953 results
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2. Cooperation between SIX1 and DHX9 transcriptionally regulates integrin-focal adhesion signaling mediated metastasis and sunitinib resistance in KIRC
3. Robustness of cancer microbiome signals over a broad range of methodological variation
4. Targeting DGAT1 inhibits prostate cancer cells growth by inducing autophagy flux blockage via oxidative stress
5. Alleviating hypoxia to improve cancer immunotherapy
6. p63: a crucial player in epithelial stemness regulation
7. Methyltransferase like 3 inhibition limits intrahepatic cholangiocarcinoma metabolic reprogramming and potentiates the efficacy of chemotherapy
8. TRIM28 promotes luminal cell plasticity in a mouse model of prostate cancer
9. Upregulation of GALNT7 in prostate cancer modifies O-glycosylation and promotes tumour growth
10. A novel Pyk2-derived peptide inhibits invadopodia-mediated breast cancer metastasis
11. The strategy and clinical relevance of in vitro models of MAP resistance in osteosarcoma: a systematic review
12. AGO4 suppresses tumor growth by modulating autophagy and apoptosis via enhancing TRIM21-mediated ubiquitination of GRP78 in a p53-independent manner
13. Combination strategies with PARP inhibitors in BRCA-mutated triple-negative breast cancer: overcoming resistance mechanisms
14. Targeting DDX3X eliminates leukemia stem cells in chronic myeloid leukemia by blocking NT5DC2 mRNA translation
15. Enhancing low-dose radiotherapy efficacy with PARP inhibitors via FBL-mediated oxidative stress response in colorectal cancer
16. Super-enhancer MYCNOS-SE promotes chemoresistance in small cell lung cancer by recruiting transcription factors CTCF and KLF15
17. EphA2 regulates vascular permeability and prostate cancer metastasis via modulation of cell junction protein phosphorylation
18. Breathing new insights into the role of mutant p53 in lung cancer
19. Profiling the cancer-prone microenvironment in a zebrafish model for MPNST
20. Nuclear versus cytoplasmic IKKα signaling in keratinocytes leads to opposite skin phenotypes and inflammatory responses, and a different predisposition to cancer
21. Hypoxia induced cellular and exosomal RPPH1 promotes breast cancer angiogenesis and metastasis through stabilizing the IGF2BP2/FGFR2 axis
22. Manipulating the EphB4-ephrinB2 axis to reduce metastasis in HNSCC
23. CREB1-BCL2 drives mitochondrial resilience in RAS GAP-dependent breast cancer chemoresistance
24. The influence of endothelial metabolic reprogramming on the tumor microenvironment
25. The Ku70-SIX1-GPT2 axis regulates alpha-ketoglutarate metabolism to drive progression of prostate cancer
26. Sex-dependent differences in hematopoietic stem cell aging and leukemogenic potential
27. Chimeric protein EWS::FLI1 drives cell proliferation in Ewing Sarcoma via aberrant expression of KCNN1/SK1 and dysregulation of calcium signaling
28. Methylmalonic acid induces metabolic abnormalities and exhaustion in CD8+ T cells to suppress anti-tumor immunity
29. GPA33 expression in colorectal cancer can be induced by WNT inhibition and targeted by cellular therapy
30. Hypoxia-dependent recruitment of error-prone DNA polymerases to genome replication
31. Transcriptional regulation by MYC: an emerging new model
32. Dependence of PAX3-FOXO1 chromatin occupancy on ETS1 at important disease-promoting genes exposes new targetable vulnerability in Fusion-Positive Rhabdomyosarcoma
33. Zinc ions activate AKT and promote prostate cancer cell proliferation via disrupting AKT intramolecular interaction
34. The protection of UCK2 protein stability by GART maintains pyrimidine salvage synthesis for HCC growth under glucose limitation
35. A safe haven for cancer cells: tumor plus stroma control by DYRK1B
36. Finding a needle in a haystack: functional screening for novel targets in cancer immunology and immunotherapies
37. Targeting aldehyde dehydrogenase ALDH3A1 increases ferroptosis vulnerability in squamous cancer
38. S100A8/A9 innate immune signaling as a distinct mechanism driving progression of smoking-related breast cancers
39. Evidence of DNA methylation heterogeneity and epipolymorphism in kidney cancer tissue samples
40. Oncogenic potential of truncated-Gli3 via the Gsk3β/Gli3/AR-V7 axis in castration-resistant prostate cancer
41. m6A-modified circSTX6 as a key regulator of cervical cancer malignancy via SPI1 and IL6/JAK2/STAT3 pathways
42. Pyrithione zinc alters mismatch repair to trigger tumor immunogenicity
43. Global profiling of alternative splicing in non-small cell lung cancer reveals novel histological and population differences
44. Mevalonate kinase inhibits anti-tumor immunity by impairing the tumor cell-intrinsic interferon response in microsatellite instability colorectal cancer
45. CBL0137 and NKG2A blockade: a novel immuno-oncology combination therapy for Myc-overexpressing triple-negative breast cancers
46. A TBX2-driven signaling switch from androgen receptor to glucocorticoid receptor confers therapeutic resistance in prostate cancer
47. PRMT5-regulated splicing of DNA repair genes drives chemoresistance in breast cancer stem cells
48. Mitochondrial unfolded protein response-dependent β-catenin signaling promotes neuroendocrine prostate cancer
49. Identification of novel germline mutations in FUT7 and EXT1 linked with hereditary multiple exostoses
50. Lack of dominant-negative activity for tumor-related ZNRF3 missense mutations at endogenous levels
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