206 results on '"DNA-PKcs"'
Search Results
2. PARP1 and DNA-PKcs synergize to suppress p53 mutation and telomere fusions during T-lineage lymphomagenesis
3. DNA-PKcs and ATM influence generation of ionizing radiation-induced bystander signals
4. Variations in Prkdc encoding the catalytic subunit of DNA-dependent protein kinase (DNA-PKcs) and susceptibility to radiation-induced apoptosis and lymphomagenesis
5. Diminished lifespan and acute stress-induced death in DNA-PKcs-deficient mice with limiting telomeres
6. Opposite modifying effects of HR and NHEJ deficiency on cancer risk in Ptc1 heterozygous mouse cerebellum
7. Artemis is a negative regulator of p53 in response to oxidative stress
8. Differential stability of the DNA-activated protein kinase catalytic subunit mRNA in human glioma cells
9. The BAP1 nuclear deubiquitinase is involved in the nonhomologous end-joining pathway of double-strand DNA repair through interaction with DNA-PK
10. Induction of APOBEC3B expression by chemotherapy drugs is mediated by DNA-PK-directed activation of NF-κB
11. The radioprotective effect of the 24 kDa FGF-2 isoform in HeLa cells is related to an increased expression and activity of the DNA dependent protein kinase (DNA-PK) catalytic subunit
12. Spontaneous tumor development in bone marrow-rescued DNA-PKcs3A/3A mice due to dysfunction of telomere leading strand deprotection
13. DNA-PK/Chk2 induces centrosome amplification during prolonged replication stress
14. The role of insulin-like growth factor binding protein-3 in the breast cancer cell response to DNA-damaging agents
15. Regulation of DNA-dependent protein kinase by protein kinase CK2 in human glioblastoma cells
16. Frequent alteration of DNA damage signalling and repair pathways in human colorectal cancers with microsatellite instability
17. The life and death of DNA-PK
18. DNA-PK, the DNA-activated protein kinase, is differentially expressed in normal and malignant human tissues
19. Human normal peripheral blood B-lymphocytes are deficient in DNA-dependent protein kinase activity due to the expression of a variant form of the Ku86 protein
20. Regulation of DNA-dependent protein kinase activity in leukemic cells
21. Inhibiting Importin 4-mediated nuclear import of CEBPD enhances chemosensitivity by repression of PRKDC-driven DNA damage repair in cervical cancer
22. AKT inhibition impairs PCNA ubiquitylation and triggers synthetic lethality in homologous recombination-deficient cells submitted to replication stress
23. Targeting of β1 integrins impairs DNA repair for radiosensitization of head and neck cancer cells
24. Chk1 is dispensable for G2 arrest in response to sustained DNA damage when the ATM/p53/p21 pathway is functional
25. Glioblastoma multiforme: the role of DSB repair between genotype and phenotype
26. Apoptosis in malignant glioma cells triggered by the temozolomide-induced DNA lesion O6-methylguanine
27. Microsatellite instability and mutation analysis of candidate genes in urothelial cell carcinomas of upper urinary tract
28. Reduced DNA-dependent protein kinase activity in two cell lines derived from adult cancer patients with late radionecrosis
29. Multiple molecular mechanisms contribute to radiation sensitivity in mantle cell lymphoma
30. A monoclonal antibody specific for BK virus large T-antigen (clone BK.T-1) also binds the human Ku autoantigen
31. Absence of major defects in non-homologous DNA end joining in human breast cancer cell lines
32. Homologous recombination as a potential target for caffeine radiosensitization in mammalian cells: reduced caffeine radiosensitization in XRCC2 and XRCC3 mutants
33. Rapamycin and p53 act on different pathways to induce G1 arrest in mammalian cells
34. EZH2 inhibition sensitizes MYC-high medulloblastoma cancers to PARP inhibition by regulating NUPR1-mediated DNA repair
35. The Ku70-SIX1-GPT2 axis regulates alpha-ketoglutarate metabolism to drive progression of prostate cancer
36. Systematic investigation of BRCA1-A, -B, and -C complexes and their functions in DNA damage response and DNA repair
37. The ASH1L-AS1-ASH1L axis controls NME1-mediated activation of the RAS signaling in gastric cancer
38. Targeting CK2-mediated phosphorylation of p53R2 sensitizes BRCA-proficient cancer cells to PARP inhibitors
39. A DNA-PK phosphorylation site on MET regulates its signaling interface with the DNA damage response
40. Extrachromosomal circular DNA in colorectal cancer: biogenesis, function and potential as therapeutic target
41. A synthetic lethal strategy using PARP and ATM inhibition for overcoming trastuzumab resistance in HER2-positive cancers
42. Noncoding RNA actions through IGFs and IGF binding proteins in cancer
43. ATR and CDK4/6 inhibition target the growth of methotrexate-resistant choriocarcinoma
44. eIF3a regulation of mTOR signaling and translational control via HuR in cellular response to DNA damage
45. Cancer-associated fibroblast-induced lncRNA UPK1A-AS1 confers platinum resistance in pancreatic cancer via efficient double-strand break repair
46. Mitotic phosphorylation of tumor suppressor DAB2IP maintains spindle assembly checkpoint and chromosomal stability through activating PLK1-Mps1 signal pathway and stabilizing mitotic checkpoint complex
47. Caspase-2 regulates S-phase cell cycle events to protect from DNA damage accumulation independent of apoptosis
48. O-GlcNAc modified-TIP60/KAT5 is required for PCK1 deficiency-induced HCC metastasis
49. PPIP5K2 promotes colorectal carcinoma pathogenesis through facilitating DNA homologous recombination repair
50. STING protects breast cancer cells from intrinsic and genotoxic-induced DNA instability via a non-canonical, cell-autonomous pathway
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