impact of non-pulmonary visceral metastases in the prognosis and practice of metastatic testicular germ cell tumors.

Author

Rossi, Lorena, Martignano, Filippo, Gallà, Valentina, Maugeri, Antonio, and Schepisi, Giuseppe

Subjects
*LUNG diseases, *METASTASIS, *CELL analysis, *PROGNOSIS, *DISEASE relapse
Abstract

Non-pulmonary visceral metastases, in bones, brain and liver, represent nearly the 10% of metastatic sites of advanced germ cell tumors and are associated with poor prognosis. This review article summarizes major evidences on the impact of different visceral sites on the prognosis, treatment and clinical outcome of patients with germ cell tumors. The clinic-biological mechanisms by which these metastatic sites are associated with poor clinical outcome remain unclear. The multimodality treatment showed a potential better survival, in particular in patients with relapsed disease. Patients with advanced germ cell tumors with visceral metastases should be referred to centers with high expertise in the clinical management of such disease. [ABSTRACT FROM AUTHOR]

Published
2016
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2. Impact of Non-Pulmonary Visceral Metastases in the Prognosis and Practice of Metastatic Testicular Germ Cell Tumors

Author

Lorena Rossi, Antonio Maugeri, Valentina Gallà, Filippo Martignano, and Giuseppe Schepisi

Subjects
0301 basic medicine, Oncology, lcsh:Internal medicine, Cancer Research, medicine.medical_specialty, Pathology, Poor prognosis, medicine.medical_treatment, Disease, Review, chemotherapy, 03 medical and health sciences, 0302 clinical medicine, visceral metastases, Testicular cancer, Internal medicine, medicine, In patient, lcsh:RC31-1245, Chemotherapy, business.industry, germ cell tumor, lcsh:Other systems of medicine, lcsh:RZ201-999, medicine.disease, Testicular germ cell, Review article, 030104 developmental biology, 030220 oncology & carcinogenesis, Germ cell tumors, business
Abstract

Non-pulmonary visceral metastases, in bones, brain and liver, represent nearly the 10% of metastatic sites of advanced germ cell tumors and are associated with poor prognosis. This review article summarizes major evidences on the impact of different visceral sites on the prognosis, treatment and clinical outcome of patients with germ cell tumors. The clinic-biological mechanisms by which these metastatic sites are associated with poor clinical outcome remain unclear. The multimodality treatment showed a potential better survival, in particular in patients with relapsed disease. Patients with advanced germ cell tumors with visceral metastases should be referred to centers with high expertise in the clinical management of such disease.

Published
2016

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