1. In Reply.
- Author
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Judy, Amy E. MD, MPH, McCain, Christy L. MPH, Lawton, Elizabeth S. MHS, Morton, Christine H. PhD, Main, Elliott K. MD, Druzin, Maurice L. MD, Judy, Amy E, McCain, Christy L, Lawton, Elizabeth S, Morton, Christine H, Main, Elliott K, and Druzin, Maurice L
- Subjects
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CALCIUM antagonists , *HYPERTENSION in pregnancy , *HYPERTENSION , *PREECLAMPSIA , *STROKE - Abstract
We thank Dr. Messerli et al for their thought-provoking commentary, which asserts that long-acting calcium channel blockers are superior to beta blockers for the prevention of stroke in patients with preeclampsia. Long-standing hypertension and medical comorbidities may affect vascular response differently than acute preeclampsia, and preeclampsia itself is known to alter physiology.2 It cannot be assumed that findings in a nonpregnant population will be replicated in pregnant women. The relative safety and equivalence of these options is supported by a recent Cochrane review.5 Studies suggest that rapid treatment of severe hypertension with currently recommended medications does reduce morbidity.3,6 Ultimately, the most readily available, efficacious medication should be applied expeditiously to avoid known complications of severe hypertension, of which stroke is only one of several devastating outcomes.2,4. [Extracted from the article]
- Published
- 2019
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